prof. dr hab. Mariusz Ratajczak

prof. dr hab. Mariusz Ratajczak

EDUCATION 

1989/D.Sci./Habilitated Doctor in Internal Medicine Central Clinical Hospital WAM, Warsaw, Poland; based on published papers and prepared thesis:  „Changes in the biochemical parameters related to the bone marrow transplantation. Clinical and experimental studies.”

1986/Ph.D./Experimental Hematology, Polish Academy of Sciences, Warsaw, Poland; based on the dissertation: „Fetal liver as a source of hematopoietic stem cells for transplantations. Experimental and technical aspects.”

1981/M.D./Pomeranian School of Medicine, Szczecin, Poland; Diploma Magna cum  laude;  first in the class (among 280 students).

 

POSTGRADUATE TRAINING

1989-1992/Research Fellowship/University of Pennsylvania, Philadelphia, USA
1984-1986/Research Fellowship:/Polish Academy of Sciences, Warsaw, Poland
1984-1989/Residency:/CSK WAM, Warsaw
1986/Board Certification/Internal Medicine, Poland
1981-1984/Internship:/Pomeranian Medical School, Szczecin, Poland

 

ACADEMIC APPOINTMENTS

2007-/Director/Stem Cell Institute, James Graham Brown Cancer Center, University of Louisville, Louisville, USA
2007-/Visiting Professor/Kansai University, Osaka, Japan.
2008-/Visiting Professor/Fudan University, Shanghaj.
2006- /Professor/Department of Physiology, Pomeranian Medical University, Poland.
2002–/Professor/Department of Microbiology and Immunology, University of Louisville, KY, USA
2001 – 2007/Director/Stem Cell Biology Program, James Graham Brown Cancer Center, Louisville
2001– /Professor/Medicine, Department of Medicine, University of Louisville, Louisville
1999 – 2005/Professor/Head of Department of Transplantology at   Polish-American Children’s Hospital, CMUJ, Krakow, Poland
2000–2001/Research Associate Professor/Department of Pathology & Lab. Medicine, University of Pennsylvania School of Medicine, Philadelphia
1999–2000/Research AssociateProfessor/Medicine, Department of Medicine,University of Pennsylvania School of Medicine, Philadelphia
1998–1999/Research Assistant Professor/Medicine,  Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia
1996–1998/Research Assistant Professor/Department of Pathology and Laboratory Medicine, University of PennsylvaniaSchool of Medicine, Philadelphia
1992–1995/Senior Researcher Investigator/Department of Pathology, University of Pennsylvania School of Medicine, Philadelphia
1989–1994/Associate Professor/Internal Medicine, Center for Clinical and Experimental Medicine, Polish Academy of Sciences, Warsaw
1986–1989/Research Adjunct/Center for Clinical anExperimental Medicine, Polish Academy of Sciences, Warsaw
1981–1984/Research Assistant/Department of Clinical Gastroenterology, Pomeranian School of Medicine, Szczecin

 

AWARDS AND HONORS

2014 – Karl Landsteiner Life Achievement Award from the German Society of Transfusiology and Hematotherapy for discovery of VSELs and for identification of new mechanisms regulating stem cell mobilization.
2009-2015 – Visitng Professor, Kansai University, Osaka, Japan
2010 – Honorary Professorship, Ji Nan University, Guangzhou, China
2008 – Distinguished Faculty Award for Outstanding Scholarship and Research from the President of the University of Louisville.
2008 – Doctor honoris causa from the Medical University of Silesia.
2008 – Foreign Member of the Polish Academy of Art and Science
2007 – Mosaic Award from Jewish Family and Vocational Service.
2006 – The Annual Award in Medicine and Biology from The Foundation for Polish Science (The highest scientific award in Poland).
2006 – Hoening Endowed Chair in Cancer Biology at James Graham Brown Cancer Center, University of Louisville, Ky
2005 – Sniadecki Award from Polish Academy of Sciences
2004 – Individual Award from Polish Ministry of Health for Scientific Achievements
2002 – Chad Kopple Spirit Award from the Leukemia & Lymphoma Society
2001 – Honorary Member of Polish Society of Cytobiology and Histochemistry
1986 – Ph.D. thesis with Award
1981 – M.D. magna cum laude – first in class of 280 students
1980 – Nicolaus Copernicus Award from Polish Ministry of Health
1979 – Special Award for Young Student Scientists from Polish Academy of Sciences

 

MEDICAL & SCIENTIFIC SOCIETY MEMBERSHIPS

2008 – Foreign Member of the Polish Academy of Art and Science
2007 – Polish Academy of Sciences Committee for Pathophysiology
1999 – International Society of Experimental Hematology
1999 – American Society for Cancer Research
1997 – 2006 Polish Academy of Sciences, Committee for Tissue Culture & Molecular Pathology
1993 – American Society of Hematology
1986– 2005 Polish Academy of Sciences, Committee for Experimental Hematology,
1981– Polish Medical Society

 

EDITORIAL BOARDS & REVIEWING EXPERIENCE

Editorial Boards Present:

2012 – Journal of Stem Cell Rsearch and Therapy – Editor
2012 – Journal of Ovarian Research
2010 – Blood Cancer Journal
2009 – Stem Cell Reviews and Reports
2009 – Advances in Clinical and Experimental Medicine
2008 – The Journal of Clinical Investigation – Consulting Editor
2008 – Advances in Hematology
2008 – The Journal of Applied Genetics
2006 – The Journal of Cellular and Molecular Medicine
2006 – Central European Journal of Biology – Editor-in-Chief
2005 – Leukemia – Section Editor
1997 – Stem Cells

 

Ediorial Boards Past

2004 – 2008   Experimental Hematology
2009 – 2011   Experimental Hematology – Associate Editor
1998 – 2012   Folia Histochemica et Cytobiologica – Associate Editor

 

Reviewer for:  Science, Journal of Clinical Investigation, Blood, Proceedings of National Academy of Sciences USA, Journal of Cell Biology, Cancer Research, Molecular cancer Research, Experimental Cell Research, Experimental Hematology, Stem Cells, Leukemia, Nucleic Acids Research, Experimental Neurology

 

Grant Study Sections:

2008 – 2009   National Institute of Health – Hematopoiesis Study Section – standing member
2010 – 2012   National Institute of Health – Molecular and Cellular Hematology – standing member

Ad hoc:

2013- National Institute of Health, Tumor Microenvironment Study Scetion – ad hoc
2008- National Institute of Health, Intercellular Interactions Study Section – ad hoc
2007- National Heart, Lung and Blood Institute, Hematopoiesis Study Section – ad hoc
2006- National Heart, Lung and Blood Institute, Hematopoiesis Study Section – ad hoc
2006- National Institute of Helath, Hematopoiesis Special Panel – ad hoc
2005 – National Heart, Lung and Blood Institute, Hematopoiesis Study Section Special Panel
2005- National Heart, Lung and Blood Institute, Hemostasis/Thromb. – ad hoc
2005- National Heart, Lung and Blood Institute, Stem Cell Therapy Centers
2004 – National Cancer Institute Review Group, Clinical Studies

 

GRANT SUPPORT

5R01DK07420-07; (Ratajczak, MZ); 03/01/13-02/28/17;  1.80 calendar; NIH; $255,084; Novel hematopoietic effects of C3 cleavage fragments;The aim of this study is to investigate a role of complement in homing and mobilization of hematopoietic stem cells.

1R01HL112788-01A1; (Ratajczak, MZ); 06/01/13-03/31/17; 1.80 calendar; NIH; $263,776; Bioactive Lipids in Stem Cell Homing and Mobilization; We propose three interrelated aims to reappraise the role of SDF-1 in stem cell trafficking and address our central hypothesis that the bioactive lipids S1P and C1P play an important and presently unappreciated role in homing and mobilization of HSPCs.

2P0IHL078825-06; (Bolli R); 07/01/2011-05/31/2016;  0.24 calendar; NIH; $359,268; Protection of Ischemic Myocardium- CORE C

2P0IHL078825-06; (Bolli R); 07/01/2011-05/31/2016; 0.60 calendar; NIH; $203,364; Protection of Ischemic Myocardium- CORE D

1R43AI098325-01; (Rodgerson D);12/01/2011-02/28/2014; 1.20 calendar; NeoStem, Inc; $289,618; Development of Human, Autologous, Pluripotent Very Small Embryonic Like (VSELs) Stem Cells as a Countermeasure to Radiation Threat.;The aim of this study is testing the efficacy of murine and human VSELs to rescue the immune system of mice exposed to lethal irradiation.

 

INVITED LECTURES (selected)

  • September 23, 1992. „Antisense oligodeoxynucleotides as probes for studying human hematopoiesis”. Jahrestagung der Deutschen Gesellschaft fuer Haematologie und Onkologie, Berlin, Germany.
  • June 9, 1993.  „Antisense strategy. The perspectives of therapeutical use of antisense oligomers in the treatment of human leukemias.  Symposium in memory of Rudolf Virchow,  Szczecin, Poland.
  • June 14, 1993.     „The role of receptors with intrinsic tyrosine kinase activity in regulation of normal human haematopoiesis. V Annual Conference on Cell  Biology, Wroclaw, Poland.
  • June 22, 1994.     „Molecular mechanisms of the regulation of the human erythropoiesis.Clinical implications”. Conference of the Polish  Society of Haematology and Transfusiology,. Wroclaw.
  • June 26, 1994.      „Oligodeoxsynucleotide-based therapeutics of human leukemias.” 1st Berlin Symposium on the application of molecular biology to cancer patients.  Berlin, Germany.
  • October 22, 1994. „Isolation, storage and expansion of CD34+ bone marrow cells. Transplantological implications „. Conference on Bone Marrow Transplantation in Poland, Warsaw, Poland.
  • March 15, 1995. „Oligonucleotide therapeutics for human leukemias.” Antisense Therapy – International IBC. Conference. Charing Cross Medical School, London, UK.
  • April 12, 1995. „Oligonucleotide therapeutics for human leukemias.” The Treatment of Cancer: Beyond Chemotherapy. IBC International Conference, London, UK.
  • June 14, 1995. “Molecular mechanisms regulating the proliferation of the earliest human hematopoietic cells.” XVI Meeting of Polish Society of Haematology and Transfusiology. Warsaw, Poland.
  • November 14, 1995. „Contemporary methods of investigation of the molecular mechanisms regulating the proliferation and differentiation of human hemopoietic stem and progenitor cells”. 3rd Annual Meeting  of The Polish Section of the European Cell and Tissue Culture Society. Krakow, Poland.
  • June 22, 1996. “The biology of human hematopoietic stem cells. Transplantological implications”. Annual Meeting on Bone Marrow Transplantation, Poznan, Poland.
  • September, 24, 1996. “The role of receptors possessing intrinsic tyrosinekinase activity in regulating biology of the human earliest hematopoietic cells”. International Conference on Cellular Interactions, Poznan, Poland.
  • September, 24, 1996. ”The pathogenesis of the anemia of chronic disorders”. International Conference on Cellular Interactions, Poznan, Poland.
  • June 19, 1997. “The biology of human hematopoietic stem and progenitor cells”. 2nd Symposium of Tissue Cultures of Central European Countries, Krakow, Poland.
  • June 19, 1997.”The new trends for isolating and ex vivo expanding of  human early hematopoietic cells. Clinical implications.” 2nd Symposium of Tissue Cultures of Central European Countries,  Krakow, Poland.
  • September 17, 1997. “The application of FACS for studying expression of the intracellular proteins”. Annual Conference on Advances of  Cytometry in Clinical Medicine. Poznan, Poland.
  • September 17, 1997. “The application of FACS for isolating human earliest hematopoietic cells”. Annual Conference on Advances of  Cytometry in Clinical Medicine. Poznan, Poland.
  • September 24, 1997. “A new strategies for isolating and ex vivo expanding of human early hematopoietic cells. Clinical implications”.XVIIth Congress of the Polish Society of Hematology and       Transfusiology. Krakow, Poland.
  • May 13, 1998. “Isolation of human hematopoietic stem cells” Puget Sound Blood Center, Seattle, University of Washington.
  • August 13, 1998. “New strategies for isolating human earliest hematopoietic cells”. Center for Gene Therapy, Allegheny University, Philadelphia.
  • September 25, 1998. “The role of chemokines in HIV infection”. Annual Conference of the Polish Histochemical Society, Szczecin, Poland.
  • October 6, 1998.  “Hunting for the stem cells” University of Pennsylvania, Hematology/Oncology Research Conferences, Philadelphia.
  • May 11, 1999. “New strategies for isolation and ex vivo expansion of early human hematopoietic cells”. Coriell Institute, Camden.
  • June 24, 1999. “Influence of HIV infection on human hematopoiesis. Clinical implications”. XVIII Meeting of the Polish Society of Haematology. Lodz, Poland.
  • November 2, 1999. “Of CD34+ cells and HIV” University of Pennsylvania, Hematology/Oncology Research Conferences, Philadelphia.
  • September 11, 2000. “Of CD34+ cells and HIV”. University of Louisville, Louisville, KY.
  • September 17, 2000. “New strategies to ameliorate posttransplant related thrombocytopenia” – Plenary lecture – Annual Conference of Polish Society of Hematology, Warsaw, Poland.
  • March 4, 2002. “The role of CXCR4-SDF-1 axis in hematopoiesis”, Jewish Hospital, Louisville, Ky.
  • August 8, 2002. “CXCR4 – one receptor many functions”, Purdue University, West Lafayette, IN.
  • May 29, 2003. “The role of circulating stem cells in regeneration”, Plenary lecture – Annual Meeting of Polish Society of Hematology, Krakow, Poland.
  • June 18th, 2003. “Priming of SDF-1–CXCR4 axis: a new strategy to improve engraftment of hematopoietic stem cells.” American Red Cross Holland Laboratories, Rockville, MD.
  • October 23rd, 2003.  “The role of SDF-1-CXCR4 axis in circulation of tissue committed stem cells” Plenary lecture at 1st Annual Meeting of European Stem Cell Therapeutic Excellence Center, Cracow, Poland.
  • December 18th, 2003. “Tissue-committed early muscle, liver and neural cells reside in the bone marrow and can be isolated by chemotactic gradients to SDF-1, HGF/SF or LIF: A new perspective on plasticity of bone marrow-derived stem cells and aging.” Plenary lecture at 2nd International Meeting on Stem Cells, Beijing, China.
  • January 12th, 2004. “A new perspective on plasticity of bone marrow-derived stem cells and aging”. SCIRC Louisville, KY
  • May 16th, 2004. “Tissue committed stem cells reside in the bone marrow: novel insights into the “plasticity of adult stem cells” and the aging process. Plenary lecture at “From oocytes to stem cells. Progress in basics and applications”. Prague, Czech Republic.
  • May 18th, 2004. “Microparticles and their effects on stem cells.” Plenary lecture at 8th European Symposium on Platelet and Granulocyte Immunobiology, Rust, Burgenland, Austria.
  • June 7th, 2004. “Are stem cells plastic or heterogenous – that is the question.” – Plenary lecture at 2nd Annual Meeting of European Stem Cell Therapeutic Excellence Center, Cracow, Poland.
  • July 20th, 2004. “Tissue committed stem cells (TCSC) are deposited in the bone marrow early during ontogenesis as a mobile pool of stem cells for tissue/organ regeneration. A new insight into the phenomenon of stem cell plasticity and aging”. Presidential Symposium at 33rd Annual Meeting of the International Society of Experimental Hematology, New Orleans.
  • September 29th, 2004. “Are bone marrow stem cells plastic or heterogenous?” – Invited Speaker and Visiting Professor, Roger Williams Hospital and Cancer Center, Providence.
  • October 30th, 2004. “Bone marrow as a source of circulating CXCR4+ tissue committed stem cells for cardiac regeneration.” The 9th Myocardial Ischemia Symposium 2004.  Seoul, Korea.
  • December 17th, 2004. “Are bone marrow stem cells plastic or heterogenous – that is the question”. 3rd International Symposium on Hematopoietic Stem Cell Transplantation in Children. Poznan, Poland.
  • January 21st, 2005. “Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient.” 5th International Workshop on Non-meyloablative Stem Cell Transplantation. Cancun, Mexico.
  • February 15th, 2005. “A novel insight into cancer metastasis” University of Alberta, Cross Cancer Institute, Edmonton, Canada.
  • March 3rd, 2005. “Are Bone Marrow Stem Cells Plastic or Heterogenous – That is the Question”. Cancer Center at University of Indiana, Indianapolis, USA.
  • April 6th, 2005. “Bone Marrow as a Home of Heterogenous Populations of Nonhematopoietic Stem Cells”. Harvard Medical School Boston, USA.
  • April 15th, 2005. “Are Bone Marrow Stem Cells Plastic or Heterogenous – That is the Question”. European School of Hematology, Cascais, Portugal.
  • May 19th, 2005. “Stem cells our key to longevity” – Opening lecture – XII Meeting of the Polish Society of Experimental and Clinical Immunology, Lublin, Poland.
  • June 27th, 2005. “Isolation of cardiac progenitors from bone marrow and mobilized peripheral blood using flow sorting capabilities” – Plenary lecture at International Meeting “New Frontiers in Cytometry”, Moscow, Russia.
  • September 11th, 2005. “Bone marrow as a source of non-hematopoietic stem cells”. Meeting of the Polish Society of Hematology and Transfusiology. Wisla, Poland.
  • September 18th, 2005. “Nonhematopoietic bone marrow-derived stem cells” – Invited Lecture 67th Annual Meeting of the Japanese Society of Hematology (JSH) and the 47th Annual Meeting of the Japanese Society of Clinical Hematology (JSCH) in Yokohama, Japan.
  • September 21st, 2005. “A population of embryonic-like stem cells identified in human bone marrow” Kansai University, Osaka, Japan.
  • October 7th, 2005. “Normal Stem Cells “Jedi” that went over to the “dark side”. Plenary lecture at 3rd Annual Meeting of European Stem Cell Therapeutic Excellence Center, Cracow, Poland.
  • November 4th, 2005. “UCB Hematopoietic Stem Cell Homing: Implications for Engraftment”. Case    Western Reserve University. Cleveland, USA.
  • March 2nd, 2006. “VSEL – very small embryonic like stem cells”. Southern Society for Clinical Investigation, Atlanta, USA.
  • March 23rd, 2005. “Stem cells our key to longevity”. Polish Academy of Sciences, Warsaw, Poland.
  • April 24th, 2006. “Adult bone marrow derived very small embryonic like (VSEL) stem cells”. Annual Canadian Blood and Marrow Transplant Group Meeting, Edmonton, Canada.
  • May 24th, 2006. – “Novel biological aspects of bone marrow stem cells”. The 10th ESH-EBMT Training Course on Blood and Marrow Transplantation, Warsaw, Poland.
  • June 5th, 2006. – “In vivo and in vitro evidence that the third complement component (C3) cleavage fragments enhance platelet production during reactive thrombocytosis”. 3rd Annual Innate Immunity Meeting, Corfu, Greece.
  • June 10th, 2006. – “Stem cell therapies a key to longevity” XXII Annual Congress “Fetus as a patient”. Poznan, Poland
  • June 15th, 2006. – “Very small embryonic like stem cells” – University of Illinois. Chicago, USA.
  • June 24th, 2006. – “Stem cell plasticity – new paradigms” – Medical College of Georgia, Augusta, USA.
  • August 1st, 2006. – “Very small embryonic like (VSEL) stem cells – our key to longevity. Blood Center Milawukee, USA.
  • September 15th, 2006. “Physiological and patho-physiological consequences of circulation of very small embryonic like (VSEL) stem cells”. XXIII Annual Meeting of Polish Physiological Society. Inauguration lecture, Warsaw, Poland.
  • September 19th, 2006 – “Very small embryonic like (VSEL) stem cells – our key to longevity and passkey to cancerogenesis”. Alfried Krupp Tumorbiology Conference, University of Greifswald, Greifswald, Germany.
  • October 6, 2006. –“VSEL our key to longevity”, Biology and Clinical Applications of Mesenchymal Stem Cells. Mandelieu La Napoule, France.
  • October 10, 2006. – “Non-hematopoietic bone marrow-derived stem cells”. 21 Annual Clinical Cytometry Society Meeting, Long Beach, CA, USA.
  • October 23, 2006 – “A role of SDF-1-CXCR4 axis in stem cell mobilization, trafficking and homing”. Fudan University, Shanghai, China.
  • October 24, 2006 – “A role of bone marrow in organ/tissue regeneration”.   Fudan University, Shanghai, China.
  • October 26, 2006 – “The role of SDF-1-CXCR4 axis in developmental migration of normal stem cells and metastasis of cancer stem cells”. Fudan University, Shanghai, China.
  • November 1, 2006 – “Physiological and Pathological Consequences of Very Small Embryonic Like (VSEL) Stem Cells in Adult Bone Marrow”.  Lerner Research Institute, Cleveland, OH.
  • November 8th, 2006 – “Physiological and Pathological Consequences of Very Small Embryonic Like (VSEL) Stem Cells in Adult Bone Marrow”. Medical College of Georgia, Augusta, GA.
  • November 20st, 2006. – “Very small embryonic like (VSEL) stem cells – our key to longevity. University of Pennsylvania, Philadelphia, PA.
  • January 9th, 2007 – “Embryonic like stem cells in adult tissues”. Case Western Univ., Cleveland, OH
  • January 18th, 2007 – “The role of complement in homing and mobilization of stem cells” – Univ. of Greifswald, Greifswald, Germany.
  • January 26th, 2007 – “Physiological and pathological consequences of a presence of circulating very small embryonic-like stem cells”. University of Dresden, Dresden, Germany.
  • January 31st, 2007 – “SDF-1-CXCR4 axis as regulator of stem cell trafficking”. Med. Coll. Wisconsin, Milwaukee, WN.
  • February 13th, 2007 – “Hetreogenous populations of stem cells reside in the bone marrow: which therapeutic implications?” “Normal and malignant stem cells 2007”, Collegio Ghislieri, Pavia, Italy.
  • February 22nd, 2007 – “A hypothesis for an embryonic origin of pluripotent Oct-4+ stem cells in adult bone marrow and other tissues”. University of Florida, Gainesville, FL.
  • March 15th, 2007 – “A hypothesis for an embryonic origin of pluripotent Oct-4+ stem cells in adult bone marrow and other tissues”. Univ. of Michigan, Ann Arbor, MI
  • April 28th, 2007 – “Stem cells and stem cell plasticity – fact or artifact?” – University of Southern Indiana, Evansville, IN.
  • May 23rd, 2007 – “VSEL and heart regeneration” – 5th EuroPCR Meeting, Barcelona, Spain.
  • June 14th, 2007 – “The role of complement in stem cell trafficking”. IV Innate Immunity Meeting, Porto Heli, Greece.
  • June 26th, 2007 – “The identification of embryonic like SSEA+ OCT-4+ CXCR4+ stem cells in adult bone marrow and cord blood”. Plenary lecture at 13th Annual Meeting of the International Society for Cellular Therapy”.
  • July 25th, 2007 – “The role of complement system in trafficking of stem cells”. International stem cell meeting. Foz do Iguassu, Brazil.
  • September 6th, 2007 – “Stem cells key to longevity” – Plenary lecture at Annual Meeting of Polish Society of Pediatric Endocrinology, Cracow, Poland.
  • September 7th, 2007 – “Stem cells in regenerative medicine” – Plenary lecture at Pomeranian Alergology Symposium, Szczecin, Poland.
  • September 19th, 2007 – “The role of bone marrow-derived stem cells in regenerative medicine – new paradigms and future directions” – Plenary lecture at 2nd Annual Congress of Genetic, Warsaw, Poland.
  • September 24th, 2007 – “Adult bone marrow – and cord blood-derived very small embryonic like stem cells” – Plenary lecture at International Meeting on Regeneration, Mulhouse, France.
  • October 6th, 2007 – “Very small embryonic-like (VSEL) stem cells – implications for aging”. Plenary lecture at European Conference on Cancer and Aging “Seneca 2007”, Warsaw, Poland.
  • October 8th, 2007 – “Stem cells our key to longevity”. Opening Lecture at the Central Inauguration of Academic Year of the Medical Schools in Poland. Katowice, Poland.
  • October 13th, 2007 – “Stem cells in regenerative medicine” – Plenary lecture at Annual Meeting of the Polish Gynecological Society. Lublin, Poland.
  • October 19th, 2007 – “Identification of very small embryonic like (VSEL) stem cells in cord blood”. Invited talk at Annual European Cord Blood Meeting, Paris, France.
  • October 27th, 2007 – “A hypothesis for an embryonic origin of pluripotent Oct-4+ stem cells in adult bone marrow and other tissues”. Plenary lecture at the 21st Century Center of Excellence Meeting, Osaka, Japan.
  • November 26th, 2007 – “Stem cell plasticity – revised”. Jewish Hospital Louisville, KY
  • December 5th, 2007 – “Bone marrow-derived stem cells”. Kentucky Lion Eye Clinic Louisville, Ky.
  • January 26th, – “Small cells in bone marrow”. Graft versus Host – Graft versus Leukemia symposium, Bad Aibling, Germany.
  • February 17th, 2008 – “Identification of VSEL stem cells in adult tissues”. Plenary leture at ABBMT Tandem Meeting. San Diego, CA
  • February 23rd, 2008 – “Hypothesis for embryonic deposition of VSEL in adult tissues”. Plenary lecture at the symposium “Stem Cells: from Bench to Bedside”- organized by Swiss Institute for Stem Cell Biology. Zurich, Switzerland.
  • April 18th, 2008 – “A role of complement in homing and mobilization of stem cells”. Plenary lecture at Polish School of Hematology, Cracow, Poland.
  • May 1st, 2008. – “Small cells with great potential”. Derby Lecture at the University of Louisville, Louisville, Ky.
  • June 4th, 2008 – “Very small embryonic like stem cells in adult tissues” – 2nd Annual ESTOOL Meeting, Budapest, Hungary.
  • June 19th, 2008 – “Identification of pluripotent stem cells in adult tissues”. XVII Stem Cell Meeting, Wilsede, Germany.
  • June 24th, 2008 – “The studies in various murine strains with defects in activation of complement cascade (CC) reveal both pivotal and peliotropic role of CC in mobilization of hematopoietic/stem progenitor cells. 5th International Conference on Innate Immunity. Chania, Greece.
  • August 23rd, 2008 – “Identification of very small embryonic like stem cells in adult tissues”. XIII International Congress of Histochemistry and Cytochemistry, Gdansk, Poland.
  • September 1st, 2008 – “VSEL – physiological and pathological consequences”. Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria.
  • September 5th, 2008 – “The role of stem cells in aging”. Annual Meeting of the Anti-Aging Society. Warsaw, Poland
  • September 8th, 2008 – “The identification of VSEL stem cells in adult organs”. Opening lecture at the Annual Meeting of the Polish Society of Cell Biology and Biochemistry, Olsztyn, Poland.
  • September 15th, 2008 – “Stem cell therapeutics – hope and reality”. EVG Meeting, Cracow, Poland.
  • September 18th, 2008 – “VSEL – newly discovered population of stem cells”. 7th Stem Cell Meeting, Meersburg, Germany.
  • October 13th, 2008 – “Very small embryonic like stem cells (VSELs) identified in adult tissues”. Thomas Jefferson University, Philadelphia, PA.
  • October 17th, 2008 – “Cord blood-derived VSELs” – 20th Anniversary Cord Blood Symposium, Mandelieu, France.
  • November 8th, 2008 – “Identification of very small embryonic like (VSEL) stem cells in adult  tissues – physiological and pathological consequences” – 2008 Taiwan International Somatic Stem Cell Symposium, Taipei, Taiwan.
  • November 13th, 2008 – “Stem cells and regenerative medicine”. Soochow University, Souzhou, China.
  • November 22nd, 2008 – “Future of stem cell therapies”. Jagiellonian University, Cracow, Poland.
  • December 4th, 2008 – “The novel role of complement in stem cell trafficking”. Thomas Jefferson University, Philadelphia, PA.
  • February 26th, 2009 – “The novel role of complement in stem cell homing and mobilization”. University of Texas, Houston, TX.
  • April 13th, 2009 – “Stem cells our key to longevity” – New York Blood Center, NY.
  • April 21st, 2009 – “Very small embryonic like stem cells, characterization and biological relevance” Annual Experimental Biology Meeting, New Orleans, LA.
  • April 30th, 2009 – “Stem cells in regenerative medicine”. Louisiana State University at Paddington, Baton Rouge, LA
  • June 6th, 2009 – “Optimization of Isolation and Further Molecular and Functional Characterization of SSEA-4+/Oct-4+/CD133+/CXCR4+/LIN/CD45 Very Small Embryonic-Like Stem Cells (VSELs) Isolated from Umbilical Cord Blood.” 7th Annual International Cord Blood Transplantation Symposium, Los Angeles, CA.
  • June 14th, 2009 – “Multilineage differentiation of small Oct-4+ cells isolated from adult tissues”. Weizmann Institute, Rehovot, Israel.
  • June 15th, 2009 – “Adult Tissues-derived Very Small Embryonic Like (VSEL) Stem Cells – Characterization, Developmental Origin and Biological Significance”, 3rg Israeli Stem Cell Meeting, Tel Aviv, Israel.
  • June 19th, 2009 – “Stem Cell therapeutics – hope and dangers”. XVIII Congress of Polish Society of Hematology and Transfusiology, Wroclaw, Poland.
  • June 23rd, 2009 – “The role of C5 complement component in stem cell mobilization”. 6th Congress on Innate Immunity, Heraklion, Greece.
  • September 12th, 2009 – “Very Small Embryonic Stem Cells – further characterization”. 3rd Meeting of European Vascular Biology Organization, Marseille, France.
  • September 17th, 2009 – “Stem cells and regenerative medicine” – 50th Congress of Polish Society of Gynecology, Lublin, Poland.
  • September 27th, 2009 – “Very Small Embryonic Like (VSEL) Stem Cells – Characterization, Developmental Origin and Biological Significance”. Medical University of South Carolina, Charleston, SC.
  • October 23rd, 2009 – “VSELs and potential clinical applications”. Nebraska University Medical College, Omaha, NE.
  • November 19th, 2009 – “VSELs – identification and biological role”. 3rd International Meeting on Non-Hematopoietic Stem Cells. Tubingen, Germany
  • November 22nd, 2009 – Very Small Embryonic Like (VSEL) Stem Cells – Characterization, Developmental Origin and Biological Significance “. University of Ulm, Germany.
  • November 27th, 2009 – “Non-hematopoietic Stem Cells in BM” – International Bone Marrow Transplantation Conference. Warsaw, Poland.
  • January 22nd, 2010 – „Innate Immunity – an underappreciated conductor of stem cell trafficking” – Kentucky Lion Eye Clinic Louisville, Ky.
  • January 27th, 2010 – “Developmental Origin and Biological Significance of Oct-4+ Very Small Embryonic Like Stem Cells (VSELs) Isolated From Adult Tissues” – Yale University, New Haven CT.
  • February 18th, 2010 – “Very small embryonic like stem cells (VSELs) and regenerative medicine”. University of WV, Morgantown, WV.
  • March 9th, 2010 – The role of complement cascade in stem cell trafficking. ISCT Univ. of Louisville, Louisville, Ky.
  • April 26th, 2010 – Novel View on Stem Cell Homing/Engraftment and Mobilization – Involvement of Complement Cascade – Translational Implications. University of West Virginia, Morgantown, WV.
  • May 14th, 2010 – VSELs and their potential clinical applications. 1st International Conference of Frontiers of Regenerative Medicine and Biomedical Science. Guangzhou, China.
  • May 26th, 2010 – Umbilical cord blood (UCB)-derived CD45/SSEA-4+/OCT-4+/CD133+/CXCR4+/Linvery small embryonic/epiblast like stem cells (VSELs) – Potential Clinical Applications. 16th Presidential Symposium – Annual Meeting of International Society for Cellular Therapy. Philadelphia, PA.
  • June 3rd, 2010 – Umbilical cord blood-derived VSELs – an update. International Umbilical Cord Blood Transplantation Symposium. San Francisco, CA.
  • June 4th, 2010 – New strategies to accelerate engraftment/homing of UCB HSPCs. International Umbilical Cord Blood Transplantation Symposium. San Francisco, CA.
  • June 12th, 2010 – Future of Stem Cell Therapies. Opening Lecture – XIV Congress of Polish Society of Gastroenterology. Szczecin, Poland.
  • July 5th, 2010 – The role of complement system in stem cell mobilization. VII International Meeting on Innate Immunity. Rhodes, Greece.
  • July 14th, 2010 – VSELs – potential application in regenerative medicine. 3rd International Congress on Stem Cells and Tissue Formation. Dresden, Germany.
  • August 14th, 2010 – Potential application of VSELs in regenerative medicine. Burnham Institute, La Jolla, CA.
  • September 7th, 2010 – Very small embryonic like stem cells – a key for longevity and passkey for tumorigenesis. Feinstein Medical Institute, Manhasset, NY.
  • September 9th, 2010 – Umbilical Cord Blood derived VSELs- an update. 2nd International Symposium Stem Cells: from bench to bedside. Gmunden, Austria.
  • September 21st, 2010 – VSELs – origin, biology and clinical implications. 1st International Stem Cell Meeting on Neurogenesis. Sao Paulo, Brazil.
  • October 6th, 2010 – Future of Stem Cell Therapies. National Korean University, Seoul, Korea.
  • October 8th 2010 – Very small embryonic like stem cells isolated from adult tissues – origin, biological significance and potential applications. 22nd Annual Meeting of the Korean Society for Molecular and Cellular Biology, Seoul, Korea.
  • October 22nd, 2010 – VSELs – developmental origin and potential clinical applications. Keynote speaker at 18th Annual Research Celebration, Rhode Island Hospital, Providence, RI.
  • December 18th, 2010 – VSELs research – update and future directions. 3rd POIG Meeting, Warsaw, Poland.
  • December 27th, 2010 – Molecular signature and epigenetic mechanisms that regulate VSELs proliferation. Invited lecture at Fudan University, Shanghai, China.
  • December 28th, 2010 – The novel role of complement system and bioactive lipids in stem cell homing and mobilization. Invited lecture at Fudan University, Shanghai, China.
  • January 11th, 2011 – VSELs – an update. Neostem SAB, Boston, MA, USA..
  • February 18th 2011 – Pluripotent stem cells isolated from adult tissues. NYMC, Valhalla, NY, USA.
  • March 17th, 2011 – The role of complement and bioactive lipids in stem cell trafficking. Lion Eye Clinic, UofL, Louisville, KY, USA.
  • April 15th, 2011 – Pluripotent stem cells: iPS and VSELs Technology in Hematopoietic Regenerative Medicine. 2011 ASPHO Meeting, Baltimore, MD, USA.
  • April 22nd, 2011 – Pleiotropic effects of microvesicles. 1st International Symposium on exosomes. Providence, RI, USA.
  • May 26th, 2011 – Stem Cells in tissue organ regeneration. Opening lecture, Annual Meeting of Polish Society of Psychiatry. Miedzyzdroje, Poland.
  • May   27th, 2011 – VSELs an update. 1st Baltic Stem Cell Meeting, Opening lecture. Szczecin, Poland.
  • June 8th, 2011 – Stem Cell Therapies, 75th Annual meeting of Polish-American Institute of Science. Washington DC, USA
  • June 27th, 2011 – The role of sphingolipids in stem cell trafficking. 6th Aegean Innate Immunity Meeting, Rhodes, Greece.
  • August 31st, 2011 – Very small embryonic like stem cells – our key to longevity and passkey to tumorigenesis. 5th SENS Aging Foundation Meeting, Cambridge, UK.
  • September 17th, 2011 – Stem cells and aging.  XXV Meeting of Polish Society of Physiology, Olsztyn, Poland.
  • October 17th, 2011 – VSELs an update. Stem Cell Symposium. University of Lund, Lund, Sweden.
  • October 26th, 2011 – Stem cells in regeneration. XII Annual Meeting of German Blood Banks, Dresden, Germany.
  • November 12th, 2011 – VSELs non-controversial PSCs. 1st Vatican conference on Adult Stem Cells. Vatican City, Rome, Italy.
  • November 17th, 2011. Stem cells and regenerative medicine. University of Kentucky, Lexington, USA.
  • November 29th, 2011 – Stem cells and regenerative medicine. Medical University of Bialystok, Bialystok, Poland.
  • December 1st, 2011 – Mechanisms regulating trafficking of stem cells. Medical University of Bialystok, Bialystok, Poland.
  • December 19th, 2011 – Adult stem cell therapies – time for VSELs. Soochow University, Suzhou, China.
  • January 19th, 2012 – VSELs our key to longevity. Tulane University, New Orleans, Louisiana, USA.
  • February 24th, 2012 – VSELs are key to longevity. 34th Annual Meeting of Japanese Society for Stem Cell Therapies. Osaka, Japan.
  • February 27th, 2012 –  VSELs an update. Special Forum on Stem Cell Therapies. Osaka, Japan.
  • March 8th, 2012 – Controversies in stem cell therapy. Conference on Ethics in Science Bialystok, Poland.
  • March 17th, 2012 – Potential role of VSELs in regenerative medicine. Perspectives in Cell- and Gene-Based Medicines. Frankfurt, Germany.
  • March 19th, 2012 – Very Small Embryonic Like Stem Cells (VSELs) – our key to regeneration, longevity and passkey to cancer. Disputationes 2012, Florence, Italy.
  • April 8th, 2012 – VSELs a rosetts stone to understand aging and cnacer. JGB Cancer Center, Louisville, USA
  • April 25th, 2012 – Vest small embryonic likes stem cells as a rosetta stone to undesratnd aging and cancer. Stony Brook, USA.
  • May 10th, 2012 – The role of complement and bioactive lipids in stem cell trafficking. X!! European Symposium on Granulocytes and Platelets. Openning Lecture, Warsaw, Poland.
  • May 15th, 2012 – Mechanisms of mobilization and homing of hematopoietic stem cells revisited. – Inst. Cell. Therap., Louisville, USA.
  • May 18th, 2012 – Basic biology of paracrine factors and stem cells. American Association of Aging, Orlando, Florida.
  • May 18th, 2012 – Clinical effects of stem cell/paracrine interactions. American Association of Aging, Orlando, Florida.
  • May 18th, 2012 – Current research on the effects of stem cell paracrine factors e.g., exosomes. American Association of Aging, Orlando, Florida.
  • June 7th, 2012 – Very small embryonic like stem cells (VSELs) as Rosetta stone to understand aging and cancer. Fudan University, Shanghai, China.
  • June 8th, 2012 – The role of complement in mobilization, homing and engraftment of hematopoietic setm/progenitor cells – a novel link between innate immunity and hematopoiesis. Fudan University, Shanghai, China.
  • June 11th, 2012 – Clinical effects of stem cell-derived paracrine soluble factors and microvesciels. Fudan University, Shanghai, China.
  • June 15th, 2012 – VSELs a Rosetta stone to understand cancer and aging. Hematology conference. UofL, Louisville, Ky
  • June 20th, 2012 – VSELs a new players. Digestive Disorder Federeation Meeting, Liverpool, UK.
  • July 11th, 2012 – VSELs – as Rosetta stone to understanding tissue rejuvenation, aging and cancer, Center of Biomedical Research Excellence (COBRE), Roger Williams Medical Center, Providence, Rhode Island.
  • August 21st, 2012 – VSELs and their potential clinical applications. FECTs Meeting, Katowice, Poland.
  • September 12th, 2012 – VSELs and update – UofL Dept. of Cardiology Ground Rounds, Louisville, Poland.
  • September 21st, 2012 – Mechanisms that orchestrate stem cell mobilization. Hematologica Conference. Sopot, Poland.
  • October 5th, 2012 – Stem cells current status of research, ethics and future. Innaugurational lecture for new academic year.  Medical University, Bialystok, Poland.
  • October 6th, 2012 – Stem cells current status of research, ethics and future. Innaugurational lecture for new academic year. Pomeranian Medical University, Szczecin, Poland.
  • October 12th, 2012 – VSEL – our key to longevity and passkey to cancerogenesis. XVII World Cancer Congress. Hersonissos, Greece.
  • November 29th, 2012 – VSEL a Rosetta Stone to understand aging and cancer. Boston CHOP, Harvard University, Boston, MA.
  • December 3rd, 2012 – Stem cells and regenerative medicine. Warsaw Medical University, Warsaw, Poland.
  • March 19th, 2013 – Quo Vadis Regenrative Medicine? EU Parliament, Brussels, Belgium.
  • April 13th, 2013 – VSELs and aging. 2nd International Conference on Regenerative Medcicne, Vatican, Rome, Italy.
  • May 3rd, 2013 – The presence of very small embryonic like stem cells (VSELs) in adult tissues  and an emerging role of microvesicles, exosomes and paracrine signals in regenerative medicine – towards development of novel therapeutic approaches. Univ of Dresden, Dresden, Germany.
  • May 6th, 2013 – New strategies in regenerative medcine. Fudan Univ. Shanghai, China.
  • May 7th, 2013 – VSELs and update. Fudan. Univ, China.
  • May 13th, 2013The role of bioactive lipids in stem cell trafficking. Fudan Univ. Shangai, China.
  • May 14th, 2013 – The role of complement in stem cell homing an dmobilization. Fudan Univ. Shanghai, China.
  • May 30th, 2013 – Quo vadis regenerative medicine? Opening lecture. 2nd Baltic Stem Cell Meeting, Szcecin, Poland.
  • June 13th, 2013 – HIV unwanted guest in bone marrow. Opening lecture, AIDS Symposium, Cracow, Poland.
  • June 22nd, 2013 – A novel view on involvement of complement cascade (CC) and sphingosine-1 phosphate (S1P) in pathogenesis of Paroxysmal Nocturnal Hemoglobinuria (PNH). Complement Theraputic Conference, Kos, Greece.
  • July 2nd, 2013 – The presence of very small embryonic like stem cells (VSELs) in adult tissues  and an emerging role of microvesicles, exosomes and paracrine signals in regenerative medicine – towards development of novel therapeutic approaches. XIII World Congress on Toxicology, Seoul, Korea.
  • July 2nd, 2013 – Novek strategies in regenerative medicine. Catholic University, Seoul, Korea.
  • July 3rd, 2013 – The presence of very small embryonic like stem cells (VSELs) in adult tissues  and an emerging role of microvesicles, exosomes and paracrine signals in regenerative medicine. Seoul National University, Seoul, Korea.
  • July 3rd, 2013 – Very Small Embryonic Like Stem Cells – practical applications. Ulsan University, Seoul, Korea.
  • August 22nd, 2013 – Effect of insulin growth factors and somatotrophic signaling on stem cells, tissue organ regeneration, aging and tumor development. 20th Meeting of Brasilian Society of Biology, Caxambou, Brasil.
  • August 27th, 2013 – VSELs and insulin like growth factors signaling. Sao Paulo University, Sao Paulo, Brasil.
  • September 18th, 2013 – Stem cells and regenerative medicine. 66th Congress of Polish Surgeons, Warsaw, Poland.
  • September 26th, 2013 – Quo vadis regenerative medicine? Openning Lecture at 25th Congress of Polish Society of Hematology and Transfusiology. Poznan, Poland.
  • October 11th, 2013 – The role of bioactive sphigolipids in metastasis of rhabdomyosarcoma cells. XVIII World Congress Advances in Oncology. Hersonissos, Greece.
  • October 16th, 2013 – Regenerative medicine in cardiovascular diseases – cell therapies and paracrine effects. Innovative Technologies in Biomedicine. Cracow, Poland.
  • Ocober 22nd, 2013 – VSELs as a key to understand regeneration and aging. Univ. of Califronia Davis, Los Angeles, CA.
  • November 24th, 2013. Umbilical Cord Blood Stem Cells. Annual Meeting of Obstetricians. Cracow, Poland.
  • December 13th, 2013. Stem cells in lung regeneration. Annual Meeting of pulmonary surgeons. Sczecin, Poland.
  • December 16th, 2013. Very small embryonic-like stem cells and update. Annual Meeting on Stem Cells. Wroclaw, Poalnd.
  • December 19th, 2013. Regenerative Medicine today and tomorrow. Medical University of Bialystok, Bialystok, Poland.
  • January 24th, 2014. Quo Vadis Regenerative Medicine? –  of stem cells, regeneration, aging and cancer. European Conference of Oncology Pharmacy. Hamburg, Germany.
  • February 20th, 2014. Stem cells and regenrative medicine. Meharry Medical College, Nasvville, TN, USA.
  • March 11th, 2014. Novel view on stem cell homing and mobilization. Stem Cell Meeting. Providence, Rhode Island, USA.
  • May13th, 2014. Current ststus and future of regenerative medcine. Biotechnology 2014 Meeting. Jagiellonian University, Cracow, Poland.
  • May 18th, 2014. Stem cells in aging and regenration. 43rd Annual Meeting of Brazilian Society of Biochemistry. Foz Do Igazu, Brazil.
  • June 5th, 2014. Quo Vadis Regenerative Medicine? International Meeting on Advances in Psychiatry. Warsaw, Poland.
  • June 13th, 2014. Pivotal Role of Paracrine Effects in Stem Cell Therapies in Regenerative Medicine – Can we Translate Stem Cell-Secreted Paracrine Factors and Extracellular Microvesicles into Better Therapeutic Strategies? International Extracellular Vesciles Symposium. Providence, Rhode Island, USA.
  • June 18th, 2014. Quo vadis regenerative medicine – stem cells in regeneration, aging and cancerogenesis. Openning lecture at the Annul;a Meeting of the European Society of Oncological Therapy. Cracow, Poland.
  • June 19th, 2014. Today and future of regenerative medicine. XV Meeting of the Polish Society of Experimental and Clinical Immunology. Wroclaw, Poland.
  • September 1st, 2014. Quo Vadis Regenerative Medicine – of stem cells aging and cancerogensis. Univ of Bern, Switzerland.

 

Ph.D. THESES SUPERVISION (MENTHOR)

1995 – Kuczyński, Wojtek MD, PhD – summa cum laude
1996 – Nieborowska, Skorska Margaret MD, PhD  – summa cum laude
1997 – Hałasa, Maciek  MD, PhD – summa cum laude
1997 – Marlicz, Wojtek MD, PhD –  summa cum laude
1997 – Honczarenko, Marek MD, PhD –  summa cum laude
2000 – Majka, Marcin PhD – cum laude
2000 – Paczkowska, Edyta MD, PhD
2002 –  Baj-Krzyworzeka, Monika PhD –  summa cum laude
2003  – Kijowski, Jacek MD, PhD – summa cum laude
2004  – Kucia, Magda PhD – summa cum laude
2004  – Jankowski, Kacper PhD – summa cum laude
2004  – Reca, Ryan PhD – Dean’s Citation
2005  – Trzyna, Ela PhD
2007  – Danuta Jarocha PhD
2007  – Marcinowska, Agnieszka – MD, PhD
2007  – Michalowska, Anna – MD, PhD
2009  – Wysoczynski, Marcin – PhD – summa cum laude
2011 –  Wan Wu MD, PhD
2013 – Katarzyna Mierzejewska – PhD – summa cum laude
2013 – Ewa Bryndza – PhD
2013 – Joanna Tarnowska – MD, PhD

 

PUBLICATIONS

BOOK

1. Ratajczak M.Z.  Changes in the biochemical parameters of the patients after bone marrow transplantation. Clinical and experimental studies. Medical Center of Postgraduate Education WAM, Lodz 1989.

BOOK CHAPTERS

1.  Ratajczak M.Z., Gewirtz A.M.: Role of the c-kit protooncogene in normal and malignant human hematopoiesis. In: Molecular Biology of Haematopoiesis, vol. II (red. Abraham N., Konwalinka G., Marks P., Sachs L., Tavassoli M.) , Intercept Ltd, 1992 (449-456).
2.     Ratajczak M.Z., Gewirtz A.M.: Oligonucleotide based therapeutics of human malignancies. In: Nucleic Acids & Molecular Biology, vol. VIII, (red. F. Eckstein), Springer Verlag, Berlin – Heidelberg 1994, 298 – 326.
3.     Kregenow D., Ratajczak M.Z., Gewirtz A.M.: Disrupting the flow of genetic information with antisense oligodeoxynucleotides: research and therapeutic applications. In: Delivery strategies for antisense oligonucleotide therapeutics. S. Akhtar (ed.), CRC, New York, 1994, pp. 1-15.
4.     Gewirtz A.M., Ratajczak M.Z.: Perturbing hematopoietic cell gene expression with oligodeoxynucleotides. Research and clinical applications. In: Applied Antisense Oligonucleotide Technology, (CA. Stein, AM. Krieg, eds.) Wiley-Liss 1998, New York, Singapore, Toronto, pp. 299-315.
5.     Ptasznik A., Ratajczak M.Z.: Hematology of mononuclear phagocytes. In:  Ultrastructure and cell function. Vol 4 (J. Kawiak and E. Osuchowska eds.), PWN, Warsaw, 1989.
6.     Jedrzejczak W.W.,  Szczylik C.,  Ratajczak M.Z.,  Pojda Z.,: Bone marrow transplantation. In: Ultrastructure and cell function. Vol 5. (J. Kawiak and E. Osuchowska, eds.), PWN, Warsaw, 1991.
7.     Ratajczak M.Z, Szwech P.: Hybrid hematopoietins. In: Cytokines. Clinical applications. (W.W. Jedrzejczak, M. Podolak-Dawidziak, eds.), Volume, Warsaw. 1997.
8.     Ratajczak M.Z.: The role of the growth factors acting through the receptors with intrinsic tyrosine kinase activity in the regulation of the proliferation of the early human haematopoietic cells. In: Fizjologia krwiotworzenia wraz z metodyka badawacza. (Dabrowski Z. ed.), PWN, Krakow, 1998.
9.   Ratajczak M.Z., Gewirtz A.M.:  Oligodeoxynucleotide based therapeutics for human leukemias. In: Molecular aspects of cancer and its therapy. (A. Mackiewicz, P.B. Sehgal, eds.), Birkhauser Verlag, Basel, 1998, pp. 163-177.
10. Calabretta B., Skorski T., Zon G., Ratajczak M.Z., Gewirtz A.M.: Antisense strategies in the treatment of leukemias. In: Gene therapy of cancer. (E.C. Lattime, S.L. Gerson, eds.), Academic Press, San Diego, London, Boston 1998, pp. 223-232.
11. Allendorf, D. J., G. R. Ostroff, J. T. Baran, C. W. Dyke, M. Z. Ratajczak, G. D. Ross. 2003. Oral WGP beta glucan treatment accelerates myeloid recovery and survival after radiation exposure. In:  BTR 2003: Unified Science & Technology for Reducing Biological Threats & Countering Terrorism. Univ. New Mexico, Albuquerque. pp. 104-113.
12. Majka M, Ratajczak M.Z. 2006. Biological role of the CXCR4-SDF-1 axis in normal human hematopoietic cells. In: Transmembrane signaling protocols (Ydar A, Bodduluri H, eds.), Humana Press, Totowa, New Jersey. pp. 103-114.
13. Ratajczak M.Z. 2007. Hetreogenous populations of stem cells reside in the bone marrow: which therapeutic implications? In: Progressi in Biologia e Medicina, Bernasconi C (ed), Collegio Ghislieri, Pavia, Italy. pp.72-81.
14. Ratajczak MZ, Reca R, Wysoczynski M, Kucia M, Ratajczak J. A role of complement system in mobilization and homing of hematopoietic stem/progenitor cells. In: Frontiers in Research vol 1. Georgiev VSt, Westen KA, McGoven JJ (eds). Humana Press 2008, pp. 357-363.
15.  Zuba-Surma EK,  Shin DM, Klich I, Ratajczak J, Kucia M, Ratajczak MZ. Identification of very small embryonic like stem cells from murine and human specimens. In: Applications of Flow Cytometry in Stem Cell Research and Tissue Regenration.(Krishan A, Krishnamutry H and Torey S eds), Willey-Blackwell 2010, pp. 91 -101.
16. Ratajczak MZ, Zuba-Surma E, Kucia M, Nowacki P, Machalinski B. Potential Application of Very Small Embryonic Like (VSEL) Stem Cells in Neural Regeneration. In: Perspectives of Stem Cells From Tools for Studying Mechanisms of Neuronal Differentiation towards Therapy (Ulrich H ed.). Springer 2009, pp. 231-243.
17.  Shin DM, Lui R, Nowacki P, Ratajczak J, M Kucia M, Ratajczak MZ. Very small embryonic-like stem cells and their potential relevance for kidney homeostasis. In: Regenerative Nephrology. (Goligorsky M (ed). Academic Press 2010, pp. 189-199.
18. Shin DM, Klich I, Ratajczak J, Kucia M, Ratajczak MZ. Very small embryonic-like stem cells (VSELs) and importance in growth. In: Handbook of Growth and Growth Monitoring in Health and Disease. (Preedy VR (ed). Springer Science 2012, pp. 1257-1271.
19. Shin DM, Ratajczak J, Kucia M, Ratajczak MZ. Very small embryonic/epiblast-like stem cells (VSELs) residing in adult tissues and their role in tissue rejuvenation and regeneration. In: Embryonic Stem Cells – Differentiation and Pluripotent Alternatives. Intech 2011, pp. 433-450.
20. Ratajczak J, Shin DM, Kucia M, Ratajczak MZ. Very small embryonic-like stem cells from umbilical cord blood. In: Cord Blood, Biology, Transplantation, Banking and regulation. (Broxmeyer H (ed.) AABB Press 2011, pp. 113-131.
21. Ratajczak MZ, Tarnowski M, Borkowska S, Serwin K. The embryonic rest hypothesis of cancer development: 150 years later. In: Trends in Stem Cell Proliferation and Cancer Research. (Resende RR and Ulrich H (eds.) Springer 2013, pp 51-63.

 

ORIGINAL peer-reviewed ARTICLES

1.         Jedrzejczak W.W., Ratajczak M.Z.:  Eosinophilic granulocyte deficiency in mice mutant in sl and w loci.  Experientia 1985, 41, 1596- 1598.  PMID: 3841073
2.         Jedrzejczak W.W., Szczylik C., Ratajczak M.Z., Ahmed A.: Congenital murine osteopetrosis inherited with osteosclerotic (oc) gene: hematological characterization.  Exp. Hematol. 1986, 14, 819 – 826.  PMID: 3758233
3.         Jedrzejczak W.W., Szczylik C., Pojda Z., Siekierzynski M., Kansy J., Klos M., Ratajczak M.Z., Pejcz J., Jaskulski D., Gornas P.: Success of bone marrow transplantation in congenital Diamond – Blackfan anaemia: a case report.  Eur.J.Haemtol. 1987, 38, 204 – 206.  PMID: 3109937
4.         Jedrzejczak W.W., Pojda Z., Ahmed A., Ratajczak M.Z.:  Hematological compensation of microphtalmic mice with congenital osteopetrosis. Bone 1987, 8, 315 – 317.  PMID: 3426889
5.         Ratajczak M.Z., Jaskulski D., Pojda Z., Jedrzejczak W.W.: Omental lymphoid organ as a source of macrophage colony stimulating activity in peritoneal cavity. Clin.Exp.Immunol. 1987, 69, 198 – 203.  PMID: 3498587
6.         Skorski T., Kawalec M., Hoser G., Ratajczak M.Z., Gnatowski B., Kawiak J.: The kinetics of immunologic and hematologic recover in mice after lethal total body irradiation and reconstitution with syngeneic bone marrow cells treated or untreated with mafosfamide (ASTA Z 7654).  Bone Marrow Transplant 1988, 3, 543 – 551.  PMID: 2905613
7.         Ratajczak M.Z.: Evaluation of technical aspects of the preparation of haemopoietic cells from human fetal liver. Arch. Immunol. Ther. Exp. 1988, 36, 223 – 233.  PMID: 3240057
8.         Ratajczak M.Z.: Experimental aspects of transplantation of haemopoietic cells of fetal liver. Arch. Immunol. Ther. Exp. 1988, 36, 235 – 243.  PMID: 2907283
9.         Kaczmarek L., Ratajczak M.Z., Jedrzejczak W.W.: Postirradiation recovery of haemopoiesis in Steel mutant mice.  Int. J. Radiat. Biol. 1988, 53, 703 – 708.  PMID: 3258849
10.      Jedrzejczak W.W., Szczylik C., Matej H., Pojda Z., Ratajczak M.Z.,   Myc  A.,  Siekierzynski M., Kansy J., Klos M., Rybicki Z. et al. Allogeneic bone marrow transplantation from HLA-identical siblings following conditioning with busulfan and cyclophosphamide. First results. Folia Hematol. 1989, 116, 403 – 408.  PMID: 2480281
11.      Ratajczak M.Z., Szczylik C., Jedrzejczak W.W.: Elimination of red blood cells from marrow suspension prior to transplantation using polysaccharide-ditrizoate gradient centrifugation. Experimental studies. Folia. Hematol. 1989, 116, 469 – 473.  PMID: 2480292
12.      Jedrzejczak W.W., Ratajczak M.Z., Szczylik C.: Bone marrow transplantation in Polish conditions. Method for removal of red cells from the transplant in the case of major blood group incompatibility.  Arch. Immunol. Therap. Exp. 1989, 37, 261 – 267.  PMID: 2639626
13.      Ratajczak M.Z., Szczylik C., Berger L.: Assessment of the viability of haemopoietic cells in the livers of mouse fetuses stored at 4 degrees C. Comparison of various methods of testing their usefulness for haemopoietic transplantation. Arch. Immunol.  Therap. Exp. 1989, 37, 269 – 276.  PMID: 2639627
14.      Szczylik C., Ratajczak M.Z., Urbanowska E., Jedrzejczak W.W.:  Kinetics of destruction and regeneration of the haematopoietic system after administration of busulphan and cyclophosphamide followed by bone marrow transplantation. Peripheral blood parameters. Acta Med. Pol. 1989, 30, 93 – 109.  PMID: 2519630
15.      Skorski T., Kawalec M., Ratajczak M.Z., Szczylik C., Kawiak J.: Return of immunohematopoietic impairment a long time after murine syngeneic bone marrow transplantation. Bone Marrow Transplant.1990, 6, 315 – 319.  PMID: 2149830
16.      Ratajczak M.Z.: Values of certain biochemical parameters in mouse serum after syngeneic bone marrow transplantation. Effect of various methods of myeloablation-immunosupression preparation and recipient’s age.  Arch. Immunol. Therap. Exp.1990, 38, 299 – 308.  PMID: 2102662
17.      Calabretta B., Sims R.B., Valtieri M., Caracciolo D., Szczylik C., Venturelli D., Ratajczak M.Z., Beran M., Gewirtz A.: Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an invitro study relevant to bone marrow purging. Proc. Natl. Acad. Sci. USA, 1991, 88, 2351 – 2355.  PMID: 2006173
18.      Skorski T., Ratajczak M.Z., Kawalec M., Kawiak J.: Induction of immune resistance against L1210 lymphatic leukemia in mice after lethal irradiation and reconstitution with fetal liver cells. Folia Histochem. Cytobiol.  1991, 29, 121 – 124.  PMID: 1794437
19.      Jedrzejczak W.W., Szczylik C.,  Matej H.,  Pojda Z., Ratajczak M.Z., Myc A., Siekierzynski M., Kansy J., Klos M., Rybicki Z., Dumanski Z., Zaborowski P., Zaboklicki S., Nowakowska B., Urbanowska E.,  Kuryl J.: Allogeneic bone marrow transplantation from HLA – identical siblings following conditioning with busulphan and cyclophosphamide. Arch. Immunol. Therap. Exp. 1991, 39, 441 – 447.  PMID: 1821620
20.      Ratajczak M.Z., Luger S.M.,  DeRiel K., Abraham J., Calabretta B., Gewirtz A.M.: Role of the KIT protoncogene in normal and malignant  human hematopoiesis.  Proc. Natl. Acad. Sci. USA, 1992, 89, 1710 – 1714.  PMID: 1371882
21.      Skorski T., Szczylik C., Ratajczak M.Z., Malaguarnera L., Gewirtz A.M., Calabretta B.: Growth factor – dependent inhibition of normal hematopoiesis by N-ras antisense oligodeoxynucleotides. J. Exp. Med. 1992, 175, 743 – 750.  PMID: 1371302
22.      Ratajczak M.Z., Hijiya N., Catani L., DeRiel K., Luger S.M., McGlave Ph., Gewirtz A.:  Acute- and Chronic- Phase Myelogenous Leukemia Colony-Forming Units are highly sensitive to the growth inhibitory effects of c-myb antisense oligodeoxynucleotides. Blood 1992, 79, 1956 – 1961.  PMID: 1562723
23.      Gewirtz A.M., Boghosian-Sell L., Catani L., Ratajczak M.Z., Shen Y.M. Expression of FcRII and CD4 receptors by normal human megakaryocytes. Exp. Hematol 1992, 20, 512-516.  PMID: 1533189
24.      Ratajczak M.Z., Luger S.M., Gewirtz A.M.: The role of c-kit protoncogene in normal and malignant human hemopoiesis. (Concise  Review). Int. J. Cell Clon. 1992, 10, 205-214.  PMID: 1379619
25       Jedrzejczak W.W., Ratajczak M.Z., Ptasznik A., Sell K.W., Ahmed A. A., Ostertag W.:  CSF-1 deficiency in the op/op mouse has differential effects on macrophage populations and differentiation stages. Exp. Hematol. 1992, 20, 1004 – 1010.  PMID: 1505635
26.      Ratajczak M.Z., Kant J.A., Hijiya N., Luger S.M., Zhang J., Zon G., Gewirtz A. M.:  In vivo treatment of human leukemia in a SCID mouse model with c-myb antisense oligodeoxynucleotides.  Proc. Natl. Acad. Sci. USA, 1992, 89, 11823-11827.  PMID: 1281545
27.      Takeshita K., Bollekens J.A., Hijiya N., Ratajczak M.Z., Ruddle F., Gewirtz A.M.: A homeobox gene of the Antennapedia class is required for human adult erythropoiesis. Proc. Natl Acad. Sci. USA 1993, 90, 3535 – 3538.  PMID: 8097318
28.      Ratajczak M.Z., Light B., Ratajczak J., Kuczynski W.I., Gewirtz A.M.: Human erythropoiesis in vitro: definition, and clinical  implications, of optimal stimulatory conditions.  Cancer Res. Ther. Cont. 1993, 3, 269 – 272.
29.      Ratajczak M.Z., Skorski T., Kuczynski W., Ratajczak J.: The influence of 4oC storage on proliferative potential of human bone marrow CD34+ cells. Transplantological implications. Folia Histochem. Cytobiol. 1993, 3, 109 -112.  PMID: 7505239
30.      Migliaccio A.R., Migliaccio G., Mancini G., Ratajczak M., Gewirtz A.M., Adamson J.W.: Induction of the murine „W phenotype” in long-term cultures of human cord blood cells by c-kit antisense oligomers. J. Cell. Physiol. 1993, 157, 158-163.  PMID: 7691834
31.      Ratajczak M.Z., Ratajczak J., Kuczynski W., Light B., Gewirtz A.M.: In vitro sensitivity of human hemopoietic progenitor cells to 4-Hydroperoxycyclophosphamide. Exp. Hematol 1993, 21, 1663 – 1667.  PMID: 8243568
32.      Small D., Levenstein M., Kim E., Carow C., Amin S., Rockwell P., Witte L., Burrow Ch., Ratajczak M.Z., Gewirtz A.,M., Civin C.I.: STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells. Proc. Natl. Acad. Sci. USA 1994, 91, 459-463.  PMID: 7507245
33.      Skorski T., Palanisamy K., Skorska M., Ratajczak M., Szczylik C., Zon G, Arlinghaus R., Gewirtz A., Perussia B., Calabretta B.: p210 GAP requirement in normal and malignant human hematopoiesis. J. Exp. Med. 1993, 178, 1923-1933.  PMID: 8245773
34.      Ratajczak M.Z., Kuczynski W.I., Ratajczak J.: The influence of different cryopreservation procedures on the proliferative potential of human bone marrow progenitor cells. Transplantological implications. Arch. Immunol. Therap. Exp. 1994, 42, 217 – 221.  PMID: 7487356
35.      Hijiya N., Zhang J., Ratajczak M.Z., DeRiel K., Herlyn M., Gewirtz A.M.: The biologic and therapeutic significance of c-Myb expression in human melanoma.  Proc. Natl. Acad. Sci. USA 1994, 91, 4499-4503.  PMID: 8183937
36.      Kuczynski W.I., Ratajczak M.Z.: STK-1 receptor gene is expressed in the various human non-hematopoietic tumor cell lines – RT-PCR directed analysis of STK-1 mRNA expression. Preliminary report. Acta Haematol. Pol. 1994, 25, 43-46.  PMID: 8209613
37.      Skorska-Nieborowska M., Skorski T, Ratajczak M.Z., Szczylik C., Malaguarnera L, Calabretta B.: Successful mafosfamide purging of bone marrow from chronic myelogenous leukemia (CML) cells. Folia Histochem. Cytobiol. 1993, 31, 161 – 167.  PMID: 8137996
38.      Nieborowska M., Skorski T., Nakashima M., Ratajczak M.Z., Steplewski Z., Calabretta B.: Oncogene-targeted antisense oligodeoxynucleotides combined with chemotherapy or immunotherapy: a new approach for tumor treatment. Folia Histochem. Cytobiol. 1994, 32, 35-40.  PMID: 8026602
39.      Ratajczak M.Z., Kuczynski W.I., Skorski T., Ratajczak J.:  Pre-stimulation of the human bone marrow CD34+ cells before storage at 4°C with the early acting cytokines enhance their survival and increase proliferative potential. Transplantological implications. Mater. Med. Pol. 1993, 3-4, 133 – 136.  PMID: 7520961
40.      Ratajczak M.Z., Ratajczak J., Kregenov D., Kuczynski W., Skorski T., Gewirtz A.M.: Cytokine stimulation of the CD34+ bone marrow cells prior to cryopreservation enhances their post-thawing proliferative potential. Folia. Histochem. Cytobiol. 1994, 3, 145 – 149.  PMID: 7531164
41.      Ratajczak M.Z., Kuczynski W.I., Onodera K., Moore J., Ratajczak J., Kregenov A.A., DeRiel K., Gewirtz A.M.:  A reappraisal of the function of the insuline like growth factor -1 (IGF – 1) in the  regulation of the human hematopoiesis. J. Clin. Invest.  1994, 94, 320 – 327.  PMID: 8040273
42.      Ratajczak M.Z., Kregenov D.A, Gewirtz A.M.: The storage of the cells from different tumor lines in the mechanical freezer at -80oC. Comparison to cryopreservation in liquid nitrogen. Mat. Med. Pol. 1994,  2, 69 – 72.  PMID: 7745987
43.      Ratajczak M.Z., Ratajczak J., Kregenow D., Gewirtz A.M.: Growth factor stimulation of cryopreserved CD34+ bone marrow cells for transplant. An in vitro study to determine optimal timing of exposure to early acting cytokines. Stem Cells 1994,  12, 599 – 603.  PMID: 7533578
44.      Nieborowska-Skorska M., Ratajczak M.Z., Calabretta B., Skorski T.: The role of c-myc protooncogene in CML. Folia Histochem. Cytobiol. 1994, 32, 231-234.  PMID: 7758616
45.      Morrow D.M., Xiong N., Getty R.R., Ratajczak M.Z., Morgan D., Seppala M., Rittinen L., Gewirtz A.M., Tykocinski M.L.: Hematopoietic placental protein-14 an immunosuppressive factor in cells of the megakaryocytic lineage. Am. J. Pathol. 1994, 145, 1485-1495.  PMID: 7992851
46.      Skorski T., Kanakaraj P., Nieborowska-Skorska M., Ratajczak M.Z., Wen S.C., Zon G., Gewirtz A.M., Perussia B., Calabretta B.: Phosphatidylinositol-3 kinase activity is regulated by bcr/abl and is required for the growth of Philadelphia chromosome-positive cells. Blood 1995, 86, 726-736.  PMID: 7606002
47.      Ratajczak M.Z., Gewirtz A.M.: The biology of hemopoietic stem cells. Semin. Oncol. 1995, 22, 210-217.  PMID: 7777865
48.      Ratajczak M.Z., Kuczynski W.I., Sokol L.D., Moore J., Pletcher, C.,  Gewirtz A.M.: Expression, and physiologic significance, of Kit Ligand and Stem Cell Tyrosine Kinase-1 Receptor Ligand in normal human CD34+, C-Kit R+ marrow cells. Blood 1995, 86, 2161 – 2167.  PMID: 7545021
49.      Gewirtz A.M., Zhang J., Ratajczak J., Ratajczak M.Z., Park K.S., Li C., Yan Z., Poncz M.: Chemokine regulation of human megakaryocytopoiesis. Blood, 1995, 86, 2559 – 2567.  PMID: 7670101
50.      Luger S.M., Ratajczak J., Ratajczak M.Z.,  DiPaola R., Clevenger R., Gewirtz A.M.: Role of the p95vav  protooncogene in normal and malignant human hematopoiesis. Blood 1996, 87, 1326-1334.  PMID: 8608221
51.      Ratajczak M.Z., Ratajczak J., Ford J., Kregenow R., Marlicz W., Gewirtz A.M.: FLT3/FLK-2 (STK-1) ligand does not stimulate human megakaryopoiesis in vitro.  Stem Cells 1996, 14, 147-150.  PMID: 8820960
52.      Ratajczak M.Z., Gewirtz A.M.: Current experimental strategies for investigating human hematopoietic stem cell biology. (Editorial Review). Folia Histochem. Cytobiol. 1996, 34, 59-67.  PMID: 8875212
53.      Calabretta B., Skorski T., Ratajczak M.Z., Gewirtz A.M.: Antisense strategies in the treatment of leukemias. Seminars in Oncology 1996, 23, 78-87.  PMID: 8607034
54.      Ratajczak M.Z., Ratajczak J., Skorska M., Calabretta B., Pletcher Ch.J., Marlicz W., Moore J., Gewirtz A.M.: Effect of basic (FGF-2) and acidic (FGF-1) fibroblast growth factors on early hematopoietic cell development. Brit. J. Haematol.  1996, 93, 772-782.  PMID: 8703802
55.      Ratajczak J., Marlicz W., Keidel A., Machalinski B., Ratajczak M.Z, Gewirtz A.M.: In vitro studies on the anemia of chronic inflammatory disorders. Effect of Interleukin-1a and interleukin-1a on erythroid progenitor cell growth in serum free cultures: An in vitro study relevant to the pathogenesis of the anemia of chronic disease. Hematology 1997, 2, 21-28.  PMID: 10907020
56.      Ratajczak M.Z., Gewirtz A.M.: Hematopoietic stem cells. Helix 1997, 6, 4-9.
57.     Ratajczak J., Machalianski B., Marlicz W., Halasa M., Ratajczak M.Z.: Influence of leukemia inhibitory factor (LIF) on the survival, proliferation, and differentiation of human erythroid progenitor cells. In vitro studies under serum free conditions. Folia Histochem. et Cytobiol. 1997, 35, 63-68.  PMID: 9151079
58.      Ratajczak J., Marlicz W., Rozmyslowicz T., Machalinski B., Ratajczak M.Z.: Comparison of the different strategies for cryopreserving and storage of the bone marrow CD34+ cells. Possibility of uncontrolled rate freezing and storage at -80oC mechanical freezer. Ann. Transplant. 1997, 1, 35-38.  PMID: 9869904
59.      Ratajczak M.Z.: Fibroblast growth factors and early hemopoietic cell development. Leukemia & Lymphoma 1997, 27, 221-229.  PMID: 9402321
60.      DiPaola R.S.,  Kuczynski W., Onodera K., Ratajczak M.Z., Hijiya N.,  Moore J.,  Gewirtz A.: Evidence for a Functional Kit Receptor in Melanoma, Breast and Lung Carcinoma Cells. Cancer & Gene Ther. 1997, 4, 176-182.  PMID: 9171936
61.      Ratajczak M.Z., Ratajczak J., Marlicz W., Pletcher Ch.H., Moore J., Hung H., Gewirtz A.M.: Recombinant human thrombopoietin (TPO) stimulates erythropoiesis by inhibiting erythroid progenitor cell apoptosis. Brit. J. Haematol. 1997, 98, 8-17.  PMID: 9233556
62.      Ratajczak M.Z., Ratajczak J., Kregenow D.A., Marlicz W., Machalinski B., Simon M., Luger S., Gewirtz A.M.: An optimization study on unprogrammed cryopreservation of human CD34+ bone marrow cells and their subsequent storage in an -80oC mechanical freezer. Ann. Transpl. 1997, 2, 5-11.  PMID: 9869847
63.      Ratajczak M.Z., Marlicz W., Ratajczak J., Machalinski B., Wasik M., Carter A., Gewirtz A.M.: Effect of hepatocyte growth factor (HGF) on human early haematopoietic cell development. Brit. J. Haematol. 1997, 99, 228-236.  PMID: 9359529
64.      Ratajczak M.Z., Ratajczak J., Machalinski B., Mick R., Gewirtz A.M.: In vitro and in vivo evidence that ex vivo cytokine priming of donor marrow cells may ameliorate post-transplant thrombocytopenia. Blood 1998, 91, 353-359.  PMID: 9414305
65.      Ratajczak M.Z., Perrotti D., Meloti P., Powzaniuk M., Calabretta B., Onodera K., Kregenow D.A., Machalinski B., A.M. Gewirtz.: Myb and Ets proteins are candidate regulators of c-kit expression in human hematopoietic cells.  Blood 1998, 91, 1934-1946.  PMID: 9490676
66.      Ratajczak J., Marlicz W. Machalinski B., Pertusini E., Czajka R., Ratajczak MZ.: An improved serum free system for cloning human „pure” erythroid colonies. The role of the different growth factors and cytokines on BFU-E formation by the bone marrow and cord blood CD34+ cells. Folia Histochem. et Cytobiol. 1998, 36, 61-66.  PMID: 9606618
67.      Ratajczak J., Machalinski B., Samuel A., Pertusini E., Majka M., Czajka R., Ratajczak M.Z.: A novel serum free system for cloning human megakaryocytic progenitors (CFU-Meg): The role of thrombopoietin and other cytokines on bone marrow and cord blood CFU-Meg growth under serum free conditions. Folia Histochem. et Cytobiol. 1998, 36, 55-60.  PMID: 9606619
68.      Ratajczak J., Zhang Q, Wojczyk S., Pertusini E., Wasik M, Ratajczak M.Z.: The role of insulin, and insulin like growth factor-I in regulating human erythropoiesis. Studies in vitro under serum free conditions – comparison to other cytokines and growth factors. Leukemia 1998, 12, 371-381.  PMID: 9529132
69.      Ratajczak M.Z., Plecher Ch. H., Marlicz W., Machalinski B., Moore J., Wasik M., Ratajczak J., Gewirtz A.M.: CD34+, Kit+, Rhodamine123low phenotype identifies a marrow cell population highly enriched for human hematopoietic stem cells. Leukemia.  1998, 12, 942-950.  PMID: 9639424
70.      Parker R.I., Siegel R.S., Ratajczak M.Z., Gewirtz A.M.: Deficient in vitro megakaryocytopoiesis and decreased in vivo platelet turnover in children and young adults with chronic thrombocytopenia. J. Ped. Hem. & Oncol. 1998, 20, 196-201.  PMID: 9628429
71.      Wlodarski P., Wasik M., Ratajczak M.Z., Sevignani C., Hoser G., Kawiak J., Gewirtz A.M., Calabretta B., Skorski T.: Role of p53 in hematopoietic recovery after cytostatic treatment. Blood 1998, 91, 2998-3006.  PMID: 9531612
72.      Lee B., Dornkranz B.J, Ratajczak M.Z., Doms B.W.: An intricate web: chemokine receptors, HIV-1, and hematopoiesis.  Stem Cells 1998, 16, 79-88.  PMID: 9554031
73.      Gewirtz A.M., Sokol D.L., Ratajczak M.Z.: Nucleic acid therapeutics: State of the art and future prospects.  Blood 1998, 92, 712-736.  PMID: 9680338
74.      Ratajczak M.Z., Ratajczak J., Machalinski B., Majka M., Marlicz W., Carter A., Pietrzkowski Z., Gewirtz A.M.: Role of vascular endothelial growth factor (VEGF), placenta derived growth factor (PlGF)/Flt-1 and Flk-1/KDR receptor axes in human adult and fetal hematopoiesis. Brit. J. Haematol.  1998, 103, 969-979.  PMID: 9886308
75.     Machalinski B., Zejmo M., Stecewicz I., Machalinska A, Machoy Z., Ratajczak MZ.:  The influence of sodium fluoride on the clonogenecity of the human hematopoietic progenitor cells. Preliminary report.  Fluoride 2000, 4, 174-179.
76.      Kowalska M.A., Ratajczak J., Hoxie J., Brass L., Gewirtz A.M., Poncz M., Ratajczak M.Z.: Platelet and megakaryocytes express the HIV co-receptor CXCR4 on their surface but do not respond to stromal derived factor (SDF) – 1. Brit. J. Haematol. 1999, 104, 220-229.  PMID: 10050701
77.      Machalinski B., Wiszniewska B., Balcewicz M., Marchlewicz M., Majka M., Wenda-Rozewicka L, Ratajczak MZ.: In vivo and in vitro studies on the toxicity of Hoechst 33342 (Ho342). Implications for employing Ho342 for the isolation of the hematopoietic stem cells. Annals of Transpl. 1998, 3, 5-13.  PMID: 10234429
78.      Lee B., Ratajczak J, Doms RW, Gewirtz AM, Ratajczak MZ.: Coreceptor/chemokine receptor expression on human hematopoietic cells: Biological implications for HIV-1 infection. Blood 1999, 93, 1145-1156.  PMID: 9949156
79.      Zent CS, Ratajczak J, Ratajczak MZ, Anastasi J, Hoffman PC, Gewirtz AM:  Relationship between megakaryocyte mass and serum thrombopoietin levels as revealed by a case of cyclic amegakaryocytic thrombocytopenia purpura. Brit. J. Haematol. 1999, 105, 452-458.  PMID: 10233421
80.      Marlicz W., Paczkowski M., Kijowski J., Machalinski B., Gontarewicz A., Paczkowska E., Zukowski M., Bohatyrewicz R., Czajkowski Z., Ostrowski M. Ratajczak MZ: Isolation of the hematopoietic stem cells (HSC) from the heparinized cadaveric multiple organ donors (HCMOD). Potential clinical implications. Transpl. Proceedings 1999, 31, 2099-2101.  PMID: 10455982
81.      Ratajczak J, W, Machalinski B, Majka M, Kijowski J, Marlicz Rozmyslowicz T, Ostrowski M, Ratajczak MZ: Evidence that human haematopoietic stem cells (HSC) do not reside within the CD34+KIT- cell population. Annals of Transplant. 1999, 4, 23-31.  PMID: 10850597
82.      Honczarenko M, Douglas RS, Mathias C, Lee B, Ratajczak MZ, Silberstein LE.: SDF-1 responsiveness does not correlate with CXCR4 expression levels of developing human bone marrow B cells. Blood 1999, 94, 2990-2998.  PMID: 10556181
83.      Machalinski B, Szolomicka P, Baskiewicz M, Karbicka A, Kijowski J, Byra E, Majka M, Giedrys-Kalemba S, Ratajczak M.Z.: Short-term storage of human hematopoietic cells. Influence of the air and deoxyribonuclease I. Annals of Transplant. 1999, 4, 29-36.  PMID: 10850588
84.      Majka M, Ratajczak J, Kowalska MA, Ratajczak MZ.: Binding of stromal derived factor-1a (SDF-1a) to CXCR4 chemokine receptor in normal human megakaryoblasts but not in platelets induces phosphorylation of mitogen-activated protein kinase p42/44 (MAPK), ELK-1 transcription factor and serine/threonine kinase AKT. Eur. J. Haematol. 2000, 64, 164-172.  PMID: 10997882
85.      Majka M, Ratajczak J, Machalinski B, Carter A, Pizzini D, Wasik MA, Gewirtz AM, Ratajczak MZ: Expression, regulation, and function of AC133, a putative cell surface marker of primitive human haematopoietic cells. Folia Histochem. et Cytobiol. 2000, 38, 53-63.  PMID: 10833669
86.      Majka M, Rozmyslowicz T, Lee B, Pietrzkowski Z, Gaulton GN, Silberstein L, Ratajczak MZ.: Bone Marrow CD34+ cells and megakaryoblasts secrete -chemokines; implications for infectability by M-tropic human immunodeficiency virus (R5 HIV). J. Clin. Invest. 1999, 104, 1739-1749.  PMID: 10606628
87.      Kowalska, M.A., Ratajczak, M.Z., Majka, M., Brass, L.W., Poncz, M.: SDF-1 and MDC: complementary chemokines at the crossroads between inflammation and thrombosis. Blood 2000, 96, 50-57.  PMID: 10891429
88.      Majka M, Ratajczak J, Lee B, Honczarenko M, Douglas R, Kowalska MA, Silberstein L, Gewirtz AM, Ratajczak MZ: The role of HIV related chemokine receptors and chemokines in human erythropoiesis in vitro.  Stem Cells 2000, 18, 128-138.  PMID: 10742385
89.      Majka M, Rozmyslowicz T, Honczarenko M, Ratajczak J, Wasik M, Gaulton GN, Ratajczak MZ.:  Biological significance of the expression of HIV related chemokine coreceptors (CCR5 and CXCR4) and their ligands by human hematopoietic cell lines. Leukemia 2000, 14, 1821-1832.  PMID: 11021758
90.      Janowska-Wieczorek A,  Marquez LA,  Dobrowsky A, Ratajczak MZ, Cabuhat ML. Differential MMP and TIMP production by human marrow and blood CD34+ cells in response to chemokines. Exp. Hematol. 2000, 28, 1274-1285.  PMID: 11063876
91.      Majka M, Rozmyslowicz T, Ratajczak J, Dobrowsky A, Pietrzkowski Z, Gaulton GN, Janowska-Wieczorek A, Ratajczak MZ.: The limited infectability by R5 HIV of CD34+ cells from thymus, cord and peripheral blood and bone marrow is explained by their ability to produce -chemokines. Exp. Hematol. 2000, 28, 1334-1342.  PMID: 11146155
92.      Majka M,  Janowska-Wieczorek A, Ratajczak J,  Kowalska MA,  Vilaire G, Pan ZK, Honczarenko M,  Marquez LA,  Poncz M,  Ratajczak MZ.: Stromal Derived Factor-1 and Thrombopoietin Regulate Distinct Aspects of Human Megakaryopoiesis. Blood, 2000, 96, 4142-4151.  PMID: 11110685
93.      Pertussini E, Ratajczak J, Majka M, Vaughan D, Ratajczak M.Z, Gewirtz AM.: Investigating the platelet sparing mechanism of Paclitaxel/Carboplatin combination chemotherapy. Blood 2001, 97, 638-644.  PMID: 11157479
94.      Janowska-Wieczorek A, Majka M, Ratajczak J, Ratajczak MZ.: Autocrine/paracrine mechanisms in human hematopoiesis. Stem Cells 2001, 19, 99-107.  PMID: 11239164
95.      Machalinski B, Kijowski J, Marlicz W, Gontarewicz A, Markiewski M, Paczkowski M, Kopkowski A, Majka M, Ostrowski M, Ratajczak M.Z.: Heparinized cadaveric organ donors (HCOD) – a potential source of hematopoietic cells from transplantation and gene therapy. Transplantation 2001, 71, 1003-1007.  PMID: 11349709
96.      Majka M, Janowska-Wieczorek A, Ratajczak J, Ehrenman K, M.A. Kowalska, Gewirtz AM, Emerson SG, Ratajczak MZ. Numerous growth factors, cytokines and chemokines are secreted by human CD34+ cells, myeloblasts, erythroblasts and megakaryoblasts and regulate normal hematopoiesis in an autocrine/paracrine manner. Blood 2001, 97, 3075-3085.  PMID: 11342433
97.      Majka M, Ratajczak J, Baj M, Kijowski J, Reca R, Kubiczek K, Ratajczak MZ.: Biological significance of chemokine receptors expression by normal human megkaryoblasts. Folia Histochem. et Cytobiol 2001, 39, 235-244.  PMID: 11534779
98.      Majka M, Baj M, Kijowski J, Reca R, Ratajczak J,  Ratajczak MZ.: In vitro expansion of human megakaryocytes as a tool for studying megakaryocytic development and function.  Platelets 2001, 12, 325-332.  PMID: 11672471
99.      Kijowski J, Baj M, Majka M, Reca R, Marquez LA, Christofidou-Solomidou M, Janowska-Wieczorek A, Ratajczak MZ.: The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but boes not affect proliferation and survival in lymphohematopoietic cells. Stem Cells 2001, 19, 453-466.  PMID: 11553854
100.    Ratajczak J,  Majka M, Kijowski J,  Baj M,. Pan ZK, Marquez LA, Janowska-Wieczorek A, Ratajczak MZ.: Biological significance of MAPK, AKT and JAK-STAT protein activation by various erythropoietic factors in normal human early erythroid cells. Brit. J. Haematol. 2001, 114, 195-205.  PMID: 11722433
101.    Janowska-Wieczorek A, Majka M, Kijowski J, Baj-Krzyworzeka M, Reca R, Turner AR, Ratajczak J, Kowalska MA, Ratajczak MZ.:  Platelet-derived microparticles (PMPs) bind to hematopoietic stem/progenitor cells (HSPC) and enhance their engraftment. Blood 2001, 98, 3143-3149.  PMID: 11698303
102.    Rozmyslowicz T, Kijowski J, Conover DO, Majka M, Baj-Krzyworzeka M, Reca R, J. Libura, Gaulton GN, Ratajczak MZ.:  The role of selected intrinsic factors in the infectability of T-lymphocytic cell lines by HIV.  Eur. J. Haematol. 2001, 67, 142-151.  PMID: 11737246
103.    Marquez LA, Dobrowsky A, Montano J, Turner AR, Ratajczak J, Ratajczak MZ, Janowska-Wieczorek A.: Matrix metalloproteinase and tissue inhibitors of metalloproteinase secretion by haematopoietic and stromal precursors and their production in normal and leukaemic long-term marrow cultures. Brit. J. Haematol. 2001, 115, 595-604.  PMID: 11736941
104.    Luger SM, O’Brien SG, Ratajczak J, Ratajczak MZ, Mick R, Stadmauer EA, Nowell PC, Goldman JM, Gewirtz AM.: Oligodeoxynucleotide-mediated inhibition of c-myb gene expression in autografted bone marrow: a pilot study. Blood 2002, 99, 1150-1158.  PMID: 11830460
105.    Machalinski B, Gontarewicz A, Ratajczak MZ.: Morphological analysis of the bone marrow biopsies derived from heparinized cadaveric organ donors before and after disconnecting from the respirator. Annals of Transplant. 2002, 4, 48-52.  PMID: 12035459
106.    Janowska-Wieczorek A, Majka M, Marquez-Curtis L, Wertheim JA, Turner AR, Ratajczak MZ.: Bcr-abl-positive cells secrete angiogenic factors including matrix metalloproteinases and stimulate angiogenesis in vivo in matrigel implants. Leukemia 2002, 16, 1160-1166.  PMID: 12040448
107.    Baj-Krzyworzeka M, Majka M, Pratico D, Ratajczak J, Vilaire G, Kijowski J, Reca R, Janowska-Wieczorek A, Ratajczak MZ.: Platelet-derived microparticles stimulate proliferation, survival, adhesion and chemotaxis of hematopoietic cells. Exp. Hematol. 2002, 30, 450-459.  PMID: 12031651
108.   Majka M, Ratajczak J, Villaire G, Kubiczek K, Marquez LA, Janowska-Wieczorek A, Ratajczak MZ.:  Thrombopoietin, but not cytokines binding to gp130 protein-coupled receptors, activates MAPKp42/44, AKT and STAT proteins in normal human CD34+ cells, megakaryocytes and platelets. Exp. Hematol. 2002, 30, 751-760.  PMID: 12135673
109.    Honczarenko M, Glodek AM, Majka M, Campbell JJ, Ratajczak MZ, Siberstein LE.: CCR5 binding chemokines modulate CXCL12(SDF-1) induced responses of progenitor B cells in human bone marrow through heterologous desensitization of the CXCR4 chemokine receptor. Blood 2002, 100, 2321-2329.  PMID: 12239139
110.    Libura J, Drukala J, Majka M, Tomeascu O, Navenot JM, Kucia M, Marquez L, Peiper SC, Barr FG, Janowska-Wieczorek A, Ratajczak MZ.: CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis and adhesion. Blood 2002,100, 2597-2606.  PMID: 12239174
111.    Ratajczak J, Kijowski J, Majka M, Jankowski K, Reca R, Ratajczak MZ.: Biological significance of the different erythropoietic factors secreted by normal human early erythroid cells. Leukemia & Lymphoma 2003, 44, 767-774.  PMID: 12802912
112.    Rozmyslowicz T, Majka M, Kijowski J, Murphy SL, O’Connover D, Poncz M, Ratajczak J, Gaulton GN, Ratajczak MZ.: Platelet- and megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV. AIDS 2003, 17, 33-42.  PMID: 12478067
113.    Wang ZY, Zhang Q, Wilson J, Ratajczak MZ, Wasik MA: Detection of protein
tyrosine-kinase (PTK) gene expression pattern in normal and malignant T
lymphocytes by combined PTK-specific PCR and parallel denaturing gradient
gel electrophoresis (DGGE). J. Molec. Diagn. 2003, 5, 113-120.  PMID: 12707376
114.    Pituch-Noworolska A, Majka M, Janowska-Wieczorek A , Monika Baj, Urbanowicz B, Malec E,  Ratajczak MZ.: Circulating CXCR4-positive stem/progenitor cells compete for SDF-1 positive niches in bone marrow, muscle and neural tissues: An alternative hypothesis to stem cells plasticity. Folia Histochem. et Cytobiol. 2003, 41, 13-21.  PMID: 12705474
115.   Reca R, Mastellos D, Majka M, Marquez L, Ratajczak J, Franchini S, Glodek A, Honczarenko M, Spruce LA, Janowska-Wieczorek A, Lambris JD, Ratajczak MZ.: Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells and C3a enhances homing-related responses of early hematopoietic cells to SDF-1. Blood 2003, 101, 3784-3793.  PMID: 12511407
116.    Ratajczak MZ, Majka M, Kucia M, Drukala J, Pietrzkowski Z, Peiper S, Janowska-Wieczorek A.: Expression of functional CXCR4 by muscle satellite cells and secretion of SDF-1 by muscle-derived fibroblasts is associated with the presence of both muscle progenitors in bone marrow and hematopoietic stem/progenitor cells in muscles. Stem Cells 2003, 21, 363-371.  PMID: 12743331
117.    Ratajczak J, Kucia M, Reca R, Zhang J, Machalinski B, Ratajczak M.Z.:  Quiescent CD34+ early erythroid progenitors are resistant to several erythropoietic „inhibitory” cytokines; role of FLIP. Brit. J. Haematol. 2003, 123, 160-169.  PMID: 14510960
118.  Kucia M, Ratajczak J, Reca R, Janowska-Wieczorek A, Ratajczak M.Z.: Tissue-specific Muscle, Neural and Liver Stem/Progenitor Cells Reside in the Bone Marrow, Respond to an SDF-1 Gradient and Are Mobilized into Peripheral Blood during Stress and Tissue Injury. Blood Cells Mol. Dis. 2004, 32, 52-7.  PMID: 14757413
119.    Jankowski K, Kucia M, Wysoczynski M, Reca R, Zhao D, Trzyna E, Zembala M, Ratajczak J, Houghton P,  Janowska-Wieczorek A,  Ratajczak M.Z.: Both HGF and SDF-1 Regulate the Metastatic Behavior of Human Rhabdomyosarcoma Cells, but only HGF Enhances their Resistance to Radio-chemotherapy. Cancer Res. 2003, 63, 7926-7935.  PMID: 14633723
120.    Kucia M, Wysoczynski M, Reca R, Jankowski K, Bandura L, Allendorf DJ, Zhang J, Ratajczak J, Ratajczak M.Z.: CXCR4-SDF-1 signaling, locomotion, chemotaxis and adhesion. Journal of Molecular Histology 2004, 35, 233-245.  PMID: 15339043
121.    Ratajczak M.Z., Kucia M, Reca R, Majka M, Janowska-Wieczorek A, Ratajczak J.: Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells „hide out” in the bone marrow. Leukemia 2004, 18, 29-40.  PMID: 14586476
122.    Ratajczak J, Reca R, Kucia M, Majka M, Allendorf DJ, Baran JT, Janowska-Wieczorek A, Wetsel RA, Ross GD, Ratajczak M.Z.: Mobilization Studies in Mice Deficient in Either C3 or C3a-Receptor (C3aR) Reveal a Novel Role For Complement in Retention of Hematopoietic Stem/Progenitor Cells in Bone Marrow. Blood 2004, 103, 2071-2078.  PMID: 14604969
123.    Ratajczak M.Z., Kucia M, Majka M, Reca R, Ratajczak J. Heterogenous populations of bone marrow stem cells – are we spotting on the same cells from the different angles? Folia Histochem. et Cytobiol 2004, 42, 139-146.  PMID: 15493574
124.    Ratajczak M.Z., Reca R, Wysoczynski M, Kucia M, Baran JT, Allendorf DJ, Ratajczak J, Ross GD. Transplantation studies in C3-deficient animals reveal a novel role of the third complement component (C3) in engraftment of bone marrow cells. Leukemia 2004, 18, 1482-1490.  PMID: 15284858
125.    Kucia M, Ratajczak J, Ratajczak MZ. Bone Marrow as a Source of Circulating CXCR4+ Tissue Committed Stem Cells (TCSC). Biol. Cell 2005, 97, 133-146.  PMID: 15656779
125.    Janowska-Wieczorek A, Wysoczynski M, Kijowski J, Marques-Curtis L, Machalinski B, Ratajczak J, Ratajczak M.Z. Microvesicles Derived from Activated Platelets Induce Metastasis and Angiogenesis in Lung Cancer. Int J Cancer 2005, 113, 752-760.  PMID: 15499615
126.    Wysoczynski M, Reca R, Ratajczak J, Kucia M, Shirvaikar N, Mills M, Wanzeck J, Honczarenko M, Janowska-Wieczorek A, Ratajczak M.Z. Incorporation of CXCR4 into Membrane Lipid Rafts Primes Homing-related responses of Hematopoietic Stem Cells to an SDF-1 Gradient. Blood 2005, 105, 40-48.  PMID: 15328152
127.    Wojakowski W, Tendera M,  Michalowska A, Majka M, Kucia M, Maslankiewicz K, Wyderka R, Ochala A, Ratajczak M.Z. The mobilization od CD34+/CXCR4+, CD34+/CD117+, c-Met+ stem cells and mononuclear cells expressing early cardiac, muscle and endothelial markers into peripheral blood in patients with acute myocardial infarction. Circulation 2004, 110, 3213-3220.  PMID: 15533859
128.    Chilton PM, Rezzoug F, Ratajczak M.Z., Fugier-Vivier I, Ratajczak J, Kucia M, Huang, Tanner MK, Ildstad ST Hematopoietic stem cells from NOD mice exhibit autonomous behavior and a competitive advantage in allogeneic recipients Blood 2005, 105, 2189-2197.  PMID: 15522953
129.    Barcew K, Karbicka A,  Wiszniewska B,  Ratajczak M.Z., Machaliński B.  Effect of stem cell mobilization with cyclophosphamide and G-CSF on morphology of hematopoietic organs in mice. Cell Proliferation 2005, 38, 47-61.  PMID: 15679866
130.    Kucia M, Dawn D, Hunt G, Guo Y, Wysoczynski M,  Majka M,  Ratajczak J, Rezzoug F, Ildstad ST,  Bolli R,  Ratajczak M.Z. Cells expressing markers of cardiac tissue-committed stem cells reside in the bone marrow and are mobilized into peripheral blood following myocardial infraction. Cir. Research 2004, 95, 1191-1199.  PMID: 15550692
131.    Kucia M, Ratajczak J, Ratajczak M.Z. Are Bone marrow stem cells plastic or heterogenous – that is the question. Exp. Hematol. 2005, 33, 613-623.  PMID: 15911085
132.    Kucia M, Reca R, Miekus K, Wanzeck J, Wojakowski W, Janowska-Wieczorek A, Ratajczak J,  Ratajczak M.Z. Trafficking of Normal Stem Cells and Metastasis of Cancer Stem Cells Involve Similar Mechanisms: Pivotal Role of  the SDF-1–CXCR4 Axis. Stem Cells 2005, 23, 879-894.  PMID: 15888687
133.  Kucia M, Reca R, Jala VR, Dawn B, Ratajczak J, Ratajczak M.Z. Bone marrow as a home of heterogenous populations of nonhematopoietic stem cells. Leukemia 2005, 19, 1118-1127.  PMID: 15902288
134.   Ratajczak M.Z., Reca R., Wysoczynski M. Response to „C5L2 Receptor is not Involved in C3a/C3a-desArg Mediated Enhancement of Bone Marrow Hematopoietic Cell Migration to CXCL12” by Honczarenko et al. Leukemia 2005, 19, 1685-1686.
135.  Opalinska JB, Machalinski B, Ratajczak J, Ratajczak MZ, Gewirtz AM. Multi-Gene Targeting with Antisense Oligodeoxynucleotides:  An Exploratory Study Employing Primary Human Leukemia Cells. Clin Cancer Res 2005, 11, 4948-4954.  PMID: 16000594
136.   Majka M, Kucia M, Ratajczak MZ. Stem cell biology – a never ending quest for understanding. Acta Biochem. Pol. 2005, 52, 353-358.  PMID: 15990920
137.   Paczkowska E, Larysz B, Rzeuski R, Karbicka A, Jałowiński R, Kornacewicz-Jach Z, Ratajczak M.Z, Machaliński B. Human hematopoietic stem/progenitor-enriched CD34+ cells are mobilized into peripheral blood during stress related to ischemic stroke or acute myocardial infarction. Eur. J. Hematol. 2005, 75, 461-467.  PMID: 16313257
138.   Ratajczak MZ. Cancer Stem Cells – Normal Stem Cells “Jedi” that went over to the “dark side”. Folia Histochem. & Cytobiol. 2005, 43, 175-181.  PMID: 16382880
139.    Ratajczak MZ. RGS16 “tightens the reins” on CXCR4. Blood 2005, 106: 2928-2929.
140.  Honczarenko M, Ratajczak MZ, Nicholson-Weller A, Silberstein LE. Complement C3a Enhances   CXCL12 (SDF-1)-Mediated Chemotaxis of Bone Marrow Hematopoietic Cells Independently of C3a Receptor. J Immunol 2005, 175, 3698-3706.  PMID: 16148115
141.   Cramer DE, Allendorf D, Baran JT, Hansen R, Marroquin J, Li B, Ratajczak J, Ratajczak MZ,  Yan J. Beta-Glucan Enhances Complement-Mediated Hematopoietic Recovery after Bone Marrow Injury. Blood 2006, 107, 835-840.  PMID: 16179370
142.   Kucia M, Zhang PY, Reca R, Wysoczynski M, Machalinski B, Ildstad ST, Ratajczak J, Shields CB,  Ratajczak MZ. Cells enriched in markers or neural tissue-committed stem cells (TCSC) reside in the bone marrow and are mobilized into the peripheral blood following stroke. Leukemia 2006, 20, 18-28.  PMID: 16270036
143.  Wojakowski W, Tendera M, Zebzda A, Michalowska A, Majka M, Kucia M, Maslankiewicz K, Wyderka R, Krol M, Ochala A, Kozakiewicz K, Ratajczak M.Z. Mobilization of CD34+, CD117+, CXCR4+, c-met+ stem cells is correlated with left ventricular ejection fraction and plasma NT-proBNP levels in patients with acute myocardial infarction. Eur. Heart J. 2006, 27:283-289.  PMID: 16267071
144.   Baj-Krzyworzeka M, Szatanek R, Weglarczyk K, Baran J, Urbanowicz B, Branski P, Ratajczak MZ, Zembala M.  Tumour-derived microvesicles carry several surface determinants and mRNA of tumour cells and transfer some of these determinants to monocytes. Cancer Immunol Immunother. 2006, 55: 808-818.  PMID: 16283305
145.   Huang Y, Kucia M, Rezzoug F, Ratajczak J, Tanner MK, Ratajczak MZ, Schanie CL, Xu H, Fugier Vivier I, Ildstad ST. FL-mobilized peripheral blood but not FL-expanded bone marrow FC promote establishment of chimerism and tolerance. Stem Cells  2006, 4, 936-948.  PMID: 16644924
146.   Ratajczak MZ, Reca R, Wysoczynski M, Yan J, Ratajczak J. Modulation of the SDF-1-CXCR4 axis by the third complement component (C3) – Implications for trafficking of CXCR4+ stem cells. Exp. Hematol 2006, 34: 986-995.  PMID: 16863905
147.  Kucia M, Wojakowski W, Reca R, Machalinski B, Gozdzik J, Majka M, Baran J, Ratajczak J, Ratajczak MZ. The migration of bone marrow-derived non-hematopoietic tissue committed stem cells (TCSC) is regulated in SDF-1, HGF and LIF-dependent manner. Arch Immunol. Therap. Exp 2006, 54, 121-135.  PMID: 16648972
148.  Ratajczak J, Miekus K, Kucia M, Zhang J, Reca R, Dvorak P, Ratajczak MZ. Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery. Leukemia 2006, 20:847-856.  PMID: 16453000
149.  Li Y, Reca R, Sonmez P, Ratajczak MZ, Ildstad ST, Kaplan HJ, Enzmann V. Retinal pigment epithelium damage enhances expression of chemoattractants and migration of bone marrow-derived stem cells. Invest Ophthalmol Vis Sci. 2006, 47:1646-1652.  PMID: 16565405
150.    Kucia M, Reca R, Campbell FR, Majka M, Ratajczak J and Ratajczak MZ. A population of very small embryonic like (VSEL) CXCR4+ SSEA-1+ Oct-4+ stem cells identified in adult bone marrow. Leukemia 2006, 20:857-869.  PMID: 16498386
151.  Ratajczak MZ, Kucia M, Dobrowolska H, Wanzeck J, Reca R, Ratajczak J. Emerging concept of cancer as a stem cell disorder. Centr. Eur. J. Biol 2006, 1:73-87.
152.  Wojakowski W, Ratajczak MZ, Tendera M. Interleukin-8: More on mechanisms of progenitor cells mobilization in acute coronary syndromes. Eur Heart J. 2006, 27;1013-1015.  PMID: 16595523
153.  Kucia M, Zuba-Surma E, Wysoczynski M, Dobrowolska H, Reca R, Ratajczak J, Ratajczak MZ. Physiological and pathologcial consequences of identification of very samll embryonic like (VSEL) stem cells in adult bone marrow. J Phys. Pharm. 2006, 57; Suppl 5, 5-18.  PMID: 17218757
154.   Kucia M, Ratajczak MZ. Stem cells as a two edged sword – from regeneration to tumor formation. J. Phys. Pharm. 2006, 57; Suppl 7, 5-16.  PMID: 17228093
155.   Machalinski B, Paczkowska E, Koziarska D, Ratajczak MZ. Mobilization of human hematopoietic   stem/progenitor-enriched CD34+ cells into peripheral blood during stress related to ischemic stroke. Folia Histochem & Cytobil. 2006, 44:97-101.  PMID: 16805134
156.  Ratajczak J, Wysoczynski M, Hayek F, Janowska-Wieczorek A, Ratajczak MZ. Membrane-derived microvesicles (MV): important and underappreciated mediators of cell to cell communication. Leukemia 2006, 20:1487-1495.  PMID: 16791265
157.  Janowska-Wieczorek A, Marquez-Curtis L, Wysoczynski M, Ratajczak MZ. Enhancing effect of platelet-derived microvesicles on the invasive potential of breast cancer cells.  Transfusion 2006, 46, 1199-1209.  PMID: 16836568
158.    Ratajczak MZ, Zuba-Surma E, Kucia M, Reca R, Wojakowski W, Ratajczak J. The pleiotropic effects of the SDF-1-CXCR4 axis in organogenesis, regeneration and tumorogenesis. Leukemia 2006, 20:1915-1924.  PMID: 16900209
159.    Zuba-Surma EK, Abdel-Latif A, Case J, Tiwari S, Hunt G, Kucia M, Vincent RJ, Ranjan S, Ratajczak MZ, Srour EF, Bolli R, Dawn B. Sca-1 expression is associated with decreased cardiomyogenic differentiation potential of skeletal muscle-derived adult primitive cells. J Mol Cell Cardiol 2006, 41:650-660.  PMID: 16938308
160.    Ratajczak MZ. Microparticles from “dust to crown”. Blood 2006, 108: 2885-2886.
161.   Majka M, Drukala J, Lesko E, Wysoczynski M, Jenson AB, Ratajczak MZ. SDF-1 alone and in co-operation with HGF regulates biology of human cervical carcinoma cells. Folia Histochem Cytobiol 2006, 44:155-164.  PMID: 16977794
162.   Ratajczak MZ, NM B-Killman. The fever of stem cells has taken possession of us. Leukemia 2006, 20:1747.
163.    Kucia M, Machalinski B, Ratajczak MZ. The developmental deposition of epiblast/primordial germ cells in various organs as a hypothetical explanation of stem cell plasticity. Acta Neurol. Exp. 2006, 66; 331-341.  PMID: 17265694
164.    Reca R, Wysoczynski M, Yan J, Lambris JD, Ratajczak MZ. The role of third complement component (C3) in homing of hematopoietic stem/progenitor cells into bone marrow. Adv Exp Med Biol. 2006, 586, 35-51.  PMID: 16893063
165.  Son BR, Marquez-Curtis LA, Kucia M, Wysoczynski M, Turner AR, Ratajczak J, Ratajczak MZ, Janowska-Wieczorek A. Migration of bone marrow and cord blood mesenchymal stem cells in vitro is regulated by stromal derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases. Stem Cells 2006, 24, 1254-1264.  PMID: 16410389
166.    Kucia M, Halasa M, Wysoczynski M, Baskiewicz-Masiuk M, Moldenhawer S, Zuba-Surma E, Czajka R, Wojakowski W, Machalinski B, Ratajczak MZ. Morphological and molecular characterization of novel population of CXCR4+ SSEA-4+ Oct-4+ very small embryonic-like (VSEL) cells purified from human cord blood – preliminary report. Leukemia 2007, 21:297–303.  PMID: 17136117
167.    Wysoczynski M, Miekus K, Jankowski K, Wanzeck J, Janowska-Wieczorek A, Ratajczak J, Ratajczak MZ. Leukemia Inhibitory Factor: A newly identified metastatic factor in rhabdomyosarcomas. Cancer Res. 2007, 67:2131-2140.  PMID: 17332343
168.  Wysoczynski M, Kucia M, Ratajczak J, Ratajczak MZ.Cleavage fragments of third complement component (C3) enhance SDF-1 mediated platelet production during reactive thrombocytosis. Leukemia 2007, 21, 860-867.  PMID:  17330096
169.   Ratajczak MZ, Machalinski B, Wojakowski W, Kucia M.  A hypothesis for an embryonic origin of pluripotent Oct-4+ stem cells in adult bone marrow and other tissues. Leukemia 2007, 21, 973-982.  PMID: 17344915
170.    Majka M, Kijowski J, Lesko E, Gozdzik J, Zupanska B, Ratajczak MZ. Evidence that platelet-derived microvesicles may transfer platelet-specific immunoreactive antigens to the surface of endothelial cells and CD34+ hematopoietic stem/ progenitor cells – implication for the pathogenesis of immune thrombocytopenias. Folia Histochem. Cytobiol 2007, 45, 27-32.  PMID: 17378242
171.  Wojakowski W, Kucia M, Kazimierski M, Ratajczak MZ, Tendera M. Circulating stem/progenitor cells in stable ischemic heart disease and acute coronary syndromes – relevant raparatory mechanism? Heart 2008, 94, 27-33.  PMID: 17395668
172.   Kucia M, Wu W, Ratajczak MZ.  Bone marrow-derived very small embryonic like stem cells (VSEL) – their developmental origin and biological significance. Develop. Dynamics 2007, 236:3309-3320.  PMID: 17497671
173.    Wojakowski W, Kucia M, Korzeniewski B, Ratajczak MZ, Tendera M. Trafficking of stem/progenitor cells after myocardial injury. EuroIntervention 2007, 2 (Suppl B), B9-B15.
174.   Zuba-Surma EK, Kucia M, Abdel-Latif A, Lillard JW, Ratajczak MZ. The ImageStream System: A Key Step to a New Era in Imaging. Folia Histiochem. & Cytobiol. 2007, 45, 279-90.  PMID: 18165167
175.   Kucia M, Wysoczysnki M, Ratajczak J, Ratajczak MZ. Identification of Very Small Embryonic Like (VSEL) Stem Cells in Bone Marrow. Cell & Tissue Res. 2008, 331, 125-34.  PMID: 17828555
176.   Kucia M, Zuba-Surma E, Wysoczynski M, Wu W, Ratajczak J, Ratajczak MZ. Adult marrow-derived very small embryonic-like stem cells (VSEL SC) and tissue engineering. Exp. Opinion Biol. Ther. 2007, 10, 1499-1514.  PMID: 17916043
177.    Reca R, Cramer D, Yan J, Laughlin MJ, Janowska-Wieczorek A,  Ratajczak J, Ratajczak MZ. A novel role of complement in mobilization; immunodeficient mice are poor G-CSF mobilizers because they lack complement-activating immunoglobulins. Stem Cells 2007, 25, 3093-3100.  PMID: 17717064
178.   Ratajczak MZ, Ewa K. Zuba-Surma, Machalinski B, Kucia M. Bone marrow-derived stem cells – our key to longevity? J Appl Genet. 2007, 48, 307-319.  PMID: 17998587
179.   Wysoczynski M, Ratajczak J, Reca R, Kucia M, Ratajczak MZ. The third complement component as modulator of platelet production. Adv Exp Med Biol. 2007, 598, 226-239.  PMID: 17892215
180.   Zuba-Surma EK, Kucia M, Ratajczak MZ. “Decoding the dot”: The image stream system (ISS) as a novel powerful tool for flow cytoemtric analysis. Cent. Eur. J. Biol 2008, 3, 1-10.
181.   Ratajczak MZ, Zuba-Surma EK, Wysoczysnki M, Wan W, Ratajczak J, Wojakowski W, Kucia M. “Hunt for pluripotent stem cell – regenerative medicine search for almighty cell” J of Autoimmunity  2008, 30,151-162.  PMID: 18243661
182.   Zuba-Surma EK, Kucia M, Abdel-Latif A, Dawan B, Hall B, Singh R, Lillard JW, Ratajczak MZ. Morphological characterization of very small embryonic-like stem cells (VSELs) by ImageStream system analysis. J Cell Mol Med 2008, 12, 292-303.  PMID: 18031297
183.  Rezzoug F, Huang Y, Tanner MK, Wysoczynski M, Shcanie CL, Chilton PM, Ratajczak MZ, FugierVivier IJ, Ildstad ST. TNF-a is critical to facilitate hematopoietic stem cell engraftment and function. J Immunol 2008, 180, 49-57.  PMID: 18097003
184.    Zuba-Surma EK, Kucia M, Dawn B, Guo Y, Ratajczak MZ, Bolli R. Bone marrow-derived pluripotent very small embryonic-like stem cells (VSELs) are mobilized after acute myocardial infarction. J Moll Cell Cardiol 2008, 44, 865-873.  PMID: 18430437
185.   Ratajczak MZ. Microvesicles as immune orchestra conductors. Blood 2008, 111, 4832-4833.  PMID: 18467599
186.  Ratajczak MZ, Zuba-Surma EK, Wojakowski W, Ratajczak J, Kucia M. Bone marrow home of versatile stem cells. Transf Med & Haemother. 2008, 35, 248-259.  PMID: 21547122
187.   Zuba-Surma EK, Wu W, Ratajczak J, M. Kucia & Ratajczak MZ. Very Small Embryonic-Like Stem Cells in adult tissues – potential implications for aging. Mech Ageing & Develop. 2009, 130, 58-66.  PMID: 18377952
188.  Fanning L, Hegerfeldt Y, Tary-Lehmann M, Lesniewski M, Maciejewski J, Weitzel M, Kozik M, Finney M, Lazarus HM, Paul P, Ratajczak MZ, Meyerson H, Laughlin M. Allogeneic transplantation of multiple umbilical cord blood units in adults: role of pre-transplant mixed lymphocyte reaction to predict host vs. graft rejection. Leukemia 2008, 22, 1786-1790.  PMID: 18354493
189.  Cramer DE,  Wagner S, Li B, Liu J, Hansen R, Reca R, Wu W, Zuba-Surma E, Laber D, Ratajczak MZ, Yan J. Mobilization of Hematopoietic Progenitor Cells by Yeast-derived b-Glucan Requires Activation of Matrix Metalloproteinase-9. Stem Cells 2008, 26, 1231-1240.  PMID: 18339771
190.   Ratajczak MZ, Zuba-Surma E, Ratajczak J, Wysoczynski M, Kucia M. Very Small Embryonic Like (VSEL) Stem Cells – Characterization, Developmental Origin and Biological Significance. Exp Hematol. 2008, 36, 742-751.  PMID: 18474305
191.    Shirvaikar N, Reca R, Jalili A, Marquez-Curtis L,  Fong Lee S,  Ratajczak MZ, Janowska-Wieczorek A. CFU-megakaryocytic progenitors expanded ex vivo from cord blood maintain their in vitro homing potential and express matrix metalloproteinases. Cytotherapy 2008, 10, 182-192.  PMID: 18368597
192.  Ratajczak MZ. Phenotypic and functional characterization of hematopoietic stem cells. Current Opinion Hematol 2008, 15, 293-300.  PMID: 18536565
193.   Ratajczak MZ, Zuba-Surma EK, Machalinski B, Ratajczak J, Kucia M. Very small embryonic-like (VSEL) stem cells: purification from adult organs, characterization, and biological significance. Stem Cell Rev. 2008, 4, 89-99.  PMID: 18459073
194.   Huang Y, Ratajczak MZ, Reca R, Xu H, Tanner M, Rezzoug F, Hussain LR, Fugier-Vivier I, Bolli R, Ildstad ST. Fms-Related Tyrosine Kinase 3 Expression Discriminates Hematopoietic Stem Cells Subpopulations With Differing Engraftment-Potential: Identifying the Most Potent Combination. Transplantation. 2008, 85, 1175-1184.  PMID: 18431239
195.   Dawn B, Tiwari S, Kucia MJ, Zuba-Surma EK, Guo Y, Sanganalmath SK, Abdel-Latif A, Hunt G, Vincent RJ, Taher H, Reed NJ, Ratajczak MZ, Bolli R. Transplantation of Bone Marrow-Derived Very Small Embryonic-like Stem Cells (Vsels) Attenuates Left Ventricular Dysfunction and Remodeling after Myocardial Infarction. Stem Cells 2008, 26, 1646–1655.  PMID: 18420834
196.    Kucia M, Wysoczynski M, Wan W, Zuba-Surma EK, Ratajczak J, Ratajczak MZ. Evidence that very small embryonic like (VSEL) stem cells are mobilized into peripheral blood. Stem Cells 2008, 26, 2083–2092.  PMID: 18511604
197.   Ratajczak MZ, Zuba-Surma EK, Shin DM, Ratajczak J, Kucia M. Very small embryonic-like (VSEL) stem cells in adult organs and their potential role in rejuvenation of tissues and longevity. Exp. Gerontol. 2008, 43, 1009-1017.  PMID: 18601995
198.   Lesniewski ML, Haviernik P, Wietzel RP, Kadereit S, Kozik MM, Fanning LR, Yang YC, Hegerfeldt Y, Finney MR, Ratajczak MZ, Greco N, Paul P, Maciejewski J, Laughlin MJ. Regulation of IL-2 Expression by Transcription Factor BACH2 in Umbilical Cord Blood CD4+ T-cells. Leukemia 2008, 22, 2201–2207.  PMID: 18769450
199.   Wojakowski W, Tendera M, Kucia M, Zuba-Surma E, Paczkowska E, Ciosek J, Hałasa M, Król M, Kaźmierski M, Ochała A, Ratajczak J, Machaliński B, Ratajczak MZ. Mobilization of Bone Marrow-Derived Oct-4+SSEA-4+ Very Small Embryonic-Like Stem Cells in Patients with Acute Myocardial Infarction. J Am Coll Cardiol. 2009, 53, 1-9.  PMID: 19118716
200Paczkowska E, Kucia M, Koziarska D, Hałasa M, Safranow K, Masiuk M, Karbicka A, Nowik M, Nowacki P, Ratajczak MZ, Machalinski B. Clinical evidence that very small embryonic-like (VSEL) stem cells are mobilized into peripheral blood in patients after stroke. Stroke 2009, 40, 1237-1244.  PMID: 19246697
201.    Zuba-Surma EK, Kucia M, Ratajczak J, Ratajczak MZ. “Small stem cells” in adult tissues: Very Small Embryonic-like Stem Cells (VSELs) stand up! Cytometry 2009, 75A, 4-13.  PMID: 18988270
202.  Wojakowski W, Kucia M, Machalinski B, Halasa M, Buszman P, Klimeczek P, Kazmierski M, Pasowicz M, Ratajczak MZ, Tendera M. The role of CXCR4/SDF-1, CD117/SCF, and c-met/HGF chemokine signalling in the mobilization of progenitor cells and the parameters of the left ventricular function, remodelling, and myocardial perfusion following acute myocardial infarction. Eur Heart J 2008, 10, K16-K23.
203.   Ratajczak MZ, Kucia M, Ratajczak J, Zuba-Surma EK. A multi-instrumental approach to identify and purify Very Small Embryonic Like Stem Cells (VSELs) from adult tissues. Micron 2009, 40, 386-393.  PMID: 19028104
204.  Zuba-Surma EK, Wan W, Kucia M, Klich I, Lillards JW, Ratajczak J, Ratajczak MZ. Very Small Embryonic- Like stem cells (VSELs) are present in adult murine organs: ImageStream based morphological analysis and distribution studies. Cytometry 2008, 73A, 1116-1127.  PMID: 18951465
205. Fan T, Kucia M, Jankowski K, Higashi RM, Ratajczak J, Ratajczak MZ, Lane AN.  Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes. Mol Cancer 2008, 7, 79-89.  PMID: 18939998
206.    Ratajczak MZ, Kucia M, Dong-Myung S, Liu R, Drukala J, Marlicz W, Ratajczak J, EK Zuba-Surma. A unique population of mobile very small embryonic/epiblast like (VSEL) stem cells resides in adult tissues: physiological and pathological consequences. J. Cell Ther & Transpl. 2008, 1, 2, 36-43
207.    Ratajczak MZ. Megakaryocyte-derived microvesicles, please stand up! Blood 2009, 113, 981-982.
PMID: 19179472
208.  Drukala J, Majka M, Kwarciak A, Puchala J, Ratajczak MZ. Subpopulation of Rh123dim human keratinocytes is highly enriched for holoclone froming cells. Centr Eur J Biol 2009, 4, 154-162.
209.   Zuba-Surma EK, Kucia M, Liu R, Wojakowski W, Ratajczak J, Ratajczak MZ. Fetal liver very small embryonic like stem cells (VSELs) follow developmental migratory pathway of hematopoietic stem cells. Ann New York Acad. Sci 2009, 1176, 205-218.  PMID: 19796249
210.   Ratajczak MZ, Wysoczynski M, Reca R, Wan W, Zuba-Surma EK, Kucia M, Ratajczak J. A pivotal role of complement cascade (CC) in mobilization of hematopoietic stem/progenitro cells (HSPC). Adv. Exp. Med. Biol. 2008, 632, 47-60.  PMID: 19025113
211.   Tendera M, Wojakowski W, Ruzyllo W, Chojnowska L, Kepka C, Tracz W, Musialek P, Piwowarska W, Nessler J, Buszman P, Grajek S, Breborowicz P, Majka M, Ratajczak MZ. Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: results of randomized, multicentre Myocardial Regeneration by Intracoronary Infusion of Selected Population of Stem Cells in Acute Myocardial Infarction (REGENT) Trial. Eur Heart J 2009, 11, 1313-21.  PMID: 19208649
212.  Ratajczak MZ, Dong-Myung Shin, Kucia M. Very small embryonic-like stem cells (VSELs): a missing link to support the germ line hypothesis of cancer development? Am J Pathol 2009, 174, 1985–1992.  PMID: 19406990
213.   Wysoczynski M, Reca R, Lee H, Wu W, Ratajczak J, Ratajczak MZ. Defective engraftment of C3aR-/- hematopoietic stem cells reveals a novel role of the C3a-C3aR axis in bone marrow homing. Leukemia 2009, 23, 1455-61.  PMID: 19357704
214.    Lee H, Ratajczak MZ. Innate immunity: a key player in mobilization of hematopoietic stem/progenitor cells. Arch. Immunol. Therapie Experiment. 2009, 57, 269-78.  PMID: 19578812
215.   Maksym RB, Tarnowski M, Grymula K, Tarnowska J, Wysoczynski M, Liu R, Czerny B, Ratajczak J, Kucia M, Ratajczak MZ. The role of stromal derived factor-CXCR7 axis in development and cancer. Eur. J Pharmacol. 2009, 625, 31-40.  PMID: 19835865
216.   Wysoczynski M, Ratajczak MZ. Lung cancer secreted microvesicles: underappreciated modulators of microenvironment in expanding tumors. Int. J. Cancer 2009, 125, 1595-1603.  PMID: 19462451
217.    Liu Y, Clem B, Zuba-Surma E, El-Naggar S, Telang S, Jenson AB, Wang Y, Shao H, Ratajczak MZ, Chesney J, Dean DC. Mouse fibroblasts lacking RB1 function form spheres and undergo reprogramming to a cancer stem cell phenotype. Cell Stem Cell 2009, 4, 336-347.  PMID: 19341623
218.   Liu R, Klich I, Ratajczak J, Ratajczak MZ, Zuba-Surma EK. Erythrocyte-derived microvesicles may transfer phosphatidylserine to the surface of nucleated cells and falsely “mark” them as apoptotic. Eur. J Haematol 2009, 174, 1985-1992.  PMID: 19456851
219.  Shin DM, Zuba-Surma EK, Wu W, Ratajczak J, Wysoczynski M, Ratajczak MZ, Kucia M. Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct-4+ very small embryonic like stem cells. Leukemia 2009, 23, 2042-2051.  PMID: 19641521
220.   Liu Y, Gao L, Zuba-Surma EK, Peng X, Kucia M, Ratajczak MZ, Wang W, Enzman V, Kaplan HJ, Dean DC. Identification of small Sca1(+), Lin(-), CD45(-) multipotential cell in the neonatal murine retina. Exp. Hematol 2009, 37, 1096–1107.  PMID: 19539690
221.  Wysoczynski M, Shin DM, Kucia M, Ratajczak MZ. Selective up-regulation of interleukin-8 by human rhabdomyosarcomas in response to hypoxia: therapeutic implications. Int. J. Cancer 2010, 126, 371-381.  PMID: 19588509
222.  Lee H,  Wan W, Wysoczynski M, Liu R, Zuba-Surma EK, Kucia M, Ratajczak J, Ratajczak MZ. Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel effects of granulocytes. Leukemia 2009, 23, 2052-2062.  PMID: 19657368
223.  Zuba-SDurma EK, Klich I, Greco N, Laughlin MJ, Ratajczak J, Ratajczak MZ. Optimization of Isolation and Further Characterization of Umbilical Cord Blood-derived Very Small Embryonic/Epiblast-Like Stem Cells (VSELs). Eur. J Haematol 2010, 84, 34-46.  PMID: 19758351
224.  Zuba-Surma EK, Ratajczak MZ. Overview of Very Small Embryonic-Like Stem Cells (VSELs) and Methodology of Their Identification and Isolation by Flow Cytometric Methods. Current Protocols in Cytometry 2010, Chapter 9:Unit 9.29.  PMID: 20069527
225.   Ratajczak MZ, Shin DM. Why some cells are more equal than others? Blood 2009, 114, 4913-4914.  PMID: 19965701
226.    Lee H, Wysoczynski M, Liu R, Shin DM, Kucia M, Botto M, Ratajczak J, Ratajczak MZ. Mobilization studies in complement-deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes. Leukemia 2010, 24, 573-582.  PMID: 20033053
227.   Shin DM, Kucia M, Ratajczak MZ. Nuclear and chromatin reorganization during cell senescence and aging. Gerontology  2011, 57, 76-84.  PMID: 20134149
228.   Tarnowski M, Grymula K, Reca R, Jankowski K, Maksym R, Tarnowska J, Przybylski G, Barr FG, Kucia M, Ratajczak MZ, Regulation of expression of stromal-derived factor-1 (SDF-1) receptors: CXCR4 and CXCR7 in human rhabdomyosarcomas. Mol. Cancer Res. 2010, 8, 1-14.  PMID: 20068066
229.  Huang Y, Kucia M, Hussain LR, Wen Y, Xu H, Yan J, Ratajczak MZ, Ildstad ST. Bone Marrow Transplantation Temporarily Improves Pancreatic Function in Streptozotocin-Induced Diabetes: Potential Involvement of Very Small Embryonic-Like Cells. Transplantation 2010, 89, 677-685.  PMID: 20110858
230.  Grymula K, Tarnowski M, Wysoczynski M, Drukala J, Barr FG, Ratajczak J, Kucia M, Ratajczak MZ. Overlapping and Distinct Role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 Axes in Regulating Metastatic Behavior of Human Rhabdomyosarcomas. Int J Cancer 2010, 127, 2554–2568.  PMID: 20162608
231.   Ratajczak MZ, Machalinski B, Czajka R, Zuba-Surma E, Poziomkowska-Gesicka  I, Slowik-Zylka D. Physiological and pathological consequences of a presece of germ line stem cells in adult tissues. Ginekol. Pol. 2009, 80, 935-941.  PMID: 20120940
232.    Ratajczak MZ, Shin DM, Liu R, Tarnowski M, Ratajczak J, Kucia M. Epiblast/Germ Line Hypothesis of Cancer Development Revisited: Lesson from the Presence of Oct-4+ Cells in Adult Tissues. Stem Cell Rev & Rep. 2010, 6, 307-316.  PMID: 20309650
233.  Jalili A, Shirvaikar N, Marquez-Curtis N, Qiu Y, Korol Ch, Lee H, Turner AR, Ratajczak MZ, Janowska-Wiecozrek A.  Fifth complement cascade protein (C5) cleavage fragments disrupt the SDF-1/CXCR4 axis: Further evidence that innate immunity orchestrates the mobilization of hematopoietic stem/progenitor cells. Exp Hematol 2010, 38, 321-332.  PMID: 20153802
234.    Ratajczak MZ, Lee HK, Wysoczynski M, Wan W, Marlicz W, Laughlin MJ, Kucia M, Janowska-Wieczorek A, Ratajczak J. Novel insight into stem cell mobilization – Plasma Sphigosine 1 – phosphate is a major chemoattractant that directs egress of hematopoietic stem progenitor cells from bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex.  Leukemia 2010, 24, 976-985.  PMID: 20357827
235.  Ratajczak MZ, Tarnowski M, Staniszewska M, Sroczynski T, Banach B. Mechanisms of cancer metastasis: involvement of cancer stem cells? Miverva Med. 2010, 101, 179-191.  PMID: 20562805
236.   Wysoczynski M, Rui L, Kucia M, Drukala J, Ratajczak MZ. Thrombin regulates metastatic potential of human rhabdomyosarcoma cells – distinct role of PAR1 and PAR3 signaling. Mol. Cancer Res 2010, 8, 677-690.  PMID: 20442298
237.  Wojakowski W. Tendera M, Kucia M, Zuba-Surma E, Milewski K, Wallace-Bradley D, Kazimierski M, Buszman P, Hrycek E, Cybulski W, Kaluza G, Ratajczak J, Ratajczak MZ. Cardiomyocyte differentiation of bone marrow-derived Oct-4+CXCR4+SSEA-1+ very small embryonic-like stem cells. Int J Oncol 2010, 37, 237-247.  PMID: 20596650
238.   Jalili A, Marquez-Curtis L, Shirvaikar N, Wysoczynski M, Ratajczak MZ, Janowska-Wieczorek A. Complement C1q enhances homing-related responses of hematopoietic stem/progenitor cells. Transfusion 2010, 50, 2002-2010.  PMID: 20456695
239.   Shin DM, Liu R, Klich I, Wu W, Ratajczak J, Kucia M, Ratajczak MZ. Molecular signature of adult       bone marrow-purified very small embryonic-like stem cells supports their developmental epiblast/germ line origin. Leukemia 2010, 24, 1450–1461.  PMID: 20508611
240.    Delaney C, Ratajczak MZ, Laughlin MJ. Strategies to enhance UCB stem cell engraftment in adult patients. Exp. Rev. Hemato. 2010, 3, 273-283.  PMID: 20835351
241.    Shin DM, Liu R, Klich I, Ratajczak J, Kucia M, Ratajczak MZ. Molecular characterization of isolated from adult tissues very small embryonic/epiblast like stem cells. Molecules & Cells 2010, 29, 533-538.  PMID: 20526817
242.   Zuba-Surma EK, Guo Y, Taher H, Sanganalmath Sk, Hunt G, Vincent RJ, Kucia M, Abdel-Latif A, Tang XL, Ratajczak MZ, Dawn B, Bolli R. Transplantation of expanded bone marrow-derived very small embryonic-like stem cells (VSEL-SCs) improves left ventricular function and remodeling after myocardial infarction. J Cell Mol Med 2011, 15, 1319-1328.  PMID: 20629987
243.  Ratajczak MZ, Kim CW, Wojakowski W, Janowska-Wieczorek A, Kucia M, Ratajczak J. Innate Immunity as Orchestrator of Stem Cell Mobilization. Leukemia 2010, 24, 1667-75.  PMID: 20703253
244.   Abdel-Latif A , Zuba-Surma EK,  Ziada KM, Kucia M, Cohen DA, Kaplan AM, Van Zant G, Selim S, Smyth SS, Ratajczak MZ. Evidence of Mobilization of Pluripotent Stem Cells into Peripheral Blood of Patients with Myocardial Ischemia. Exp Hematol 2010, 38, 1131-1142.  PMID: 20800644
245.   Ratajczak MZ. Spotlight Series on Stem Cell Mobilization: Many Hands on the Ball, but who is the Quarterback? Leukemia 2010, 24, 1665-1656.  PMID: 20940722
246.   Tarnowski M, Grymula K, Liu R, Tarnowska J, Drukala J, Ratajczak J, Mitchell RA, Ratajczak MZ, Kucia M. Macrophage Migration Inhibitory Factor is secreted by rhabdomyosarcoma cells, modulates tumor metastasis by binding to CXCR4 and CXCR7 receptors and inhibits recruitment of Cancer Associated Fibroblasts.. Mol. Cancer Res. 2010, 8, 1328–1343.  PMID: 20861157
247.   Tarnowski M, Liu R, Wysoczynski M, Ratajczak J, Kucia M, Ratajczak MZ. CXCR7; A new SDF-1 binding receptor in contrast to nomal CD34+ progenitors is functional and is expressed at higher level in human malignant hematopoietic cells. Eur J Haematol. 2010, 85, 472-483.  PMID: 20887389
248.  Taichman RS, Wang Z, Shiozawa Y, Jung J, Song J, Balduino A, Wang J, Patel LR, Havens AM, Kucia M, Ratajczak MZ, Krebsbach PH. Prospective identification and skeletal localization of cells capable of multilineage differentiation in vivo. Stem Cells Dev 2010, 19, 1557-1570.  PMID: 20446812
249.  Ratajczak J, Wysoczynski M, Zuba-Surma E, Wan W, Kucia M, Yoder MC, Ratajczak MZ. Adult murine bone marrow-derived very small embryonic-like stem cells (VSELs) differentiate into the hematopoietic lineage after co-culture over OP9 stromal cells.  Exp. Hematol. 2011, 39, 225-237.  PMID: 21034791
250.    Wojakowski W, Kucia M, Zuba-Surma E, Jadczyk T, Ksiazek B, Ratajczak MZ, Tendera M. Very small embryonic-like stem cells in cardiovascular repair. Pharmacol Ther 2011, 129, 21–28.  PMID: 20971132
251.    Wojakowski W, Ratajczak MZ, Tendera M. Mobilization of very small embryonic-like stem cells in acute coronary syndromes and stroke. Herz 2010, 35, 467–473.  PMID: 20981396
252.  Ratajczak MZ, Shin DM, Ratajczak J, Kucia M, Bartke A. A novel insight into aging: are there      pluripotent very small embryonic-like stem cells (VSELs) in adult tissues overtime depleted in an Igf-1-dependent manner? Aging 2010, 2, 875-883.  PMID: 21084728
253.  Ratajczak MZ, Liu R, Ratajczak J, Kucia M, Shin DM. The Role of Pluripotent Embryonic-like Stem Cells Residing in Adult Tissues in Regeneration and Longevity. Differentiation 2011, 81, 153-161.  PMID: 21339038
254. Ratajczak J, Shin DM, Wan W, Liu R, Masternak M, Piotrowska K, Wiszniewska B, Kucia M, Bartke A, Ratajczak MZ. Higher number of stem cells in bone marrow of circulating Igf-1 level low Laron dwarf mice – novel view on Igf-1, stem cells and aging. Leukemia 2011, 25, 729–733.  PMID: 21233833
255. Wojakowski W, Kucia M, Liu R, Zuba-Surma E, Jadczyk T, Bachowski R, Nabialek E, Kazmierski M, Ratajczak MZ, Tendera M. Circulating Very Small Embryonic-Like Stem Cells in Cardiovascular Disease. J. Cardiovasc Transl Res. 2011, 4,138-44.  PMID: 21165781
256. Zuba-Surma EK, Wojakowski W, Ratajczak MZ, Dawn B. Very small embryonic-like stem cells: Biology and therapeutic potential for heart repair. Antioxidants & Redox Signaling 2011, 15, 1821-1834.  PMID: 21194389
257.  Ratajczak MZ, Kim CH, Wan W, Shin DM, Kucia M, Ratajczak J. The Role of Innate Immunity in Trafficking of Hematopoietic Stem Cells – An Emerging Link between Activation of Complement Cascade and Chemotactic Gradients of Bioactive Sphingolipids.  Adv Exp Med Biol. 2012, 946, 37-54.  PMID: 21948361
258. Ratajczak J, Zuba-Surma E, Paczkowska E, Kucia M, Nowacki P, Ratajczak MZ. Stem cells for neural regeneration – a potential application of Very Small Embryonic-Like Stem Cells (VSELs). J Physiol Pharmacol. 2011, 62, 3-12.  PMID: 21451204
259.  Ratajczak MZ. The Emerging Role of Microvesicles in Cellular Therapies for Organ/Tissue Regeneration. Nephrology Dial. Transpl. 2011, 26, 1453-1456.  PMID: 21531733
260. Ratajczak MZ, ChiHwa K.  Bioactive Sphingolipids and Complement Cascade as new emerging regulators of stem cell mobilization and homing. J Stem Cell Res & Ther. 2011, 1, 2, 1000e102.
261. Ratajczak J, Zuba-Surma E, Klich I, Liu R, Wysoczynski M, Greco N, Kucia M, Laughlin MJ, Ratajczak MZ. Hematopoietic differentiation of umbilical cord blood-derived very small embryonic/epiblast-like stem cells. Leukemia 2011, 25, 1278–1285.  PMID: 21483440
262.  Ratajczak MZ. Alan M. Gewirtz, 1949–2010: Per aspera ad astra. Stem Cells 2011, 29, 743.
263.  Kucia M, Shin DM, Liu R, Ratajczak J, Bryndza E, Masternak MM, Bartke A, Ratajczak MZ. Reduced number of VSELs in bone marrow of Growth Hormone transgenic mice indicate that chronically elevated Igf-1 level accelerates age-dependent exhaustion of pluripotent stem cell pool – novel view on aging. Leukemia 2011, 25, 1370-1374.  PMID: 21566652
264. Drukała J, Paczkowska E, Kucia M, Młyńska E, Krajewski A, Machaliński B, Madeja Z, Ratajczak MZ. Stem cells, including a population of Very Small Embryonic-Like Stem Cells, are mobilized into peripheral blood in patients after skin burn injury. Stem Cell Rev 2012, 8, 184-194.  PMID: 21573962
265. Kim CH, Wu W, Wysoczynski M, Abdel-Latif  A,  Sunkara M, Morris A,  Kucia M, Ratajczak J, Ratajczak MZ. Conditioning for hematopoietic transplantation activates the complement cascade and induces a proteolytic environment in bone marrow – a novel role for bioactive lipids and soluble C5b-C9 as homing factors. Leukemia 2012, 26, 106–116.  PMID: 21769103
266. Ratajczak MZ, Liu R, Marlicz W, Blogowski W, Starzynska T, Wojakowski W, Zuba-Surma E. Identification of Very Small Embryonic/Epiblast-Like Stem Cells (VSELs) Circulating in Peripheral Blood During Organ/Tissue Injuries. Methods Cell Biol. 2011, 103C, 31-54.  PMID: 21722799
267. Zuba-Surma EK, Ratajczak MZ. Analystical Capabilites of the ImageStream Cytometer. Methods Cell Biol. 2011, 102, 207-230.  PMID: 21704840
268. Ratajczak MZ. New Stem Cell Meeting on the Baltic Sea is Launched. Leukemia 2012, 26, 164-166.  PMID: 21769102
269. Marquez-Curtis LA, Turner AR, Sridharan S, Ratajczak MZ, Janowska-Wieczorek A. The Ins and Outs of Hematopoietic Stem Cells: Studies to Improve Transplantation Outcomes. Stem Cell Rev. 2011, 7, 590-607.  PMID: 21140298
270. Ratajczak MZ, Kucia M, Liu R, Shin DM, Bryndza E, Masternak MM,  Tarnowski M, Ratajczak J, Bartke A. RasGrf1: genomic imprinting, VSELs, and aging. Aging 2011, 3, 692-697.  PMID: 21765200
271.  Ratajczak MZ, Kim CH, Abdel-Latif A, Schneider G, Kucia M, Morris AJ, Laughlin ML, Ratajczak J. A novel perspective on stem cell homing and mobilization – review on bioactive lipids as potent chemoattractants and cationic peptides as underappreciated modulators of responsiveness to SDF-1 gradients. Leukemia 2012, 26, 63–72.  PMID: 21886175
272. Wu W, Kim CH, Liu R, Kucia M, Marlicz W, Greoc N, Ratajczak J, Laughlin ML, Ratajczak MZ. Bone marrow expressed antimicrobial cationic peptide LL-37 enhances responsiveness of hematopoietic stem progenitor cells to an SDF-1 gradient and accelerates their engraftment after transplantation. Leukemia 2012 Apr; 26(4):736-45.  PMID: 21931324
273. Chow R, Lin A, Tonai R, Bolanos R, Connor C, Mendoza A, Heminger R, Chow M, Ho E, Kang J, Gindy L, Fu C, Rao A, Gau JF, Wang BC, Klich I, Ratajczak J, Ratajczak M, Petz LD. Cell recovery comparison between plasma depletion/reduction- and red cell reduction-processing of umbilical cord blood. Cytotherapy 2011, 13, 1105-1119.  PMID: 21867465
274. Shin DM, Liu R, Wu W, Waigel SJ, Zacharias W, Ratajczak MZ, Kucia M. Global gene expression analysis of very small embryonic-like stem cells reveals that the Ezh2-dependent bivalent domain mechanism contributes to their pluripotent state. Stem Cells & Develop. 2012 Jul 1; 21(10):1639-52.  PMID: 22023227
275. Zuba-Surma EK, Wojakowski W, Madeja Z, Ratajczak MZ. Stem Cells as a Novel Tool for Drug Screening and Treatment of Degenerative Diseases. Current Pharm Design 2012;18(18):2644-56.  PMID: 22512442
276.  Marlicz W, Zuba-Surma E, Kucia M, Blogowski W, Starzynska T,  Ratajczak MZ. Various Types of Stem Cells, Including a Population of Very Small Embryonic-Like Stem Cells (VSELs), are Mobilized into Peripheral Blood in Patients with Crohn’s Disease (CD). Inflammatory Bowel Diseases 2012 Sep; 18(9):1711-22.  PMID: 22238186
277. Ratajczak MZ, Kucia M, Jadczyk T, Greco NJ, Wojakowski W, Tendrea M, Ratajczak J. Pivotal Role of Paracrine Effects in Stem Cell Therapies in Regenerative Medicine – Can We Translate Stem Cell-Secreted Paracrine Factors and Microvesicles into Better Therapeutic Strategies? Leukemia 2012 Jun; 26(6):1166-73.  PMID: 22182853
278. Kucia M, Masternak M, Liu R, Shin DM, Ratajczak J, Mierzejewska K, Spong A, Kopchick JJ< Bartke A, Ratajczak MZ. The negative effect of prolonged somatotrophic/insulin signaling on an adult bone marrow-residing population of pluripotent very small embryonic-like stem cells (VSELs). Age 2013 Apr; 35(2):315-30.  PMID: 22218782
279. Wyderka R, Wojakowski W, Jadczyk T, Maslankiewicz K, Parma Z, Pawlowski T, Musialek P, Majka M, Król M, Kuczmik W, Dworowy S, Korzeniowska B, Ratajczak MZ, Tendera M. Mobilization of CD34+CXCR4+ stem/progenitor cells and the parameters of left ventricular function and remodeling in 1 year follow up of patients with acute myocardial infarction. Med. Inflamm 2012; 2012:564027.  PMID: 22547906
280. Ratajczak MZ, Kim CH. The use of chemokine receptor agonists in stem cell mobilization. Exp Opinion Biol Ther. 2012 Mar; 12(3):287-97.  PMID: 22263752
281. Golan K, Vagima Y, Ludin A, Cohen-Gut S, Kalinkovich A, Kollet O, Kim CH, Schajnovitz A, Ovadaya Y, Lapid K, Shivtiel S, Morris AJ, Ratajczak MZ, Lapidot T.  S1P promotes murine progenitor cell egress and mobilization via S1P1 mediated ROS signaling and SDF-1 release. Blood 2012, 119, 2478-2488.  PMID: 22279055
282.  Ratajczak MZ, ChHwa Kim, Ratajczak J, Janowska-Wieczorek A. Innate immunity as orchestrator of bone marrow homing for hematopoietic stem/progenitor cells. Adv Exp Med Biol 2013; 735:219-32.  PMID: 22990706
283.  Janowska-Wieczorek A, Marquez-Curtis LA, Shirvaikar N, Ratajczak MZ. The Role of Complement in the Trafficking of Hematopoietic Stem/Progenitor Cells. Transfusion 2012 Dec; 52(12):2706-16. doi: 10.1111/j.1537-2995.2012.03636.x. Epub 2012 Apr 9.  PMID: 22486360
284. Ratajczak MZ. Igf2-H19, an imprinted tandem gene, is an important regulator of embryonic development, a guardian of proliferation of adult pluripotent stem cells, a regulator of longevity, and a “passkey” to cancerogenesis. Folia Histochem & Cytobiol 2012 Jul 5; 50(2):171-9.  PMID: 22763974
285.  Ratajczak MZ, Suszynska M, Pedziwiatr D, Mierzejwska K, Greco NJ. Umbilical Cord Blood-derived very small embryonic like stem cells (VSELs) as a source of pluripotent stem cells for regenerative medicine. Ped. Endocrin Rev 2011, 9, 546-551.  PMID:22523831
286. Ratajczak J, Kucia M, Mierzejewska  K, Liu R, Kim CH, Natarajan N, Sharma V,  Miller DM, Maciejewski J,  Ratajczak MZ. A novel view of Paroxysmal Nocturnal Hemoglobinuria (PNH) pathogenesis: more motile PNH hematopoietic stem/progenitor cells (HSPCs) displace normal HSPCs from their niches in bone marrow due to defective adhesion, enhanced migration and mobilization in response to erythrocyte-released sphigosine-1 phosphate (S1P) gradient. Leukemia 2012 Jul; 26(7):1722-5. doi: 10.1038/leu.2012.46. Epub 2012 Feb 20.  PMID: 22343521
287.  Ratajczak MZ, Zuba-Surma E, Kucia M, Poniewierska A,  Suszynska M, Ratajczak J. Pluripotent and multipotent stem cells in adult tissues. Adv Med Sci 2012 Jun 1; 57(1):1-17. doi: 10.2478/v10039-012-0020-z.  PMID: 22515973
288. Tarnowski M, Schneider G, Amann G, Clark G, Houghton P, Barr FG, Kenner L, Ratajczak MZ,  Kucia M. RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas. Int J Cancer 2012 Sep;41(3):995-1004.  PMID: 22752028
289. Ratajczak MZ, Kim CH, Janowska-Wieczorek A, Ratajczak J. The expanding family of bone marrow homing factors for hematopoietic stem cells (HSCs) – stromal derived factor-1 (SDF-1) is not the only player in the game. World Sci Journal 2012, Article ID 758512.  PMID: 22701372
290. Ratajczak MZ, Shin DM, Liu R, Mierzejewska K, Ratajczak J, Kucia M,  Zuba-Surma EK. Very small embryonic/epiblast-like stem cells (VSELs) and their potential role in aging and organ rejuvenation – an update and comparison to other primitive small stem cells isolated from adult tissues. Aging 2012, 4, 235-246.  PMID: 22498452
291. Błogowski W, Ratajczak MZ, Zyżniewska-Banaszak E, Dołęgowska B, Starzyńska T. Adipose tissue as a potential source of hematopoietic stem/progenitor cells. Obesity (Silver Spring) 2012, 20, 923-931.  PMID: 22282043
292. Słuczanowska-Głąbowska S, Laszczyńska M, Piotrowska K, Głąbowski W, Kopchick JJ, Bartke A , Kucia M, Ratajczak MZ. Morphology of ovaries in Laron dwarf mice, with low circulating plasma levels of insulin-like growth factor-1 (IGF-1), and in bovine GH-transgenic mice, with high circulating plasma levels of IGF-1. J Ovar Res. 2012, 5:18.  PMID: 22747742
293. Ratajczak MZ, Serwin K, Schneider G. Innate immunity derived factors as external modulators of the CXCL12 – CXCR4 axis and their role in stem cell homing and mobilization. Theranostics 2013, 3, 3-10.  PMID: 23382780
294. Ratajczak MZ, Borkowska S, Ratajczak J. An emerging link in stem cell mobilization between activation of the complement cascade and the chemotactic gradient of sphingosine-1- phosphate. Prostaglandins & Other Lipid Mediators 2013, 104-105, 122– 129.  PMID: 22981511
295. Liu R, Ratajczak MZ. Numeration of very small embryonic-like stem cells in peripheral blood. Methods Mol Biol 2012, 904, 207-219.  PMID: 22890934
296. Ratajczak MZ. Igf2-H19, an imprinted tandem Yin-Yang gene and its emerging role in development, proliferation of pluripotent stem cells, senescence and cancerogenesis. J Stem Cell Res & Ther. 2012, 2:e108.  PMID: 24380039
297. Ratajczak J, Kucia M, Mierzejewska K, Marlicz W, Pietrzkowski Z, Wojakowski W, Greco NJ, Tendera M, Ratajczak MZ. Paracrine pro-angiopoietic effects of human umbilical cord blood-derived purified CD133+ cells – implications for stem cell therapies in regenerative medicine. Stem Cells & Development 2013, 22, 422-430.  PMID: 23003001
298. Ratajczak MZ , Mierzejewska K, Ratajczak J, Kucia M. CD133 expression strongly correlates with the phenotype of very small embryonic/epiblast-like stem cells. Adv. Exp. Med & Biol 2013, 777, 125-141.  PMID: 23161080
299. Ratajczak MZ, Shin DM, Schneider G, Ratajczak J, Kucia M.  Parental imprinting regulates insulin-like growth factor signaling – a Rosetta Stone for understanding the biology of pluripotent stem cells, aging and cancerogenesis. Leukemia 2013, 27, 773–779.  PMID: 23135355
300. Kim CH, Schneider G, Abdel-Latif A, Mierzejewska K, Sunkara M, Borkowska S, Ratajczak J, Morris AJ, Kucia K, Ratajczak MZ. Ceramide-1-phosphate regulates migration of multipotent stromal cells (MSCs) and endothelial progenitor cells (EPCs) – implications for tissue regeneration. Stem Cells 2013, 31, 500-510.  PMID: 23193025
301. Kucharska-Mazur J, Pedziwiatr  D, Poniewierska  A, Tkacz M, Suszynska  M, Tarnowski  M, Samochowiec  J, Ratajczak  MZ. A lack of positive effect of enhanced vegetative nervous system tonus on mobilization of hematopoietic stem and progenitor cells in patients suffering from acute psychotic syndromes. Leukemia 2013, April; 27(4):959-61. doi:10.1038/leu.2012.349. Epub 2012 Dec 4.  PMID: 23207520
302. Karapetyan AV, Klyachkin YM, Selim SM, Sunkara M, Ziada KM, Cohen DA, Zuba-Surma E, Ratajczak J, Smyth SS, Ratajczak MZ, Morris AJ, Abdel-Latif A. Bioactive Lipids and Cationic Antimicrobial Peptides As New Potential Regulators for Trafficking of Bone Marrow Derived Stem Cell In Patients With Acute Myocardial Infarction. Stem Cells Dev. 2013, 22, 1645-1656.  PMID: 23282236
303. Piotrowska K, Borkowska S, Wiszniewska B, Laszczyńska M, Słuczanowska-Głąbowska S, Havens A, Kopchick JJ, Bartke A, Taichman RS, Kucia M,  Ratajczak MZ. The effect of low and high plasma levels of insulin-like growth factor-1 (IGF-1) on the morphology of major organs—studies of Laron dwarf and bovine growth hormone transgenic (bGHTg) mice. Histol Histopathol 2013, 28, 1325-1336.  PMID: 23613169
304. Bartke A, Westbrook R, Sun L, Ratajczak M. Links between growth hormone and aging. Endokrynol Pol. 2013, 64, 46-52.  PMID: 23450447
305. Borkowska S, Suszynska M, Wysoczynski M, Ratajczak MZ. Mobilization studies in C3-deficient mice unravel the involvement of a novel crosstalk between the coagulation and complement cascades in mobilization of hematopoietic stem/progenitor cells (HSPCs). Leukemia 2013 Sep; 27(9):1928-30. doi: 10.1038/leu.2013.84. Epub 2013 Mar 20.  PMID: 23511127
306. Mierzejewska K, Heo J, Kang JW, Kang HS, Ratajczak J, Ratajczak MZ, Kucia M, Shin GM.  Genome-wide analysis of murine bone marrow-derived very small embryonic-like stem cells reveals that mitogenic growth factor signaling pathways play a crucial role in their quiescence and ageing. Int. J. Mol Med. 2013, 32, 281-290.  PMID: 23708325
307. Schneider G, Bryndza E, Abdel-Latif A, Ratajczak J, Maj M, Tarnowski M, Klyachkin Y, Houghton P, Morris AJ, Vater A, Klussmann S, Kucia M, Ratajczak MZ. Bioactive lipids sphingosine-1-phosphate and ceramide-1- phosphate are pro-metastatic factors in human rhabdomyosarcomas cell lines, and their tissue level increases in response to radio/chemotherapy. Mol. Cancer Res. 2013, 11, 793-807.
308. Starzyńska T, Dąbkowski K, Błogowski W, Zuba-Surma E, Budkowska M, Sałata D, Dołęgowska B, Marlicz W, Lubikowski J, Ratajczak MZ. An intensified systemic trafficking of bone marrow-derived stem/progenitor cells in patients with pancreatic cancer. J Cell Mol Med 2013, 17, 792-799.  PMID: 23672538
309. Brunstein CG, McKenna DH, Defor TE, Sumstad D, Paul P, Weisdorf DJ, Ratajczak M, Laughlin MJ, Wagner JE.  Complement fragment 3a priming of umbilical cord blood progenitors: safety profile.
Biol Blood Marrow Transplant. 2013 Oct; 19(10):1474-9. doi: 10.1016/j.bbmt.2013.07.016. Epub 2013 Jul 25.  PMID: 23892047
310. Ratajczak MZ, Zuba-Surma E, Wojakowski W, Suszynska M, Mierzejewska K, Liu R, Ratajczak J, Shin DM,  Kucia M. Very Small Embryonic Like Stem Cells (VSELs) represent a real challenge in stem cell biology. Recent pros and cons in the midst of a lively debate. Leukemia 2014 Mar; 28(3):473-84. doi: 10.1038/leu.2013.255. Epub 2013 Sep 10.  PMID: 24018851
311. Wedrychowicz A, Sztefko K, Majka M, Ratajczak MZ. The role of Insulin-like Growth Factor 1, Receptor Activator for Nuclear Factor κB ligand – Osteoprotegerin system, Interleukin 6 and 1β in post-transplantation bone metabolic disease in childhood. Endokrynol Pol. 2013, 64, 248-54.  PMID: 24002950
312.  Sluczanowska-Glabowska S, Laszczynska M, Piotrowska K, Glabowski W, Rumianowski B, Masternak M, Arum O, Kucia M, Kopchick JJ, Bartke A, Ratajczak MZ. The effect of calorie restriction on the presence of apoptotic ovarian cells in normal wild type mice and low-plasma-IGF-1 Laron dwarf mice. J Ovar Res 2013 Sep 24; 6(1):67. doi: 10.1186/1757-2215-6-67. PMID: 24063422
313. Ratajczak MZ, Suszynska M, Borkowska S, Ratajczak J, Schneider G. The role of sphingosine-1-phosphate (S1P) and ceramide-1-phosphate (C1P) in the trafficking of normal and malignant cells. Exp Opinion Ther Targets 2014 Jan; 18(1):95-107. doi: 10.1517/14728222.2014.851671. Epub 2013 Nov 4.  PMID: 24188167
314. Schneider G, Bowser MJ, Shin DM, Barr FG, Ratajczak MZ. The paternally imprinted DLK1GTL2 locus is differentially methylated in embryonal and alveolar rhabdomyosarcomas. Int J Oncol 2014 Jan; 44(1):295-300. doi: 10.3892/ijo.2013.2153. Epub 2013 Oct 29.  PMID: 24173021
315. Mierzejewska K, Klatchkin Y, Ratajczak J, Kucia M, Abdel-Latif A, Ratajczak MZ.  Sphingosine-1-phosphate-mediated mobilization of hematopoietic stem/progenitor cells during intravascular hemolysis requires attenuation of SDF-1–CXCR4 retention signaling in bone marrow. BioMed Research International 2013; 2013:814549. doi: 10.1155/2013/814549. Epub 2013 Dec 29.  PMID: 24490172
316. Kucharska Mazur J, Tarnowski  M, Dołęgowska B, Budkowska M,  Pędziwiatr D, Jabłoński  M, Pełka Wysiecka J, Kazimierczak A, Ratajczak MZ,  Samochowiec J. Novel evidence for enhanced stem cell trafficking in antipsychotic-naïve subjects during their first psychotic episode. J Psych Research 2013, 2014 Feb; 49:18-24. doi: 10.1016/j.jpsychires.2013.10.016. Epub 2013 Nov 5.  PMID: 24246416
317. Shin DM, Suszynska M, Mierzejewska K, Ratajczak J, Ratajczak MZ. Very small embryonic-like stem-cell optimization of isolation protocols: an update of molecular signatures and a review of current in vivo applications.Exp Mol Med. 2013, 45, e56.  PMID: 24232255
318. Suszynska M, Zuba-Surma EK, Maj M, Mierzejewska K, Ratajczak J, Kucia M, Ratajczak MZ. The proper criteria for identification and sorting of very small embryonic-like stem cells (VSELs), and some nomenclature issues. Stem Cells & Development 2014, 23, 702-713.  PMID: 24299281
319. Ratajczak MZ, Jadczyk T, Schneider G, Kakar SS, Kucia M. Induction of a tumor-metastasis-receptive microenvironment as an unwanted and underestimated side effect of treatment by chemotherapy or radiotherapy. J Ovarian Res. 2013, 6, 95.  PMID: 24373588
320. Beach A, Zhang HG, Ratajczak MZ, Kakar SS. Exosomes: an overview of biogenesis, composition and role in ovarian cancer. J Ovarian Res 2014, 7, 14.  PMID: 24460816
321. Borkowska S, Suszynska M, Mierzejewska K, Ismail A, Budkowska M, Salata D, Dolegowska B, Kucia M, Ratajczak J, Ratajczak MZ. Novel evidence that crosstalk between the complement, coagulation, and fibrinolysis proteolytic cascades is involved in mobilization of hematopoietic stem/progenitor cells (HSPCs). Leukemia 2014, 15 April 2014; doi:10.1038/leu.2014.115.  PMID: 24667943
322. Grymula K, Tarnowski M, Piotrowska K, Suszynska M, Mierzejewska K, Borkowska S, Fiedorowicz K, Kucia M, Ratajczak MZ. Evidence that the population of queiscent bone marrow-residing very small embryonic/epiblast-like stem cells (VSELs) expands in response to neurotixc teratment. J Cell Mol Med 2014, 18, 1797-1806.  PMID: 24895014
323. Ratajczak MZ, Schneider G, Sellers ZP, Kucia M, Kakkar SS. The embryonic rest hypothesis of cancer development – an old XIX century theory revisited. J Cancer Stem Cell Res 2014 (in press).
324. Brodowska A, Brodowski J, Laszczyńska M, Rumianowski B, Słuczanowska-Głąbowska S, Rotter I, Starczewski A, Ratajczak MZ. Immunoexpression of aromatase cytochrome P450 and 17β-hydroxysteroid dehydrogenase in women’s ovaries after menopause. J Ovarian Res 2014, 7, 52.  PMID: 24855493
325. Wysoczynski M, Solanki M, Borkowska SJ, van Hoose P, Brittian KR, Prabhu SD, Ratajczak MZ, Rokosh G. Complement component 3 is necessary to preserve myocardium and myocardial function in chronic myocardial infarction. Stem Cells 2014; 32:2502-2515.  PMID: 24806427
326. Wen Y, Elliott MJ, Huang Y, Miller TO, Corbin DR, Hussain LR, Ratajczak MZ, Fukui Y, Ildstad ST. DOCK2 is critical for CD8+TCR graft facilitating cells to enhance engraftment of hematopoietic stem and progenitor cells. Stem Cells 2014; 32:2732-2743.  PMID: 25044556
327. Suszynska M, Poniewierska-Baran A, Gunjal P, Ratajczak J, Marycz M, Kakkar SS, Kucia M, Ratajczak MZ. Expression of the erythropoietin receptor by germline-derived cells – further support for a potential developmental link between the germline and hematopoiesis. J Ovarian Res 2014, 7, 66.  PMID: 24982693
328. Grymula K, Piotrowska K, Słuczanowska-Głąbowska S, Mierzejewska K, Tarnowski M, Tkacz M, Poniewierska – Baran A, Pędziwiatr D, Suszyńska E, Laszczyńska M,  Ratajczak MZ. Positive effects of prolonged caloric restriction on the population of very small embryonic-like stem cells – hematopoietic and ovarian implications. J Ovarian Res 2014, 7, 68.  PMID: 24987461
329. Ratajczak MZ, Jadczyk T, Pędziwiatr D, Wojakowski W. New advances in stem cell research: practical implications for regenerative medicine. Pol Arch Med Wewn 2014, 124, 417-426.  PMID: 24956404
330. Schneider G, Sellers ZP, Abdel-Latif A, Morris AJ, Ratajczak MZ. Bioactive Lipids, LPC and LPA, are Novel Pro-metastatic Factors and Their Tissue Levels Increase in Response to Radio/Chemotherapy. Mol Cancer Res 2014 Jul 17.  PMID: 25033840
331. Wysoczynski M, Ratajczak J, Pedziwiatr D, Rokosh G, Bolli R, Ratajczak MZ. Identification of heme oxygenase 1 (HO-1) as a novel negative regulator of mobilization of hematopoietic stem/progenitor cells. Stem Cell Rev & Reports 2014 Aug 3 (in press).  PMID: 25086571
332. Ratajczak MZ, Marycz K, Poniewierska-Baran A, Fiedorowicz K, Zbucka-Kretowska M, Moniuszko M. Very small embryonic-like stem cells as a novel developmental concept and the hierarchy of the stem cell compartment. Adv Med Sci. 2014, 59, 273-280.  PMID: 25170822

 

Publications in Polish: (refereed full papers indexed and abstracted in Medline or Excerpta Medica):

1.     Ratajczak M.Z., Ptasznik A.: Application of monoclonal antibodies in clinical medicine (review).  Pol. Tyg. Lek. 1984, 44, 1521 – 1525.
2.     Ratajczak M.Z., Jaskulski D.: In vitro cytostatic assays – clinical implications (review).  Pol. Tyg. Lek. 1984, 39, 1745 – 1749.
3.     Ratajczak M.Z., Jedrzejczak W.W.: Fetal liver as a source of hemopoietic stem cells for potential transplantations (editorial review).  Pol. Tyg. Lek. 1985, 40, 917 – 921.
4.     Jedrzejczak W.,  Rokicka-Milewska R., Siekierzynski M., Szczylik C., Pojda Z., Derulska D.,  Ratajczak M.Z., Klos M., Kansy J., Nowakowska W.:  Autologous bone marrow transplantation as an attempt to maintain complete remission in a child with lymphoblastic leukemia. Ped. Pol. 1986, 61, 177 – 180.
5.     Jedrzejczak W.W., Szczylik C., Pojda Z., Ratajczak M.Z., Siekierzynski M., Kansy J., Klos M., Jaskulski D., Pejcz J., Urbanowska E., Gornas P.:  Practical problems of bone marrow transplantation (review).  Pol. Tyg. Lek. 1988, 48, 923 – 928.
6.     Ratajczak M.Z., Jedrzejczak W.W.: Depletion of erythrocytes from the suspension of bone marrow cells in cases of major ABO incompatibility using polysaccharide – ditrizoate gradient centrifugation. Pol. Tyg. Lek. 1987, 46, 908 – 912.
7.     Ratajczak M.Z., Urbanowska E.: The role of oncogenes in human neoplasia (review). Pol. Tyg. Lek. 1988, 47, 148 – 152.
8.     Szczylik C., Ratajczak M.Z., Siekierzynski M., Kansy J., Klos M., Dumanski Z., Zaborowski P., Matej H., Jedrzejczak W.W.: The rejection of HLA histocompatible bone marrow. A case report.  Pol. Arch. Med. Wew. 1988, 1, 43 – 47.
9.     Ratajczak M.Z., Szczylik C.: Autologous bone marrow transplantation (review). Pol. Tyg. Lek. 1988, 43, 148 – 152.
10. Ratajczak M.Z., Trawicki W., The system of protein kinase C in regulation of cell growth (editorial review).  Pol. Tyg. Lek. 1989, 43, 963 – 970.
11. Jedrzejczak W.W., Ratajczak M.Z.: Depletion of erythrocytes from bone marrow cell suspension using centrifugation over polysacharide – ditrizoate gradient. Description of method. Acta. Haematol. Pol. 1987, 3, 216 – 220.
12. Jedrzejczak W.W., Matej H., Szczylik C., Pojda Z., Ratajczak M.Z.,   Myc  A., Siekierzynski M., Kansy J., Klos M., Rybicki Z., Dumanski Z.,  Zaborowski P., Zaboklicki S., Nowakowska B., Urbanowska E., Nowak J.: Allogeneic HLA histocompatible bone marrow transplants. First results. Pol. Tyg. Lek.  1988, 48, 125 – 129.
13. Ratajczak M.Z., Dudziak M.: Gastroenterological complications of bone marrow transplantation (review). Pol. Tyg. Lek. 1990, 49, 716 – 720.
14. Ratajczak M.Z., Dudziak M.: Renal complications of bone marrow transplantation (review).  Pol. Tyg. Lek. 1990, 50, 836 – 840.
15. Ratajczak M.Z., Issakiewicz R.: Pulmonary complications of bone marrow transplantation (editorial review). Pol. Tyg. Lek. 1991, 50, 399 – 402.
16. Ratajczak M.Z., Szczylik C., Jedrzejczak W.W.: Changes in serum protein concentrations in patients after bone marrow transplantation.  Pol. Tyg. Lek. 1990, 51, 1051 – 1055.
17.  Ratajczak M.Z., Szczylik C., Jedrzejczak W.W.: Changes in selected parameters of renal function in allogeneic bone marrow recipients. Pol. Tyg. Lek.  1991, 51, 1789 – 1796.
18.  Ratajczak M.Z., Szczylik C., Jedrzejczak W.W.: Changes in selected hepatic parameters in allogeneic bone marrow recipients. Pol. Tyg. Lek. 1993, 48, 276 – 281.
19.  Ratajczak M.Z., Jedrzejczak W.W.: Changes in serum electrolyte concentrations in allogeneic bone marrow recipients. Pol. Tyg. Lek. 1992, 52, 125 – 132.
20.  Ratajczak M.Z., Karwacki M.: Cardiac and endocrine complications in patients after bone marrow transplantations (review).  Pol. Tyg. Lek. 1991, 52, 221 – 227.
21.  Ratajczak M.Z., Szczylik C.: Negative hematopoietic regulators (editorial review). Pol. Tyg. Lek. 1992, 5-6, 115-119.
22. Szczylik C., Panasiuk E., Urbanowska E., Ratajczak M.Z., Wankowicz Z.: The effect of dialysing fluids with varying pH values and buffer types used in peritoneal dialysis on the system of peritoneal phagocytes. Experimental part.  Pol. Arch. Med. Wew. 1990, 84, 138 – 143.
23. Szczylik C., Knap J., Badowski A., Ratajczak M.Z., Siekierzynski M.: Interleukin – 2 (IL-2) in the treatment of malignant melanoma. A case report. Pol. Arch. Med. Wew. 1990, 84, 328 – 334.
24.  Ratajczak M.Z., Hijiya N., Catani L., Zhang J., Gewirtz A.M.: The protoncogen c-kit is expressed by human melanoma cell lines. Pol. Tyg. Lek. 1992, 48-49, 938-941.
25. Ratajczak M.Z., Luger S.M., Gewirtz A.M.: The role of c-kit protoncogene in human hemopoiesis (review).  Post. Biol. Kom. 1992, 3, 203-243.
26.  Ratajczak M.Z., Skorski T.: Potential application of oligodeoxynucleotides in clinical medicine. (Editorial Review). Pol. Tyg. Lek. 1992, 48-49, 913-917.
27.  Ratajczak M.Z., Ratajczak J., Kuczynski W.I.: The influence of different hematopoietic growth factors on human granulocyto – monocytopoietic colony growth in vitro. Clinical implications.  Pol. Tyg. Lek. 1993, 48, 511 – 513.
28.  Ratajczak J., Kuczynski I.W., Ratajczak M.Z.: The influence of different hematopoietic growth factors on human megakaryocytic colony growth. Clinical Implications. Pol. Arch. Med. Wewn. 1994, 91, 356-362.
29.  Ratajczak M.Z., Gewirtz A.M.: The role of the receptors with intrinsic tyrosine kinase activity in the regulation of human haematopoiesis. Post. Biol. Kom. 1993, 3, 279-295.
30.  Ratajczak M.Z., Ratajczak J., Kuczynski W.I., Skorski T.: The influence of Interleukin – 1a  on the human erythropoiesis in vitro – its potential role in the pathogenesis of anemia of chronic disease. Pol. Arch. Med. Wewn. 1994, 91, 97 – 104.
31.  Ratajczak M.Z., Ratajczak J.: The pathogenesis of the anemia of chronic disease. The influence of cachectin (TNF-a) and (limfotoxin) TNF-b on human erythropoiesis in vitro. Pol. Tyg. Lek. 1994, 49, 280 – 283.
32.  Ratajczak M.Z., Ratajczak J.: The influence of IL-8 on the human hematopoiesis in vitro. Acta. Haematol. Pol. 1994, 25, 269 – 275.
33.  Ratajczak M.Z.: Molecular mechanisms regulating human erythropoiesis. Clinical implications. Acta Haematol. Pol. 1994, 25 suppl 1, 41-49.
34.  Ratajczak M.Z., Skorski T.: The perspectives of antisense strategies in the experimental and clinical medicine. Post. Biol. Kom. 1994, 21, 177 – 196.
35.  Jedrzejczak W.W, Szczylik C., Ratajczak M.Z.: Health status of the allogeneic bone marrow transplant recipients. Pol. Tyg. Lek. 1993, 48, 543-545.
36.  Ratajczak M.Z.: Perspectives of the practical application of advances of biotechnology, molecular biology and cellular engineering in clinical haematology. (Editorial paper). Pol. Arch. Med. Wew. 1994, 92, 373-379.
37.  Ratajczak M.Z., Kuczynski W.I.: The application of antisense oligodeoxynucleotides strategy in studies on molecular regulation of haematopoiesis. Biotechnologia, 1995, 1(28), 56 – 64.
38.  Ratajczak M.Z., Skorski T., Bialek M.: The perspectives of application of antisense strategies in the clinical medicine. Biotechnologia , 1995, 1 (28), 35 – 43.
39.  Ratajczak J., Ratajczak M.Z., Kuczynski W.: The influence of IL-11 on human erythropoiesis in vitro. Potential clinical implications. Pol. Arch. Med. Wewn., 1995, 93, 461-467.
40. Ratajczak J., Halasa M., Ratajczak M.Z.: The influence of macrophage inflammatory protein – 1a on human erythropoiesis in vitro. Clinical implications. Acta Haematol. Pol. 1995, 26, 171 – 177.
41.  Ratajczak M.Z., Halasa M., Kuczynski W.: The role of STK-1 receptor ligand in the regulation of human and murine hematopoiesis. Post. Biol. Kom. 1995, 22, 131-147.
42.  Ratajczak M.Z., Marlicz W., Ratajczak J., Skorski T.: Characterization, isolation and application of human early hematopoietic cells in clinical medicine – transplantological implications. Post. Biol. Kom. 1995, 22, 207-234.
43.  Ratajczak M.Z.: Molecular mechanisms regulating the proliferation of the earliest human hematopoietic cells. Acta Haematol. Pol. 1995, 26, 34-43.
44.  Ratajczak J., Marlicz W., Ratajczak M.Z.: The influence of human recombinant ligand of STK-1R (FLK2/FLT3) on human erythropoiesis in vitro. Potential clinical implications. Pol. Arch. Med. Wewn. 1995, 94, 418-424.
45.  Machalinski B., Grzegrzolka R., Ratajczak M.Z. Evaluation of the toxicity of rhodamine123 (Rh123) against human hematopoietic progenitor cells. Acta. Haematol. Pol. 1997, 28, 137-145.
46. Ratajczak J., Machalinski B., Pluciennik E., Halasa M., Ratajczak M.Z.: Influence of neutrophils activating peptide-2 (NAP-2) on human erythropoietic progenitors growth in vitro. Studies relevant to the pathogenesis of the anemia of chronic diseases. Acta Haematol. Pol. 1997, 28, 125-135.
47.  Ratajczak M.Z.: Biology and methods for isolating and ex vivo expanding of human early hematopoietic cells. Clinical implications. Acta Haematol. Pol. 1997, 28 supl 2, 132-137.
48.  Machalinski B., Marlicz W., Pluciennik E., Ratajczak J., Ratajczak M.Z.: The influence of thrombopoietin on human erythropoiesis. Studies in vitro – clinical implications. Pol. Arch. Med. Wewn. 1997, 97, 307-315.
49.  Machalinski B., Ratajczak M.Z.:  Evaluation of the toxicity of selected anticoagulants on clonogenecity of human hematopoietic progenitors. Pol. Arch. Med. Wew. 1997, 97, 509-517.
50.  Machalinski B., Ratajczak M.Z.: The toxicity of Hoechst33342 against normal human bone marrow progenitors. Preliminary report. Acta Haematol. Pol. 1997, 28, 433-441.
51.  Machalinski B., Honczarenko M., Gontarewicz A., Ratajczak M.Z.: The isolation of hematopoietic mononuclear cells from bone marrow, peripheral, and cord blood employing Ficoll-Paque (Pharmacia) or Gradisol-L (Polfa, Kutno). Comparison of both methods. Pol. Arch. Med. Wewn. 1998, 99, 15-23.
52. Ratajczak M.Z., Skorski T., Kuczynski W.I., Ratajczak J.: Storage of human bone marrow before transplantation at 4 degrees C. Pol. Merk. Lek. 1998, 4, 143-146.
53.  Machalinski B, Gabriel A, Honczarenko M, Karbicka A, Ratajczak M.Z.: Toxicity of Pyronin Y against human cord blood and bone marrow hematopoietic progenitor cells. Preliminary report.  Acta Haematol. Pol. 1998, 29, 319-326.
54.  Machalinski B, Majka M, Ratajczak M.Z.:  The potential toxicity of the ammonium chloride solution against human normal and malignant hematopoietic cells.  Acta Haematol. Pol. 1998, 29, 461-468.
55.    Ratajczak M.Z., Majka M,  Ratajczak J.: HIV infection and haematopoiesis. Clinical implications. Acta Haematol. Pol. 1999, 30 (suppl 1), 90-98.
56.  Honczarenko M, Machalinski B, Marlicz W, Majka M, Kijowski J, Paczkowski M, Ratajczak J, Ratajczak M.Z.: Ex vivo expansion of human megakaryocytic progenitors as a method for ameliorating chemotherapy or haematopoietic transplant related thrombocytopenias. Onkologia Polska 1998, 3-4, 117-123.
57.  Majka M, Honczarenko M, Kijowski J, Paczkowski M, Gontarewicz A, Paczkowska E, Ratajczak M.Z.: Protoncogene c-MYB regulates telomerase activity in the chronic myeloid leukemia cells. Preliminary report. Onkologia Polska 1998, 3-4, 111-115.
58.  Czajka R, Szolomicka-Kurzawa P, Kurzawa R, Ratajczak MZ. The effect of umbilical cord blood cytokines on clonogenecity of hemopoietic cells isolated from umbilical cord blood. Ginekol. Pol. 1999, 70, 866-872.
59.  Kucia M, Majka M, Ratajczak M.Z. Phenomenon of the plasticity of the tissue committed stem cells. Post. Biol. Kom. 2003, 30, 3-15.
60.  Majka M. Michalowska A, Kucia M, Ratajczak M.Z. Isolation of human skeletal muscle stem cells. Post. Biol. Kom. 2003, 30, 17-24.
61.  Drukala J, Majka M, Ratajczak M.Z. Advances in methods of isolation and expansion of human epidermal stem cells. Post. Biol. Kom. 2003, 30, 37-48.
62.  Drabko K, Choma M, Zaucha-Prazmo A, Wojcik B, Gorczynska E, Kalwak K, Turkiewicz D, Slociak M, Ussowicz M, Dyla A, Chybicka A, Styczynski J, Debski R, Wysocki M, Gozdzik J, Ratajczak M, Kowalczyk JR. Megachemotherapy and autologous hematopoietic stem cell transplantation in children with solid tumours excluding neuroblastoma – experience of polish paediatric centres. Med Wieku Rozwoj. 2006;10:785-792.
63.  Zaucha-Prazmo A, Drabko K, Wojcik B, Choma M, Kalwak K, Gorczynska E, Turkiewicz D, Slociak M, Ussowicz M, Dyla A, Chybicka A, Gozdzik J, Ratajczak M, Styczynski J, Debski R, Wysocki M, Kowalczyk J. High-dose therapy followed by auto HSCT in children – with advanced neuroblastoma in four transplant centres in Poland. Med Wieku Rozwoj. 2006;10:775-784.
64. Zuba-Surma EK, Kucia M, Ratajczak MZ. Image stream technology – a step forward than flow cytometry. Post. Biol. Kom. 2007, 34, 361-375.
65. Ratajczak MZ, Popiela T. Will regenerative medicine become and alternative to resective surgery in gastroenterology. “Editorial” Gastroenterol. Pol. 2009, 16, 351-359.
66.  Klich I, Walat S, Ratajczak J, Kucia M, Ratajczak MZ. Very small embryonic like stem cells (VSELs) isolated from adult tissues – an update. Post. Biol. Kom. 2010, 37, 63-87.
67.  Ratajczak MZ, Machalinski B, Czajka R, Zuba-Surma E, Poziomkowska I, Slowik D. Physiological and pathological consequences of a presence of germ line stem cells in adult tissues. Ginekol. Pol. 2009, 80, 935-941.
68. Krasowska-Kwiecień A, Kijowski J, Łukasiewicz E, Sacha T, Foryciarz K, Majka M, Ratajczak MZ, Skotnicki AB. Angiogenesis in different clinical phases of chronic myeloid leukemia. Przegl. Lek. 2009, 66, 471-478.
69. Poziomkowska I, Słowik-Żyłka D, Słuczanowska S, Grymuła K, Sroczyński T, Staniszewska M, Banach B, Ratajczak MZ. CXCR7 a new receptor for stromal derived factor-1 (SDF-1). Post. Biol. Kom. 2010 (in press).
70.  Piotrowska K, Sluczanowska-Glabkowska S, Ratajczak MZ.  Potential application of germ line stem cells in regenerative medicine. Post. Biol. Kom. 2010, 37, 765-781.
71.  Ratajczak MZ, Suszynska M. Quo Vadis medycyno regeneracyjna? Acta Haeamtol. Pol. 2013, 44, 161-170.
72. Tarnowski M, Grymuła K, Tkacz M, Czerewaty M, Poniewierska-Baran A, Ratajczak MZ. Molecular mechanisms regulating metastasis of cancer cells with special emphasis on rhabdomyosarcoma. Postepy Hig Med Dosw, 2014, 68, 258-70.

 

PUBLISHED ABSTRACTS (Selected)

More than 400 papers presented at national and international congresses and symposia. The abstracts were printed in Abstract Books and some of them in journals such as:  Blood,  Experimental Hematology, Blut, International Journal of Radiation Biology, Clinical Research, International Journal of Cell Cloning.

Selected Abstracts from the last 15 years:

AAP/ASCI/AFCR Annual Meeting 1991, Seattle
1.     Ratajczak M.Z., Shen, Y.M., Gewirtz A.M.: Role of c-kit protooncogene in human in vitro hematopoiesis. Clin.Res. 1991, 39, 190.

 

Molecular Biology of Hematopoiesis 1991, Innsbruck
2.     Ratajczak M.Z., Gewirtz A.M.: Role of c-kit proooncogene in normal and  malignant human hematopoiesis. Int. J. Cell Clon. 1991, 9, 335.

 

American Society of Hematology, 33rd Annual Meeting, 1991, Denver
3.     Ratajczak M.Z., Gewirtz A.M.: Regulation and function of the c-kit protooncogene in normal human hematopoiesis. Blood 1991, 78, Suppl 1, 161 a.
4.     Luger S.M., Ratajczak M.Z., Abrahm J., Gewirtz A.M.: Role of the c-kit protooncogene in malignant human hematopoiesis. Blood 1991, 78 Suppl, 1, 270 a.
5.     Hijiya N., Ikegaki U., Ratajczak M.Z., DeRiel K., Gewirtz A.M.:  Malignant melanoma and neuroblastoma cell lines growth is inhibited by c-myb antisense oligodeoxynucleotides. Blood 1991, 78 Suppl 1, 334 a.
6.     Parker R.I., Siegel R.S., Ratajczak M.Z., Gewirtz A.M.: Deficient in vitro megakaryocytopoiesis and desreased in vivo platelet turnover in chronic thrombocytopenia. Blood 1991, 78 Suppl 1, 131 a.

 

Jahrestagung der Deutschen Gesellschaft fuer Haematologie und Onkologie

Berlin 1992:
7.     Ratajczak M.Z., Gewirtz A,M.: Antisense oligodeoxynucleotides as probes for studying human hematopoiesis (Plenar Lecture). Annals of  Hematology 1992, 65 Suppl 1, A 107.

 

International Conference on Gene Therapy  of Cancer. San Diego 1992, California.
8.     Luger S., Ratajczak M.Z., Abrams E., Stadtmauer E., Gewirtz A.:  Targeted disruption of the c-kit protoncogene with antisense oligodeoxynucleotides: biologic consequences and potential therapeutic applications. Human Gene Therapy 1992, 5, 613.

 

American Society of Hematology,  34th  Annual Meeting, 1992, Anaheim, CA.
9.     Ratajczak M.Z., Kant J.A., Luger S,M., Hijiya N., Zhang J., Zon G., Gewirtz  A.M.: In vivo treatment of human leukemia in a SCID mouse model with c-myb antisense oligodeoxynucleotides. Blood 1992, 80, Suppl 1,156 a.
10. Ratajczak M.Z., Kuczynski W.I., Moore J., Ratajczak J., Gewirtz A.M.: A reapraisal of the function of insuline like growth factor -1 (IGF – 1) in the regulation of normal human erythropoiesis. Blood 1992, 80, Suppl 1, 151 a.
11. Luger S.M., Ratajczak M.Z., Abrams J., Stadtmauer E., Gewirtz A.M.: In vitro sensitivity of myeloproliferative disorder colony forming units to c-myb and c-kit antisense DNA: a two year cumulative experience. Blood 1992, 80, Suppl 1,156 a.

12. Skorski T., Nieborowska – Skorska M., Ratajczak M.Z., Barletta C., Szczylik C., Lange B., Gewirtz A.M., Calabretta B.: Highly efficient purging of Philadelphia1 leukemic cells from bone marrow cells by exposure to bcr-abl antisense oligodeoxynucleotides combined with mafosfamide. Blood 1992, 80, Suppl 1, 199 a.
13. Takeshita K., Bollekens J.A., Hijiya N., Ratajczak M., Gewirtz  A.M., Ruddle F.H.: Homeobox gene Hox 3 C is required for erythropoiesis. Blood 1992, 80, Suppl 1, 346 a.
American Association of Cancer Research, Orlando, Florida, 1993.

14. DiPaola R.S., Onodera K., Kuczynski W., Ratajczak M.Z., Hijiya N., Gewirtz A.: Growth imhibition of non-small cell lung cancer with  c-kit antisense oligodeoxynucleotides. Proceedings Am. Assoc. Canc. Res. 1993, 2319.
15. Hijiya N., Zhang J., Ratajczak M.Z., Herlyn M., Gewirtz A.M.:  C-myb antisense oligodeoxynucleotides inhibit human melanoma growth in vitro and in vivo. Proceedings Am. Assoc. Canc. Res. 1993, 2318.

 

American Association of Clinical Investigation, Washington DC, 1993.
16.         Ratajczak M.Z., Ratajczak J., Kuczynski W., Light B., Gewirtz A.M.: In vitro sensitivity of human hemopoietic progenitor cells to 4-Hydroperoxycyclophosphamide. Clin. Res. 1993, 41, 308 A.

 

Symposion to memory of Rudolf Virchow, Szczecin, Poland, 1993.
17. Ratajczak M.Z., Gewirtz A.M.: Antisense strategy. The perspectives of therapeutical use of antisense oligomers in the treatment of human leukemias. (Plenary lecture).

 

V Annual Conference on Cell Biology, 1993, Wroclaw, Poland.
18. Ratajczak M.Z.: The role of receptors with intristinic tyrosine kinase activity in regulation of normal human haematopoiesis.  (Plenary lecture).

 

American Society of Hematology, 35th Annual Meeting, December 1993  St. Louis, Missouri, USA.:
19. Ratajczak M.Z., Gewirtz A.M.: The human c-kit gene 5′ region:  sequence analysis and functional characterization. Blood 1993, 82 suppl 1, 229 a.
20. Ratajczak M.Z., Kuczynski W.I., Ratajczak J., Light B., Luger S,M,. Gewirtz A.M.: A simple. efficient method for cryopreserving bone marrow cells in a -80oC mechanical freezer. Blood 1993, 82 suppl 1, 652 a.
21. Kuczynski W.I., Ratajczak M.Z., Gewirtz A.M.: Stem cell kinase-1 (STK-1), human homologue of the murine FLT3/KLK2 tyrosinase kinase receptor gene, is expressed on a wide variety on non-hematopoietic tumor cell types. Blood 1993, 82 suppl 1, 486 a.
22. Luger S.M., Ratajczak M.Z., DiPaola R., Gewirtz A.M.: Functional requirement for the vav protooncogene product, p95vav in the human hematopoiesis. Blood 1993, 82 suppl 1, 107 a.
23. Small D., Levenstein M., Kim E., Carow C.E., Amin S.,  Ratajczak M.Z., Gewirtz A.M., Civin C.I.: STK-1, a human homolog  of FLK2/FLT3, is aberrantly expressed in human leukemias and  may be involved in the growth and/or differentiation of hematopoietic stem/progenitor cells. Blood 1993, 82 suppl 1, 325 a.

 

Conference of the Polish Society of Haematology and Transfusiology. Wroclaw 1994.

24.  Ratajczak M.Z.: Molecular mechanisms of the regulation of the human erythropoiesis. Clinical implications (Plenar Lecture). Acta Haematol. Pol. 1994, 25 suppl 1, 41-49.
25. Ratajczak M.Z., D.A. Kregenow,  A.M. Gewirtz. The human c-kit gene 5′ region: sequence analysis and functional characterization. Acta Haematol. Pol 1994, 25 suppl 1.
26. Ratajczak M.Z.,  J. Ratajczak, W. Kuczynski,  A. Gewirtz:   The cryopreservation of bone marrow CD34+ cells in a mechanical freezer at -80oC. Evaluation of the freezing, storage and thawing procedures. Acta Haematol. Pol 1994, 25 suppl 1.
27. Ratajczak J., D. Kregenow, W.I. Kuczynski and M.Z. Ratajczak: Anemia of chronic disease. The influence of TNF-a and TNF-b on human hematopoiesis in vitro. Acta Haematol. Pol 1994, 25 suppl 1.
28. Ratajczak M.Z.,  J. Ratajczak, W. Kuczynski, A. Gewirtz: Stimulation of the human bone marrow CD34+ cells with KL, IL-3  and IL-1b prior to freezing enhances their survival and post- thawing proliferative potential. Acta Haematol. Pol 1994, 25 suppl 1.
29. J. Ratajczak and M.Z. Ratajczak. Anemia of chronic disease. The influence of IL-8 on human hematopoiesis in vitro. Acta Haematol. Pol 1994, 25 suppl 1.
30. J. Ratajczak and M.Z. Ratajczak: Anemia of chronic disease. The influence of IL-6 on human hematopoiesis in vitro. Acta Haematol. Pol 1994, 25 suppl 1.
31. W. Kuczynski, J. Ratajczak and M.Z. Ratajczak: Short – term storage of the human bone marrow cells in refrigerator at 4oC. Optimalization of the procedure. Acta Haematol. Pol 1944, 25 suppl 1.
32. J. Ratajczak, W. Kuczynski, M.Z. Ratajczak: Anemia of  chronic disease. The influence of IL-1 on human hematopoiesis in vitro. Acta Haematol. Pol 1994, 25 suppl 1.

 

First Berlin Symposium on „The application of molecular biology to cancer patients”.  Berlin 1994.
33. M.Z. Ratajczak, Gewirtz A.M.:  Oligodeoxsynucleotide-based therapeutics of human leukemias.  (Plenar lecture).

 

Conference on Bone Marrow Transplantation in Poland, Warsaw 1994.
34. Ratajczak M.Z.: Isolation, storage and expansion of CD34+ bone marrow cells. Transplantological implications.  (Plenar lecture).
35. Jedrzejczak W.W., Szczylik C., Ratajczak M.Z., Pojda Z., Szwech P.: Evaluation of late complications of the allogeneic bone marrow transplantations.  (Plenar lecture).

 

36th Annual Meeting of the American Society of Hematology, Nashville, December 1994:
36.  M.Z. Ratajczak, W.I. Kuczynski, J. Moore, A.M. Gewirtz.: Facs sorted human CD34+ bone marrow cells coexpress c-kit ligand (KL) and stem cell tyrosine kinase-1 receptor ligand (STK-1L). Blood 1994, 84, Suppl 1, 370a.
37. M.Z. Ratajczak, M.T. Mitjavilla, J. Ratajczak, W. Kuczynski, D. Kregenow, A.M. Gewirtz.: Human erythropoiesis in a serum free culture system: a reappraisal of the role of insulin. Blood 1994, 84, Suppl 1, 281a.
38. Luger S.M., Ratajczak M.Z., Stadtmauer E.A., Mangan P., Magee D., Silberstein L., Edelstein M., Nowell P., Gewirtz A.M.: Autografting for chronic myelogeneous leukemia (CML) with c-myb antisense oligodeoxynucleotide purged bone marrow: a preliminary report. Blood 1994, 84, Suppl 1, 151a.

 

Antisense Therapy – International IBC Conference. Charing Cross Medical School, London 1995.
39. Ratajczak M.Z., Gewirtz A.M. Oligonucleotide therapeutics for human leukemias (Plenary lecture).

 

The Treatment of Cancer: Beyond Chemotherapy. IBC International Conference, London 1995.
40. Ratajczak M.Z., Gewirtz A.M. Oligonucleotide therapeutics for human leukemias (Plenary lecture).

 

XVI Meeting of Polish Society of Haematology and Transfusiology. Warsaw, 1995.
41. Ratajczak M.Z.: Molecular mechanisms regulating the proliferation of the earliest human hematopoietic cells. (Plenary Lecture).
42. Kuczynski WI, Ratajczak M.Z.: Influence of interferon- on c-kit R expression.
43. Kuczynski WI, Ratajczak M.Z.:  The role of EpO in human megakaryopoiesis.

 

Annual Scientific Meeting of the British Society for Haematology. Brighton 1995.
44. O’Brien S.G., Rule S., Ratajczak M.Z., Luger S.M., Goldman J.M., Gewirtz A.M.: Autografting for CML using bone marrow purged with myb antisense oligonucleotide. Brit. J. Haematol. 1995, 89, (Suppl 1), 12.

 

XXIV th Annual Meeting of the International Society for Experimental Hematology. Dusseldorf 1995.
45. O,Brien S.G., Gewirtz A.M., Rule S.A., Hawkins T.E., Ratajczak M.Z., Savage D., Luger S.M., Goldman J.M.: Autografting for CML using bone marrow purged with myb antisense oligonucleotide. Exp. Hematol. 1995, 22, 804.

 

3th Annual Meeting  of The Polish Section of the European Cell and Tissue Culture Society. October, Krakow 1995.
46. Ratajczak M.Z.: Contemporary methods of investigation of the molecular mechanisms regulating the proliferation and differentiation of human hemopoietic stem and progenitor cells. (Plenary lecture).

 

37th Annual Meeting of the American Society of Hematology, Seattle, December 1995:
47. Luger S.M., Ratajczak J., Ratajczak M.Z.,  DiPaola R., Clevenger R., Gewirtz A.M.: Role of the p95vav  protooncogene in normal and malignant human hematopoiesis. Blood 1995, 86 suppl 1, 146a.
48. Ratajczak M.Z., Ratajczak J., Marlicz W., Ford J., Kregenow D., Gewirtz A.M.: Stem cell tyrosine kinase-1 ligand (STK-1L) does not stimulate human megakaryocytopoiesis in vitro. Blood 1995, 86 suppl 1, 907a.
49. Ratajczak J., Ratajczak M.Z., Gewirtz A.M.: Ex vivo expansion of human megakaryocyte progenitor cells in vitro. Blood 1995, 86 suppl 1, 363a.
50. Ratajczak M.Z., Ratajczak J., Marlicz W., Moore J., Gewirtz A.M.: A kinetic and functional analysis of receptors with intrinsic tyrosinase activity in normal human hematopoietic progenitor cells. Blood 1995, 86 suppl 1, 259a.

 

Annual Conference on Bone Marrow Transplantation. Poznan, June 1996.
50. Ratajczak M.Z.: The biology of human hematopoietic stem cells. Transplantological implications. (Plenary Lecture).
51. Marlicz W., Machalinski B., Gewirtz A.M., Ratajczak M.Z.: Serum free system for expanding ex vivo human hematopoietic cells.
52. Marlicz W., Machalinski B., Gewirtz A.M., Ratajczak M.Z.: Long term storage of human CD34+ cells in -80oC mechanical freezer.
53. Marlicz W., Ratajczak M.Z.: Toxcicity of the different nonviral transfection methods aginst human CD34+ progenitor cells.
54. Marlicz W., Ratajczak M.Z.:  Effectivity of different methods for isolating human CD34+ cells.

 

Conference on Cellular Interactions. Poznan, September 1996.
55. Ratajczak M.Z.: The role of receptors possesing intrinsic tyrosine kinase activity in regulating of the human earliest heamtopoietic cells. (Plenary Lecture).
56. Ratajczak M.Z.: Pathogenesis of the anemia of chronic disorders. (Plenary Lecture).
57. Ratajczak M.Z., Pletcher Ch., Marlicz W., Wasik M., Machalinski B., Ratajczak J., Moore J., Gewirtz A.M.: A rapid method for isolating human hematopoietic stem cells. Abstracts.

 

38th Annual Meeting of the American Society of Hematology, Orlando, December 1996:
58. Ratajczak M.Z., Pletcher Ch., Marlicz W., Wasik M., Machalinski B., Ratajczak J., Moore J., Gewirtz A.M.: A rapid method for isolating human hematopoietic stem cells (HHSC). Blood 1996, 88 Suppl 1, 109a.
59.  Gewirtz A.M., Luger S., Sokol D., Gowdin B., Stadtmauer E., Reccio A., Ratajczak M.Z.: Oligodeoxynucleotide therapeutics for human myelogenous leukemia.  Blood 1996, 88 Suppl 1, 270a.
60. Ratajczak M.Z., Machalinski B., Ratajczak J., Skorski T., Marlicz W., Gewirtz A.M.: In vitro and in vivo evidence that ex vivo cytokine priming of transplanted marrow cells may ameliorate post-transplant thrombocytopenia. Blood 1996, 88 Suppl 1, 299a.
61.  Ratajczak M.Z.,  Marlicz W., Ratajczak J., Machalinski B., Wasik M., Gewirtz A.M.: Role of c-met receptor (MET-R)/hepatocyte growth factor (HGF) axis in human hematopoiesis. Blood 1996, 88 Suppl 1, 538a.

 

2nd Symposium of Tissue Cultures of Central European Countries. Krakow, Poland June 1997:
62. Ratajczak M.Z. The biology of human hematopoietic stem and progenitor cells (Plenary lecture). Folia Histochem. et Cytobiol. 1997, 35 suppl.2, 7.
63. Ratajczak M.Z. A new trends for isolating, ex vivo expanding, and cloning of human early hematopoietic cells (Plenary lecture). Folia Histochem. et Cytobiol. 1997, 35 suppl.2, 23.

 

XVII th Congress of the Polish Society of Haematology and Transfusiology, Krakow, Poland, September

1997.
64. Ratajczak M.Z. A new strategies for isolating and ex vivo expanding of human early hematopoietic cells. Clinical implications.  (Plenary lecture). Acta Haematol. Pol. 1997, 28 supl 2, 132-137.

 

Annual Symposium on Advances of Cytometry in Clinical Medicine, Poznan, Poland, September 1997.
65. Ratajczak M.Z.  The application of FACS for studying the expression of the intracellular proteins. (Plenary lecture).
66. Ratajczak M.Z. The application of FACS for isolating human earliest hematopoietic cells. (Plenary lecture).

 

39th Annual Meeting of the American Society of Hematology, San Diego, December 1997:

67. Ratajczak M.Z., Lee B., Ratajczak J., Doms R., Gewirtz A.M.: Characterization and biologic consequence of chemokine (CXCR4, CCR5 and CCR3) receptor and CD4 antigen expression on normal and malignant human hhematopoietic cells. Blood 1997, 90 suppl 1, 476a.
68. Ratajczak J., Lee B., Gewirtz A.M., Ratajczak M.Z.: In vitro studies on the pathogenesis of AIDS related anemia. Blood 1997, 90 suppl 1, 18b.
69. Machalinski B., Pluciennik E., Samuel A.A., Francois H., Czajka R., Gewirtz A.M., Ratajczak M.Z.: A convenient and economical method for long distance shipment of non frozen human mononuclear cord blood cells. Blood 1997, 90 suppl 1, 330b.
70. Ratajczak J., Ratajczak M.Z., Mick R., Vaughn D., Gewirtz A.M.: Paclitaxel/carboplatin chemotherapy: examining its platelet sparing mechanism. Blood 1997, 90 suppl 1, 205b.
71. Hung H.L., Song F., Davis M., Ratajczak M.Z., Gewirtz A.M.: Thrombopoietin upregulates Set and eIF-5A mRNA transcripts in later megakaryocyte progenitor. Blood 1997, 90 suppl 1, 46a.
72. Gewirtz A.M., Ratajczak M., Vilaire G., Bennet J.: Effect of integrin mediated signaling on c-myb expression in human hematopoietic cells. Blood 1997, 90 suppl 1, 484a.
73. Ratajczak M.Z., Ratajczak J., Machalinski B., Pietrzkowski Z., Sokol D., Carter A., Gewirtz A.M. Role of vascular endothelial growth factor (VEGF), placenta derived growth factor (PlGF)/FLK-1/KDR, and FLT-1 receptor axes in human fetal and adult hematopoiesis. Blood 1997, 90 suppl 1, 572a.
74. Kowalska A., Ratajczak MZ, Ratajczak J, Hoxie J, Brass L., Vilaire G., Bennet J., Gewirtz AM. Megakryocytes and platelets express the HIV co-receptor Fusin (CXCR4) on their surface. Blood 1997, 90 suppl 1, 283a.
75. Zhang Q., Wang ZY, Sun X, Ratajczak MZ, Wasik M. Constitutive phosphorylation of receptor for IGF-I (IGF-IR) in malignant T-cell lymphoma cells. Blood 1997, 90 suppl 1, 74a-75a.
76. Wlodarski P., Wasik M., Ratajczak M.Z., Sevignani C., Hoser G., Kawiak J., Gewirtz A.M., Calabretta B., Skorski T. Role of p53 in hematopoietic recovery after cytostatic treatment. Blood 1997, 90 suppl 1, 479a.
77. Sesok-Pizzini D., Ratajczak MZ, Moore J, Jefferies L., Wilson R. Kell protein expression during fetal erythropoiesis. Blood 1997, 90 suppl 1, 472a.

 

40 th Annual Meeting of the American Society of Hematology, Miami, December 1998:
78. Lee B., Sharron M., Tsang M., Majka M.M., Ratajczak M.Z., Montaner L.J.,  Weissman D., Doms R.W. Quantification of CD4, CCR5, CXCR4, and STRL33 levels on differentially conditioned monoyte-derived macrophages, vatious subsets of oeripheral blood leukocytes and CD34+ bone marrow progenitor cells. Blood 1998, 92 suppl 1, 663a.
79. Majka M., Lee B., Ratjczak J., Pertusini E., Honczarenko M., Kowalska M.A., Wasik M.A., Gewirtz A.M., Ratajczak M.Z. Expression and function of HIV-1 co-receptors on human hematopoietic cell lines. Blood 1998, 92 suppl 1, 671a.
80. Majka M., Honczarenko M., Ratajczak J., Lee B., Kowalska M.A., Douglas R., Poncz M., Silberstein L., Gewirtz A.M., Ratajczak M.Z. The expression of chemokine reseptors during erythroid differentiation oh human CD34+ cells. The role of chemokines on calcium flux, chemotaxis and proliferation. Blood 1998, 92 suppl 1, 1508a.
81. Pertusini E., Ratajczak J., Majka M., Ratajczak M.Z., Vaughn D., Gewirtz A. Elucidation of the platelet sparing mechanism of paclitaxel/carboplatin chemotherapi. Blood 1998, 92 suppl 1, 1598a.
82. Ratajczak J., Majka M., Pletcher Ch., Moore J., Ratajczak M.Z. Evidence that human hematopoietic stem cells (HSC) do not reside within the CD34+, KIT- cell population. Blood 1998, 92 suppl 1, 1823a.
83.  Ratajczak J., Gewirtz A.M., Ratajczak M.Z.  Role of c-KIT and c-MYB in inhibiting apoptosis and regulating telomerase activity in early human erythroid progenitors. Blood 1998, 92 suppl 1, 2083a.
84. Majka M., Ratajczak J., Pizzini D., Gewirtz A.M., Ratajczak M.Z. Expression, regulation, and function of AC133, a putative cell surface determinant of primitive human hematopoietic cells. Blood 1998, 92 suppl 2, 3601a.
85. Machalinski B., Rozewicka L., Ratajczak M.Z. In vitro and in vivo studies on the potential toxicity of the metabolical fluorochromes-Rhodamine 123 (Rh123), Pyronin Y (PyY) and Hoechst 33342 (Hoe342). Practical implications for stem cell isolation. Blood 1998, 92 suppl 1, 4301a.
86. Marlicz W., Kijowski J., Machalinski B., Paczkowski M., Gontarewicz A., Paczkowska E., Ostrowski M., Gewirtz A.M., Ratajczak M.Z. Heparinized cadaveric multiple organ donors (HCMOD) a forgotten source of hematopoietic cells for transplantation – a time to create n universal stem cell bank for needs of the XXI century. Blood 1998, 92 suppl 1, 4303a.
87. Majka M., Pertussini E., Ratajczak J., Pletcher Ch., Pizzini D., Ratajczak M.Z. Removing nucleated erythroblasts (NEB) from cord blood mononuclear cell preparations: practical implications for the preparation of cord blood samples for high speed sorting. Blood 1998, 92 suppl 1, 4348a.

 

XVIII th Congress of the Polish Society of Haematology and Transfusiology, Lodz, Poland, June1999.
88. Ratajczak MZ, Majka M, Ratajczak J.: “Influence of HIV infection on human hematopoiesis. Clinical implications”. (Plenary Lecture). Acta. Haematol. Pol. 1999,
89. Machalinski B, Marlicz W, Majka M, Ratajczak J, Ratajczak MZ.: The role of neo-angiogenesis in the pathogenesis of CML. Acta Haematol. Pol. 1999,
90. Machalinski B, Marchlewicz M, Dziedziejko V, Wiszniewska B, Machoy Z, Wenda-Rozewicka L, Ratajczak MZ. The influence of sodium fluoride (NaF) on hematopoiesis. Studies in vitro and in vivo. Acta Haematol. Pol. 1999,
91. Ratajczak J, Majka M, Ratajczak M.Z.: The role of kit ligand – kit receptor – cymb protoncogene axis in inhibiting apoptosis and regulating telomerase activity in human erythroid progenitor cells. Acta Haematol. Pol. 1999,
92. Kijowski J, Marlicz W, machalinski B, Paczkowski M, Gontarewicz A, Turkiewicz W, Ostrowski M, Zukowski M, Bohatyrewicz Z, Wlodarczyk K, Ratajczak M.Z.: Heparinized cadaveric multiple organ donors (HCMOD) a forgotten source of hematopoietic stem cells. Potential clinical implications.  Acta. Haematol. Pol. 1999,
93. Marlicz W, Ratajczak MZ.: The comparison of the various physico-chemical methods for introducing antisense oligomers and plasmid DNA into the hematopoietic cells. Acta. Haematol. Pol. 1999,
94. Majka M, Machalinski B, Ratajczak M.Z.: Expression, regulation, and function of AC133, a putative cell surface marker of primitive human haematopoietic cells. Acta. Haematol. Pol. 1999,
95. Marlicz W, Machalinski B, Majka M, Honczarenko M, Kijowski J, Paczkowski M, Ratajczak J, Ratajczak M.Z.: Ex vivo expansion of human megakaryoblasts and megakaryocytic progenitors as a strategy to ameliorate posttransplant related thrombocytopenia. Acta. Haematol. Pol. 1999,
96. Machalinski B, Ratajczak M.Z.: The toxicity of metabolic fluorochromes: rhodamine 123, Hoechst 33342 and pyronin Y against human hematopoietic progenitor cells. Clinical implications. Acta. Haematol. Pol. 1999,
97. Marlicz W, Ratajczak M.Z.: Toxicity of various physico-chemical methods of transfection against human hematopoietic cells. Acta. Haematol. Pol. 1999,
98. Majka M, Machalinski B, Ratajczak M.Z.: Removing nucleated erythroblasts (NEB) from cord blood mononuclear cell preparations: practical implications for the preparation of cord blood samples for high speed sorting. Acta. Haematol. Pol. 1999,

 

41st Annual Meeting of the American Society of Hematology, New Orleans, December 1999.
99.   Majka M, Rozmyslowicz T,  Lee B,  Honczarenko M,  Pietrzkowski Z, Gaulton GN, Silberstein L, Ratajczak M.Z.:  Bone marrow CD34+ cells and megakaryoblasts secrete b-chemokines. Implications for infectability by M-tropic Human Immunodeficiency Virus (R5 HIV). Blood 1999, 94 suppl 1, 435a.
100. Majka M, Hershock D,  Ratajczak J, Gontarewicz A, Gewirtz AM,  Ratajczak M.Z.: Differentiating normal human megakaryoblasts express APO-Fas (CD95), TNF-RII, secrete several megakaryopoietic inhibitors and undergo apoptosis; An important role of thrombopoietin  (TPO), MYB and PI3K-AKT-BAD axis in inhibiting apoptosis in normal megakaryocytic precursors. Blood 1999, 94 suppl 1, 482a.
101. Majka M,  Ratajczak J,  Pizzini D, Wasik MA, Gewirtz AM, Ratajczak M.Z.: Expresion, regulation, and function of  AC133, a putative cell surface marker of primitive human hematopoietic cells. Blood 1999, 94 suppl 1, 559a.
102. Majka M, Ratajczak J, Vilaire G, Kowalska MA, Ratajczak M.Z.: Binging of stromal derived factor-1a (SDF-1a) to CXCR4 chemokine receptor in normal human megakaryoblasts but not in platelets phosphorylates mitogen-activated protein kinase p42/44 (ERK-1, ERK-2) and p38, serin/threonine kinase AKT, STAT3 and ELK-1 transcription factor.  Blood 1999, 94 suppl 1, 217a.
103. Silberstein LE, Honczarenko M, Mathias C, Majka M, Pietrzkowski Z, Ratajczak MZ.: MIP-1b induced heterologous desensitization of CXCR-4 mediated signaling on early lineage B cells in human bone marrow. Blood 1999, 94 suppl 1, 5a.
104.  Kowalska MA, Majka M, Ratajczak M.Z., Brass LF, Poncz M.: Stromal-derived factors 1 (SDF-1) and macrophage-derived chemokine (MDC): complementary chemokines invloved in platelet activation. Blood 1999, 94 suppl 1, 217a.
105. Giannola DM, Shlomchik D, Ratajczak MZ, Danet G, Liebowitz DN, Emerson SG.: Activation of the human HOXB4 promoter in CD34+ cells is induced during cytokine stimulation favoring self-renewal, via the bHLH-ZIP transcription factor USF-1. Blood 1999, 94 suppl 1, 469a.
106. Majka M, Rozmyslowicz T, Honczarenko M, Lee B, Ratajczak J, Wasik M, Gaulton GN, Gewirtz AM, Silberstein LE, Ratajczak M.Z.: Biological significance of the expression of  HIV related chemokine coreceptors (CCR5 and CXCR4) and endogenous secretion of chemokines by human hematopoietic cell lines. Blood 1999, 94 suppl 1, 618a.
107. Machalinski B, Marlicz W, Paczkowski M, Kijowski J, Gontarewicz A, Ostrowski M, Ratajczak M.Z.: Heparinized cadaveric organ donors (HCOD) – a potential source of cells for hematopoietic transplants and gene therapy. Blood 1999, 94 suppl 2, 322b.
108. Majka M,  Ratajczak J, Ehrenman K,   Pietrzkowski Z,  Emerson SG, Ratajczak M.Z.:  Normal human CD34+ cells and ex vivo expanded myeloblasts, megakaryoblasts and erythroblasts secrete various growth factors, cytokines and chemokines: biological significance of endogenous secretion. Blood 1999, 94 suppl 1, 465a.
109. Majka M,  Ratajczak J, Poncz M, Gewirtz AM, Kowalska MA, Ratajczak M.Z.: Similar but distinct effects of thrombopoietin (TPO) and stromal derived factor-1 (SDF-1) on megakaryopoiesis. Blood 1999, 94 suppl 1, 267a.
110. Majka M, Kowalczyk D, Gee M, Wertheim J, Marquez LA, Pear W, Gewirtz AM, Janowska-Wieczorek A, Emerson SG, Ratajczak M.Z.:  Evidence that both human and murine bcr-abl+ cells stimulate vasculogenesis in vivo in matrigel implants: potential therapeutic implications. Blood 1999, 94 suppl 1, 100a.

 

42nd Annual Meeting of the American Society of Hematology, San Francisco, December 2000.
111.  M. Majka, T. Rozmyslowicz, G. Gaulton, A. Janowska-Wieczorek, Ratajczak M.Z Normal CD34+ cell secrete interleukin-16 and HIH related b-chemokines which contribute to the resistance of CD34+ cells to infection by Human Immunodeficiency virus (R5 and X4 HIV)..Blood 2000, 96 supp 1.
112. J. Kijowski M. Baj, R. Reca M. Majka, Ratajczak M.Z.  SDF-1 stimulation of the X4 HIV-related CXCR4 coreceptor activates the MAPK p42/44 and PI-3K-AKT axes in normal and malignant human hematopoietic cells but does not affect cell proliferation and apoptosisBlood 2000, 96 suppl 1.
113. M. Majka, A. Janowska- Wieczorek, J. Ratajczak, M.A. Kowalska, G. Vilaire, M. Poncz, Ratajczak M.Z.Stromal derived factor-1 (SDF-1) and Thrombopoietin (TPO) regulate distinct aspects of human megakaryopoiesis. Blood 2000, 96 suppl 1.
114.  M. Honczarenko, M. Majka, L. Silberstein, Ratajczak M.Z An evidence that CD4 antigen is not expressed on human bone marrow derived CD34+ stem/progenitor cells.. Blood 2000, 96 suppl 1.
115. J. Ratajczak, M. Majka, C. Mathias, A. Janowska-Wieczorek, Ratajczak M.Z. EPO, KL, IGF-1 and TPO regulate proliferation and apoptosis of normal human CD34+ and early erythroid cells by activating overlapping but distinct signaling pathways. Blood 2000, 96 suppl 1.
116.  A. Janowska-Wieczorek, M. Majka, W. Pear, A.M. Gewirtz, Ratajczak M.Z. Chronic myelogenous leukemia (CML) cells stimulate angiogenesis.  Blood 2000, 96 suppl 1.
117.  A. Janowska-Wieczorek, L.A. Marquez, A. Dobrowsky, A.R.Turner, M. Z. Ratajczak.Inhibition of MMP-2 and MMP-9 activation in Dexter-type LTMC by hydrocortisone is essential for maintaining stromal cell layer integrity and long-term hematopoiesis. Blood 2000, 96 suppl 1.
118. M. Majka, J. Ratajczak, C. Mathias, M.A. Kowalska, Ratajczak M.Z.An evidence that both erythropoietin (EpO) and thrombopoietin  (TpO) activate several signal transduction pathways in normal human CD34+ cells, megekaryoblasts and erythroblasts.    Blood 2000, 96 suppl 1.
119. Ratajczak J, Pertussini E, Majka M, Vaughan D, Ratajczak MZ,  Gewirtz AM. Investigating of the platelet sparing mechanism of the paclitaxel and carboplatin combination chemotherapy. Blood 2000, 96 suppl 1,

 

Annual Meeting of the American Society of Hematology, Orlando 2001, FL
120. Reca R, Majka M, Mastellos D, Ratajczak M.  New unexpected stimulatory effects of complement proteins on human hematopoiesis: Evidence for crosstalk between G-protein-coupled C3a complement receptor (C3aR) and alpha-chemokine SDF-1 receptor (CXCR4). Blood 98 (11): 260 Part 1, 2001.
121. Ratajczak J, Majka M, Janowska-Wieczorek A, Ratajczak M. Evidence that the PI-3K-AKT axis, STAT proteins and MAPK p42/44 are activated in normal human erythroblasts by several „erythropoietic inhibitory cytokines”. Blood 98 (11): 938 Part 1 NOV 16 2001
123. Libura J, Majka M, Janowska-Wieczorek A, Ratajczak M. The CXCR4-SDF-1 axis is involved in metastasis of rhabdomyosarcomas and neuroblastomas to bone marrow and lymph nodes. Blood 98 (11): 1240 Part 1 NOV 16 2001
124. Janowska-Wieczorek A, Majka M, Kijowski J, Ratajczak M. Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment after transplantation. Blood 98 (11): 2706 Part 1 NOV 16 2001
125. Rozmyslowicz T, Majka M, Kijowski J, Ratajczak M. A new role of platelet- and megakaryocyte-derived microparticles (MP) in HIV infection. Blood  98 (11): 3267 Part 1 NOV 16 2001
126. Kijowski J, Majka M, Reca R, Ratajczak M.  The role of newly-identified heterologous crosstalk between G-protein coupled chemokine and complement seven transmembrane span receptors in human thymopoiesis. Blood 98 (11): 3412 Part 1 NOV 16 2001
127. Baj M, Majka M, Kijowski J, Ratajczak M. A new unexpected role for platelet-derived microparticles in regulating proliferation, survival, adhesion and chemotaxis of human normal and malignant hemato/lymphopoietic cells. Blood 98 (11): 3775 Part 2 NOV 16 2001
128. Janowska-Wieczorek A, Majka M, Kijowski J, Ratajczak M. New-found regulators of angiogenesis: Platelet- and tumor-cell-derived microparticles. Blood 98 (11): 3830 Part 2 NOV 16 2001
129. Majka M, Villaire G, Szurpita M, Ratajczak M. Thrombopoietin activates MAPK p42/44, AKT and STAT proteins in normal human CD34(+) cells, megakaryocytes and platelets but gp130 protein-coupled receptor-binding cytokines do not. Blood 98 (11): 4202 Part 2 NOV 16 2001

 

Annual Meeting of the International Society of Hematology, Montreal 2002, Canada

130. Reca R., Majka M., Janowska-Wieczorek A., Lambris J., Ratajczak M.Z. A new unexpected role of the third complement component (C3a)-C3a receptor (C3aR) axis in regulating human hematopoiesis. Exp. Hematol. 30 (6): 92, suppl.1, 2002.
131. Majka M., Kijowski J., Janowska-Wieczorek A., Ratajczak M.Z. Platelet- and tumor-cell-derived microparticles as new-identified regulators of tumor angiogenesis. Exp. Hematol. 30 (6): 155, suppl.1, 2002.
132.  Majka M., Ratajczak J., Janowska-Wieczorek A., Ratajczak M.Z. Thrombin, but not cytokines bonding to pg130 protein-coupled receptors, activates MAPKp42/44, AKT and STAT proteins in normal human CD34+cells, megakaryocytes and platelets. Exp. Hematol. 30 (6): 185, suppl.1, 2002.
133. Libura J., Drukala J., Janowska-Wieczorek A., Barr F., Ratajczak M.Z. CXCR4SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis and adhesion. The role of PAX3-FKHR in expression of CXCR4. Exp. Hematol. 30 (6): 189, suppl.1, 2002.
134. Rozmyslowicz T., Majka M., Kijowski J., Ratajczak M.Z. Platelet-and megakaryocytes-derived particles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV. Exp. Hematol. 30 (6): 92, suppl.1, 2002.

 

Annual Meeting of the American Society of Hematology, Philadelphia 2002, PA
135. Ratajczak J, Majka M, Ratajczak MZ. Membrane Vesicles Derived from Proliferating Murine Embryonic Stem Cells: A New Tool To Expand More Efficient Murine Hematopoietic Stem Cells ex vivo. Blood 2002 100,172a
136. Rozmyslowicz T, Reca R, Murphy SL, Conover DO, Gaulton GN,   Ratajczak MZ.   The Active Fragment of C3 Complement Protein –Anaphylatoxin C3a Inhibits the Infection of T-Lymphocytes by X4 HIV-APossible Role of C3a in Cell Auto-Protection from HIV- Infection. Blood 2002, 100,188a
137. Ratajczak J, Kijowski J, Janowska-Wieczorek A, Ratajczak MZ.   The Unexpected Anti-Apoptotic Effect of TNFs and INFs on Quiescent but Not Epo + KL Stimulated CD 34+ Cells Can Be Explained by the Differential Expression of FLIP: Implications for Anemia of Chronic Disorders. Blood 2002, 100, 234a
138. Majka M,  Pituch Noworolska A,  Drukala J,  Baj- Krzyworzeka M, Malec E, Peiper S, Ratajczak MZ. Evidence That Muscle Stem /Satellite Cells Express CXCR4 and May Compete with Circulating  Hematopoietic Stem Cells for SDF-1 Positive Stem Cell Niches  in Heart and Skeletal Muscles. Blood 2002, 100, 515a
139. Jankowski K,  Libura J, Majka M,  Kucia M, Patocka C, Peiper S,  Janowska Wieczorek A,  Ratajczak MZ,    Crosstalk between G-Protein Coupled CXCR4 and Tyrosine Kinase C-Met Receptor Regulates the Metastatic Behavior of Human Rhabdomyosarcomas. Blood 2002, 100, 728a
140.   Reca R,  Majka M, Ratajczak J,  Janowska Wieczorek A,  Ratajczak MZ. TPO in Combination with IL-3 but Not FLT3, KL or GM-CSF Is Critical for Clinical-Scale Expansion of Megakaryocytic Cells. Blood 2002, 100, 834a.

Annual Meeting of the American Society of Hematology, San Diego, 2003, CA
141. Kucia M, Reca R, Wysoczynski M, Majka M, Janowska-Wieczorek A, Ratajczak J, Ratajczak MZ. Stem cell plasticity revisited: CXCR4-positive cells expressing mRNA for early muscle, liver and neural cells „hide out” in the bone marrow and could be mobilized into peripheral blood. Blood 2003 102 (11): 153B-153B 4322,
142. Janowska-Wieczorek A, Kijowski J, Marquez LA, Ratajczak J, Ratajczak MZ Microvesicles derived from activated platelets: An under-appreciated modulator of the metastatic potential of tumor cells. Blood 102 (11): 73B-73B 3998,
143. Reca R, Ratajczak J, Baran J, Allendorf D, Wysoczynski M, Janowska-Wieczorek A, Ross GD, Ratajczak MZ Transplantation studies in C3-deficient animals reveal a novel role of third complement component (C3) in engraftment/regeneration of bone marrow. Blood 102 (11): 940A-940A 3501
144. Jankowski K, Kucia M, Wysoczynski M, Trzyna E, Ratajczak J, Janowska-Wieczorek A, Ratajczak MZ Both HGF and SDF-1 regulate the metastatic behavior of human rhabdomyosarcoma cells, but only HGF enhances their resistance to radio-chemotherapy. Blood 102 (11): 841A-841A 3124
145. Honczarenko M, Swierkowski M, Le Y, Glodek AM, Ratajczak MZ, Nicholson-Weller A, Silbertsein LE C3a primes B cell responses to SDF-1/CXCL12 by increasing its binding affinity to the CXCR4 chemokine receptor. Blood 102 (11): 823A-823A 3047
146. Janowska-Wieczorek A, Chow L, Shirvaikar N, Reca R, Ratajczak J, Turner AR, Ratajczak MZ Expansion and marrow homing-related potential of umbilical cord blood CFU-Meg: Clinical implications. Blood 102 (11): 694A-694A 2569
147. Kowalska MA, Gewirtz JE, Ratajczak J, Ratajczak MZ, Poncz M Platelet factor 4 has an important in vivo effect on megakaryopoiesis, and thrombopoiesis: Clinical implications. Blood 102 (11): 351A-351A 1272
148. Majka M, Reca R, Kucia M, Ratajczak J, Ratajczak MZ Newly identified crosstalk between the thrombin-PAR-1 and SDF-1-CXCR4 axes regulates trafficking of megakaryocytic cells and pro-platelet formation. Blood 102 (11): 351A-351A 1270
149. Majka M, Zupanska B, Ratajczak MZ Evidence that platelet-derived microvesicles transfer HPA1a antigen to the surface of both endothelial cells and CD34(+) hematopoietic stem/progenitor cells: A new perspective on the pathogenesis of immune thrombocytopenia. Blood 102 (11): 294A-294A 1051
150. Rozmyslowicz T, Murphy SL, Conover DO, Wroblewski K, Ratajczak MZ, Gaulton GN The role of microparticles in HIV-1 infection. Blood 102 (11): 278A-278A 987 Part 1, NOV 16 2003
151. Zhang J, Ratajczak MZ, Ratajczak J A novel strategy to improve ex vivo expansion and maintenance of hematopoietie stem cells using membrane-derived microvesicles from embryonic stem cells. Blood 102 (11): 237A-238A 834
152. Reca R, Kucia M, Wysoczynski M, Ratajczak J, Sirvaikar N, Janowska-Wieczorek A, Ratajczak MZ Because moblized peripheral blood stem/progenitor cells are primed by various inflammatory molecules present in supernatants from leukapheresis products for their chemotactic responses to SDF-1 they engraft faster than bone marrow cells after transplantation. Blood 102 (11): 115A-115A 392
153. Ratajczak J, Reca R, Kucia M, Majka M, Allendorf DJ, Baran J, Wetsel RA, Janowska-Wieczorek A, Ross GD, Ratajczak MZ Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow: Implications for the use of the C3aR antagonist as a new mobilization-facilitating agent. Blood 102 (11): 114A-114A 387
154. Ratajczak MZ, Reca R, Wysoczynski M, Kucia M, Turner RA, Janowska-Wieczorek A, Ratajczak J Priming/increasing responsiveness of hematopoietic stem/progenitor cells (HSPC) to an SDF-1 gradient as a new strategy to improve their engraftment after transplantation. Blood 102 (11): 38A-38A 121

Annual Meeting of the American Society of Hematology, San Diego,2004,CA
155. Ratajczak MZ, Reca R, Wysoczynski M, Kucia M, Turner RA, Janowska-Wieczorek A, Ratajczak J Priming/increasing responsiveness of hematopoietic stem/progenitor cells (HSPC) to an SDF-1 gradient as a new strategy to improve their engraftment after transplantation. Blood 102 (11): 38A-38A 121
156. Reca R, Jankowski K, Przybylski G, Wieczorek AJ, Ratajczak MZ CXCR4 is a PAX family transcription factor regulated gene. Blood 104 (11): 137B-137B 4205
157. Kucia M, Wysoczynski M, Reca R, Majka M, Ratajczak J, Ratajczak MZ More evidence that the phenomenon of „plasticity” of hematopoietic stem cells (HSC) and potential involvement of BM-derived cells in or gan regeneration could be explained by the presence of a heterogenous population of tissue committed stem cells (TCSC) residing/hiding out in bone marrow. Blood 104 (11): 130B-130B 4173
158. Marquez-Curtis LA, Wysoczynski M, Ratajczak MZ, Wieczorek AJ Microvesicles derived from activated platelets enhance the invasive potential of breast cancer cells. Blood 104 (11): 62B-63B 3904
159. Wysoczynski M, Reca R, Kucia M, Ratajczak J, Ratajczak MZ The novel role of the third complement component (C3) in megakaryopoiesis: Implications for pathogenesis of reactive thrombocytosis. Blood 104 (11): 794A-794A 2906
160. Shirvaikar N, Montano J, Turner AR, Ratajczak MZ, Janowska-Wieczorek A Upregulation of MT1-MMP expression by hyaluronic acid enhances homing-related responses of hematopoietic CD34(+) cells to an SDF-1 gradient. Blood 104 (11): 790A-790A 2889
161. Kucia M, Ping ZY, Ratajczak J, Ildstad ST, Shields C, Ratajczak MZ Evidence that CXCR4(+) neural tissue-committed stem cells (TCSC) reside/hide out in the bone marrow and are mobilized into the peripheral blood during stroke. Blood 104 (11): 737A-737A 2698
162. Son BR, Zhao DL, Marquez-Curtis LA, Shirvaikar N, Ratajczak MZ, Janowska-Wieczorek A SDF-1-CXCR4 and HGF-c-met axes regulate mobilization/recruitment to injured tissue of human mesenchymal stem cells. Blood 104 (11): 642A-642A 2331
163. Rezzoug F, Huang YM, Tanner MK, Wysoczynski M, Shannie CL, Ratajczak MZ, Fugier-Vivier IJ, Ildstad ST TNF alpha mediated facilitating cell enhancement of hematopoietic stem cell function in vivo and in vitro involves Bcl-3. Blood 104 (11): 597A-598A 2174
164. Kucia M, Dawn B, Guo YR, Hunt G, Wysoczynski M, Majka M, Zuba E, Rezzoug F, Ildstad ST, Bolli R, Ratajczak MZ CXCR4(+) CD45(-) tissue-committed stem cells (TCSC) for myocardium reside in the bone marrow, are mobilized into the peripheral blood during myocardial infarction, and „home” to infarcted myocardium in CXCR4-SDF-1 and HGF/SF-c-Met dependent manner. Blood 104 (11): 586A-586A 2131
165. Huang YM, Kucia M, Rezzoug F, Ratajczak MZ, Tanner M, Schanie C, Xu H, Fugier I, Ildstad ST Promotion of chimerism and tolerance by Flt3 ligand-mobilized facilitating cells is associated with upregulation of CXCR4 and SDF-1. Blood 104 (11): 363A-363A 1286
166. Wysoczynski M, Jankowski K, Miekus K, Kucia M, Janowska-Wieczorek A, Ratajczak J, Ratajczak MZ Leukemia Inhibitory Factor: A newly identified chemoattractant and regulator of metastasis of rhabdomyosarcomas and neuroblastomas to bone marrow. Blood 104 (11): 361A-361A 1278
167. Kucia M, Reca R, Wysoczynski M, Gozdzik J, Ratajczak J, Janowska-Wieczorek AJ, Ratajczak MZ A potential new application of mobilization/leukapheresis for enrichment of peripheral blood in circulating non-hematopoietic CXCR4(+)CD45(-) tissue-committed stem cells (TCSC) for organ/tissue regeneration. Blood 104 (11): 46A-47A 151.

Annual Meeting of the American Society of Hematology, Atlanta, 2005, GA
168. Kucia M, Paczkowska E, Majka M, Machaliński B, Ratajczak MZ, Evidence that Functional Neural Tissue-Committed stem Cells (NTCSC) reside in the Human Bone Marrow and are mobilized into Peripheral Blood in a Patients after stroke. Blood 106 (11): 118a, 392
169. Wysoczyński M, Hayek F, Ratajczak J, Janowska-Wieczorek A, Ratajczak MZ, Membrane Derived Microvesicles – underappreciated components of the Tumor Microenvironment that modulate Tumor Growth, Vascularization and Metastasis. Blood 106 (11): 142a, 473
170. Kucia M, Ołdak K, Ratajczak MZ, Ratajczak J, Pojda Z, Percoll gradient separation of Cord Blood Mononuclear cells reveals the presence of a novel population of CXCR4+ Oct-4+small Embryonic-Like Stem Cells. Blood 106 (11): 311a, 1069
171. Reca R, Kucia M, Baran J, Ratajczak J, Ratajczak MZ, Defective engraftment of HSPC from C3aR-/- mice reveals an underappreciated role of C3a-C3aR axis in Stem Cell homing to Bone Marrow. Blood 106 (11): 366a, 1259
172. Iidstad ST, Rezzoug F, Huang Y, Wysoczyński M, Schanie CL, Ratajczak MZ, Fugier-Vivier IJ, CD8+/TCR- graft facilitating cells enhance HSC engraftment and survival via TNF-α mediated prevention of apoptosis. Blood 106 (11): 392a, 1352
173. Marquez-Curtis LA, Shirvaikar N, Larratt LM, Turner AR, Ratajczak MZ, Janowska-Wieczorek A, Stem Cell mobilization and egress of AML blasts from the Bone Marrow are both regulated by MT-MMP-Mediated activation of MMP-2. Blood 106 (11): 396a, 1368
174. Majka M, Jarocha D, Wysoczyński M, Sag D, Zuba-Surma E, Kijowski J, Goździk J, Ratajczak MZ, Unexpected evidence that Dimethylsulphoxide (DMSO) upregulates expression of CXCR4 on Hematopoietic Stem/Progenitor Cells (HSPC), increases their responsiveness to an SDF-1 gradient and enhances homing to Bone Marrow. Blood 106(11): 559a, 1973
175. Reca R, Wysoczyński M, Hansen R, Kucia M, Janowska-Wieczorek A, Ratajczak J, Ratajczak MZ, Immunodeficient mice are poor mobilizers – novel evidence that demonstrates a pivotal role of complement in triggering mobilization of HSPC. Blood 106 (11): 560a, 1976
176. Wysoczyński M, Reca R, Kucia M, Ratajczak J, Ratajczak MZ, Novel evidence that Statin-Mediated perturbation of Lipid Raft Formation ameliorates bleeding – related Thrombocytosis. Blood 106 (11): 611a, 2164
177. Miękus K, Wysoczyński M, Reca R, Goździk J, Salvatore BJ, Janowska-Wieczorek A, Ratajczak MZ, LIF-LIF-R and SDF-1-CXCR4 Axes regulate overlapping and complementary steps of Metastasis of Rhabdomyosarcoma – implication for developing better antimetastatic therapies. Blood 106 (11): 646a, 2296
178. Majka M, Jurczyszyn A, Zebzda A, Czogała W, Leśko E, Rudzki Z, Goździk J, Wolska-Smolen T, Skotnicki AB, Ratajczak MZ, C-met Receptor as a potential target for the treatment of patients with Multiple Myeloma. Blood 106 (11): 948a, 3395
179. Kucia M, Reca R, Ratajczak J, Ratajczak MZ, A population of small CXCR4+ SSEA-1+ Oct-4+ Embryonic-Like Stem Cells identified in adult bone marrow. Blood 106 (11): 1009a, 3623
180. Shirvaikar N, Montano J, Turner AR, Ratajczak MZ, Janowska-Wieczorek A, Upregulation of MT1-MMP by Molecules present in Leukaphereis products primers CD34+ Cel Homing. Blood 106 (11): 402b, 5273

Annual Meeting of the American Society of Hematology, Orlando, FL, 2006
181.Fanning LR, Finney MR, Pompili VJ, Greco NJ, Lazarus HM, Kozik M, Meyerson, Nair R, Maciejewski J, Tary-Lehmann M, Ratajczak MZ, Laughlin MJ, Umbilical Cord Blood Derived CD133+ Hematopoietic Stem Cells Are Defective Antigen Presenting Cells (APC), Lack Expressoin of Co-Stimulatory Receptors, and generate TH2 T-lymphocyte Responses In Vitro. Blood 2006, 108 (11): 489a, 1723
182. Hegerfeldt Y, Fanning LR, Fu P, Lazarus HM, Cooper B, Tse W, Meyerson H, Gerson SL, Jarscak J, Fox R, Creger R, Maciejewski J, Tary-lehmann, Ratajczak M, Stevens C, Rubinsetin P, Hoffman MA, Laughlin MJ, Umbilical cord Blood (UCB) Graft T-Cells Correlate with Myeloid Recovery in Adults with Hematologic Malignancies Treated with Reduced Intensity Conditioning (RIC) and Single Unit Infusion. Blood 2006, 108 (11): 893a
183. Marquez-Curtis LA, Montano J, Quinn D, Larratt LM, Turner AR, Ratajczak M, Janowska-Wieczorek A, In Vitro Chemotactic Index and Response to CXCR4 Antagonist AMD3100 Correlate with CD34+ Cell Yield from Leukapheresis Products: Implications for Poor Mobilizers. Blood 2006, 108 (11): 218a
184. Wagner S, Cramer D, Hansen R, Reca R, Ratajczak M, Li B, Beta Glucan Enhances Hematopoietic Stem Cell Mobilization. Blood 2006, 108 (11): 394a
185. Kucia M, Zuba-Surma E, Reca R, Ratajczak J, Ratajczak M, An Evidence That Murine Marrow-Derived CXCR4+ SSEA-1+ Oct-4+ Very Small Embryonic-Like (VSEL) Stem Cells Are Pluripotent and Express Several Primordial Germ Cell (PGC) Markers – Hypothesis for Developmental Deposition of PGC in Various Organs. Blood 2006, 108 (11): 478a
186. Ratajczak J, Kucia M, Zuba-Surma E, Reca R, Ratajczak M, The CD45-LIN- Adult Marrow-Derived CXCR4+ SSEA-1+ Oct-4+ Very Small Embryonic-Like (VSEL) Stem Cells Form In Vitro Spheres Which May Differentiate into CD45+ Hematopoietic Cells. Blood 2006, 108 (11): 86a
187. Reca R, Wysoczynski M, Ratajczak J, Ratajczak M, Impaired Engraftment of Hematopoietic Stem/Progenitor Cells (HSPC) in Immunodeficient Mice Supports an Important Role of Complement System for Optimal Homing. Blood 2006, 108 (11): 105a
188. Ratajczak J, Reca R, Machalinski B, Maciejewski, Laughlin M, Ratajczak M, The Unexpected Role of C3a-C3aR Axis in Maturation of Erythroid Cells-Implications for Pathogenesis of Hypoxia-Related Polycythemias. Blood 2006, 108 (11): 196a
189. Wysoczynski M, Miekus, Marcinkowska A, Janowska-Wieczorek A, Ratajczak M, An In Vitro and In Vivo Evidence That Downregulation of Leukemia Inhibitory Factor (LIF) Receptor (LIF-R) Decreases the Metastatic Potential of Human Rhabdomyosarcoma (RMS) Cells. Blood 2006, 108 (11): 724a
190. Jarocha D, Lesko E, Ratajczak M, Majka M, Comparison of Different Strategies of MSC Isolation Revels Advantage To Expand MSC Directly from Purified CD105+ and CD271+ Cells. Blood 2006, 108 (11): 725a
191. Shirvaikar N, Turner R, Ratajczak M, Janowska-Wieczorek A, Fibrinogen Enhances Homing-Related Responses of CD34+ by Incorporating Membrane Type1-Matrix Metalloproteinase into Membrane Lipid Rafts. Blood 2006, 108 (11): 910a
192. Kucia M, Halasa M, Wysoczynski M, Baskiewicz-Masiuk M, Zuba-Surma E, Machalinksi B, Ratajczak M, A Novel Population of Oct-4+ SSEA-1+ CXCR4+ CD34+ CD133+ Lin- CD45- Very Small Embryonic-Like (VSEL) Stem Cells Identified in Human Cord Blood. Blood 2006, 108 (11): 912a
193. Shirvaikar N, Jalili A, Ratajczak M, Janowska-Wieczorek A, A Novel Role for Thrombin in Hematopoietic Stem/Progenitor Cell Homing. Blood 2006, 108 (11): 963a
194. Reca R, Wysoczynski M, Kucia M, Janowska-Wieczorek A, Ratajczak J, Ratajczak M, Mobilization Studies in Immunodeficient Mice Support a Role of Complement in Modulating the Trafficking of Hematopoietic Stem Cells (HSC) – A Pivotal Role of C3 Cleavage Fragments in Retention and C5 Fragments in Mobilization/Egress of HSc. Blood 2006, 108 (11): 963a

Annual Meeting of the American Society of Hematology, Atlanta, GA, 2007
195. Wysoczynski M, Kucia M, Zuba-Surma E, Wu W, Ratajczak M, Ratajczak J. An In Vivo Evidence that the CD45- Adult Marrow-Derived CXCR4+ SSEA-1+ OCT-4+ Very Small Embryonic-Like (VSEL) Stem Cells May Differentiate into CD45+ Long Term Repopulating Hematopoietic Stem Cells. Blood 2007, 110 (11): 505.
196. Wysoczynski M, Reca R, Wu W, Kucia M, Botto M, Ratajczak J, Ratajczak M. The Studies in Various Murine Strains with Defects in Activation of Complement Cascade (CC) Reveal Both Pivotal and Pleiotropic Role of CC in Mobilization of Hematopoietic Stem/Progenitor Cells. Blood 2007, 110 (11): 774.
197. Kucia M, Wysoczynski M, Wu W, Ratajczak M. Novel Direct Evidence That Adult Bone Marrow-Derived Very Small Embryonic Like (VSEL) Stem Cells are Mobilized into Peripheral Blood – Leukopheresis as a Potential Tool to Isolate Pluripotent Stem Cells for Therapeutic Purposes. Blood 2007, 110 (11): 1205.
198. Jalili A, Shirvaikar N, Ratajczak M, Janowska-Wieczorek A. C1q Complement Cascade Protein as a Novel Modulator of the SDF-1-CXCR4 Axis and Hematopoietic Stem/Progenitor Cell Trafficking. Blood 2007, 110 (11): 1212.
199. Wang Z, Junghun J, Kucia M, Junhui S, Shiozawa Y, Ratajczak M, Krebsbach P, Taichman R. Prospective in vivo Identificatio of Osteogenic Stem/Progenitor Cells from Bone Marrow-Derived Lin~/Sca-1+/CD45-Cells. Blood 2007, 110 (11): 1409.
200. Jalili A, Shirvaikar N, Ilnitsky S, Turner A, Ratajczak M, Janowska-Wieczorek. G-CSF Induces Expression of Both Hepatocyte Growth Factor (HGF) and Its Receptor (c-Met) in Human Hematopoietic Stem/Progenitor Cells and Mature Myeloid Cells – Novel Evidence that during Mobilization the HGF-c-Met Axis Counterbalances G-CSF-Induced Attenuation of the SDF-1-CXCR4 Axis. Blood 110 (11): 2203.
201. Ratajczak J, Wysoczynski M, Bogdan M, Janowska-Wieczorek A, Ratajczak M. Complement Cascade (CC) Cleavage Fragments – C3a and C5a Anaphylatoxins – As New Unexpected Hypoxia-Related Stimulators of Erythropoiesis. Blood 2007, 110 (11): 2220.
202. Zuba-Surma E, Kucia M, Yiru G, Dawn B, Bolli R, Ratajczak M. An In Vivo Evidence that Murine Very Small Embyronic Like (VSEL) Stem Cells are Mobilized into Peripheral Blood after Acute Myocardiac Regeneration. Blood 2007, 110 (11): 3694.
203. Kucia M, Zuba E, Wu W, Boguslaw M, Wojtek W, Ratajczak M. Pluripotent SSEA-1+ OCT-4+ CXCR4+ Sca-1+ lin- CD45- Very Small Embryonic Like (VSEL) Stem Cells Reside in Multiple Murine Organs – Are VSEL Epiblast-Derived Functional Pluripotent Precursors for Tissue-Committed Stem Cells or Merely Quesiscent Remnants from Embryonic Development? Blood 2007, 110 (11): 3698.
204. Kucia M, Paczkowska E, Koziarska D, Halasa M, Safranow K, Karbicka A, Nowik M, Nowacki P, Ratajczak M, Machalinski B. Clinical Evidence that Very Small Embryonic Like (VSEL) Stem Cells are Mobilized into Peripheral Blood in Patients after Stroke. Blood 2007, 110 (11) 3705.

50 th Annual Meeting of the American Society of Hematology, San Francisco, December 2008:
205. Wu W, Lee H, Wysoczynski M, Kucia M, Ratajczak J, Ratajczak M. Novel Observation That Mice Lacking the Fifth Comlement Cascade Protein Component (C5) Are Very Poor Stem Cell Mobilizers Explained by Defective Egress of Granulocytes: A Novel Role for Bone Marrow Granulocytes to Act as ”Ice Breaker” Cells in Facilitating Egress of Hematopoietic Stem/Progenitor Cells. Blood 2008, 112 (11) 67.
206. Shin DM, Zuba-Surma E, Ratajczak M, Kucia M. The Unique Pattern of Somatic Impront in Oct-4+ Very Small Embryonic Like (VSEL) Stem Cells Isolated from Adult Tissues Further Supports Both Their Epiblast/Germ Line Origin and Explains Quiescent Status: Potential Modification of Somatic Imprint as a Key to Longevity. Blood 2008, 112 (11) 385.
207. Wysoczynski M, Ratajczak M. Novel Pleiotropic Effects of Thrombia in Regulation of The Metastatic Potential of Human Rhabdomyosarcoma (RMS) Cells. Blood 2008, 112 (11) 2270.
208. Zuba-Surma E, Kucia M, Klich I, Greco N, Laughlin M, Paul P, Ratajczak M, Ratajczak J. Optimization of Isolation and Further Molecular and Functional Characterization of SSEA-4+/Oct-4+/CD133+CXCR4+/Lin-/CD45- Very Small Embryonic-Like (VSEL) Stem Cells Isolated from Umbilical Cord Blood. Blood 2008 112 (11) 2316.
209. Zuba-Surma E, Kucia M, Liu R, Ratajczak M, Ratajczak J. CD45-/ALDHlow/SSEA-4+/Oct-4+/CD133+/CSCR4+/Lin- Very Small Embryonic-Like (VSEL) Stem Cells Isolated from Umbilical Cord Blood as Potential Long Term Repopulating Hematopoietic Stem Cells. Blood 2008 112 (11) 2444.
210. Wojakowski W, Tendera M, Kucia M, Zuba-Surma E, Paczkowska E, Ciosek J, Halasa M, Krol M, Kazmierski M, Ochala A, Ratajczak M, Ratajczak J. Clinical Evidence That Oct-4+ ssea-4+ Very Small Embryonic Like Stem Cells (VSEL) Are Mobilized Into Peripheral Blood in Patients with Acute Myocardial Infarction (AMI): A Novel Prognostic Indicator. Blood 2008 112 (11) 2894.

51st Annual Meeting of the American Society of Hematology, New Orlens, Louisiana, December 2009:
211. Lee H, Wysoczynski M, Wu W, Liu R, Kucia MJ, Janowska-Wieczorek A, Ratajczak J, Ratajczak MZ. Novel Mechanistic Insight Into Mobilization of Hematopoietic Stem/Progenitor Cells (HSPCs): Complement Cascade and Membrane Attack Complex Activated in Bone Marrow Sinusoids During Mobilization Release From Erythrocytes Sphingosine-1 Phosphate – An Underappreciated Chemoattractant Executing Egress of HSPCs. Blood 2009, 114, (22) 31.
212. Zuba-Surma E, Klich I, Wysoczynski M, Greco NJ, Laughlin MJ, Ratajczak MZ, Ratajczak J. In Vitro and In Vivo Evidence That Umbilical Cord Blood (UCB)-Derived CD45-/SSEA-4+/OCT-4+/CD133+/CXCR4+/Lin- Very Small Embryonic/Epiblast Like Stem Cells (VSELs) Do Not Contain Clonogenic Hematopoietic Progenitors but Are Highly Enriched in More Primitive Stem Cells – Novel View On Hierarchy of UCB Stem Cell Compartment. Blood 2009, 114, (22) 35.
213. Wysoczynski M, Liu R, Ratajczak MZ. Novel Pleiotropic Effects of Thrombin in Regulation of Metastatic Potential of Human Rhabdomyosarcoma (RMS) Cells – Identification of Negative PAR1 and PAR3 Receptor Crosstalk. Blood 2009, 114, (22) 336.
214. Wysoczynski M, Lee H, Liu R, Wu W, Ratajczak J, Ratajczak MZ. Mobilization Studies in Complement-Deficient Mice Reveal That AMD3100 Mobilization Depends On Complement Cascade Activation and Suggest Involvement of “Membrane Attack Complex – MAC” in Egress of Hematopoietic Stem/Progenitor Cells. Blood 2009, 114, (22) 367.
215. Lee H, Wu W, Wysoczynski M, Kucia MJ, Laughlin MJ, Ratajczak J, Ratajczak MZ. Granulocyte-Derived Cationic Peptides (GDCPs) Present in Leucophoresis Products Enhance Homing of Hematopoietic Stem Cells (HSCs) to SDF-1 Gradient; Potential Implications for Accelerated Recovery of Hematopoiesis After Transplantation of Mobilized Peripheral Blood Stem Cells (PBSC). Blood 2009, 114, (22) 371.
216. Medicetty S, Ratajczak MZ, Kucia MJ, Zuba-Surma E, Klich I, Marasco WA, Rodgerson DO. Evidence That Human Very Small Embryonic-Like Stem Cells (VSELs) Are Mobilized by G-CSF Into Peripheral Blood: A Novel Strategy to Obtain Human Pluripotent Stem Cells for Regenerative Medicine. Blood 2009, 114, (22) 1474.
217. Ratajczak, MZ, Shin, DM, Zuba-Surma, E, Liu, R, Yoshimoto M, Yoder, MC, Kucia MJ. Very Small Embryonic/Epiblast-Like Stem Cells (VSELs) – Novel Supporting Evidence for An Existence of Developmentally Distinct Mobile Pool of Oct-4+ Pluripotent Stem Cells in Embryonic and Adult Tissues: Emerging Concept for a Potential 4th Migratory Germ Layer? Blood 2009, 114, (22) 1480.
218. Klich I, Tarnowski M, Shin DM, Ratajczak J, Kucia MJ, Ratajczak MZ. Quiescent Status of Very Small Embryonic Like Stem Cells (VSELs) Points to Pivotal Role of Autocrine Role of Insulin-Like Growth Factor-2 (Igf2) – Ras-Activating Guanine Nucleotide Exchange Factor (Rasgrf1) Axis in Regulating Proliferation of Embryonic Stem Cells. Blood 2009, 114, (22) 1484.
219. Shin DM, Zuba-Surma E, Liu R, Ratajczak MZ, Kucia MJ. Genetic and Epigenetic Studies Reveal That Murine Oct-4+ Very Small Embryonic/Epiblast-Like Stem Cells (VSELs) Present in Adult Tissues Share Several Similarities/Markers with Epiblast-Derived Migratory Primordial Germ Cells (PGCs). Blood 2009, 114, (22) 2521.

52nd Annual Meeting of the American Society of Hematology, Orlando, FL, 2010
220. Kim CH, Wu W, Abdel-Latif A, Wysoczynski M, Kucia M, Ratajczak J, Ratajczak MZ. Evidence That a Bioactive Lipid, Ceramide-1 Phosphate (C1P), Is Upregulated In Bone Marrow Microenvironment After Myeloablative Therapy and Is a Potential Novel Homing Factor for Hematopoietic Stem Cells Kim. Blood 2010, 116 (21), 179.
221. Kim CH, Wu W, Liu R, Kucia M, Laughlin MJ, Ratajczak J, Ratajczak MZ. A Novel Paradigm In Stem Cell Trafficking: The Ratio of Peripheral Blood Sphingosine-1 Phosphate (S1P) to Bone Marrow Ceramide-1 Phosphate (C1P) Regulates Mobilization and Homing of Hematopoietic Stem Cells. Blood 2010, 116, (21), 246.
222. Kim CH, Wu W, Liu R, Kucia M, Ratajczak J, Ratajczak MZ. An Unexpected Role for the Complement C5b-C9 Membrane Attack Complex (MAC) In Trafficking of Hematopoietic Stem/Progenitor Cells – a Novel Unexpected Link Between Innate Immunity and Hematopoiesis. Blood 2010, 116, (21), 246.
223. Greco NJ, Lesnewski M, Wendling A, Kalipraveena I, Ratajczak J, Ratajczak, Laughlin MJ. Negative influence of IL8 and RANTES Ctyokines on cord blood CD133+ cell SDF-1-CXCR4 Function. Blood 2010, 116, (21), 505.
224. Ratajczak J, Wu W, Liu R, Shin DM, Kucia M, Bartke A, Ratajczak MZ. Unexpected Evidence That Chronic IGF-1 Deficiency In Laron Dwarf Mice Maintains High Levels of Hematopoietic Stem Cells (HSCs) In BM – Are HSCs Gradually Depleted From BM with Age In An IGF-1–dependent Manner? Implications for the Novel Effect of Caloric Restriction on the Hematopoietic Stem Cell Compartment and Longevity. Blood 2010, 116, (21), 659.
225. Tarnowski M, Liu R, Tarnowska J, Ratajczak J, Mitchell R, Ratajczak MZ, Kucia M. Novel Evidence That the Small Chemokine Macrophage Migration Inhibitory Factor (MIF) Is Highly Secreted by Human Rhabdomyosarcomas, Activates Both SDF-1–binding Receptors, CXCR4 and
CXCR7, and Unexpectedly Inhibits Recruitment of Stromal Cells to the Growing Tumor. Blood 2010, 116, (21), 1575.

53rd Annual Meeting of the American Society of Hematology, San Diego, CA, 2011
226. Wen Y, Elliot M, Huang Y, Corbin D, Fukui Y, Ratajczak M. Critical Role for DOCK2 in CD8+/ TCR- Graft Facilitating Cells Enhancing Engraftment of Hematopoietic Stem Cells. Blood 2011, 118 (21), 68.
227. Wysoczynski M, Ratajczak J, Rokosh G, Bolli R, Ratajczak M. A Novel Observation That Heme Oxygenase-1 (HO-1) Deficient Mice Are Easy Mobilizers and That HO-1 Plays An Important Role in Maintaining Expression of SDF-1 in Bone Marrow (BM) Stroma and Promotes Retention of Hematopoietic Stem/Progenitor Cells (HSPCs) in the Bone Marrow Microenvironment. Blood 2011, 118 (21), 147.
228. Schneider G, Bryndza E, Kim C, Ratajczak J, Kucia M, Ratajczak M. Novel View on Unwanted Side Effects of Radio-Chemotherapy on Bone Marrow (BM) Microenvironment – Radio-Chemotherapy Upregulates BM-Level of Bioactive Lipids, Sphingosine-1- Phosphate (S1P) and Ceramide-1-Phosphate (C1P), That Chemoattract Metastasizing Cancer Cells. Blood 2011, 118 (21), 329.
229. Ratajczak J, Liu R, Natarajan N, Maciejewski J, Sharma V, Ratajczak M. A Novel View of Paroxysmal Nocturnal Hemoglobinuria (PNH) Pathogenesis: Do Pathologic PNH Hematopoietic Stem/Progenitor Cells (HSPCs) Displace Normal HSPCs From Their Niches in Bone Marrow Because They Are More Motile Due to Defective Adhesion and Enhanced Migratory Properties? Blood 2011, 118 (21), 332.
230. Kucia M, Liu R, Mierzejewska K, Wu W, Ratajczak J, Shin D, Ratajczak M. Single Cell Level Genome-Wide Gene Expression Analysis of Bone Marrow-Derived Oct-4+ very Small Embryonic-Like Stem Cells (VSELs) Revealed That a Polycomb Group Protein Ezh2 Regulates VSELs Pluripotency by Maintaining Bivalent Domains At Promoters of Important Homeodomain-Containing Developmental Transcription Factors. Blood 2011, 118 (21), 1014.
231. Kim C, Liu R, Kucia M, Ratajczak M. New Evidence That the Bioactive Lipid Ceramide-1-Phosphate (C1P) Is a Potent Chemoattractant for Mesenchymal Stromal Cells (MSC), Endothelial Progenitor Cells (EPCs) and Very Small Embryonic-Like Stem Cells (VSELs), Demonstrating Its Potential Involvement in Tissue/Organ Repair and Angiogenesis. . Blood 2011, 118 (21), 1028.
232. Kim C, Wu W, Greco N, Kucia M, Ratajczak J, Laughlin M, Ratajczak M. A Novel Perspective on Stem Cell Homing – Emerging Interplay Between Bioactive Lipids As Potent Chemoattractants and Cationic Peptides As Underappreciated Modulators of Responsiveness to SDF-1 Gradients. Blood 2011, 118 (21), 1276.
233. Abdel-Latif A, Karapetyan A, Kim C, Ratajczak M. Differential Responsiveness of HSPCs Harvested From Bone Marrow (BM), Mobilized Peripheral Blood (mPB) and Umbilical Cord Blood (UCB) to the BM Homing Factors Stromal-Derived Factor-1 (SDF-1), Sphingosine-1 Phosphate (S1P) and Ceramide-1 Phosphate (C1P) Is Related to the Desensitization of mPB and UCB HSPCs by S1P and C1P Present in mPB and UCB Plasma. Blood 2011, 118 (21), 1276.
234. Farmar J, Wendling A, Lynch K, Tomsig J, Ratajczak M, Lu H, Salhtra A, Yang S, Huang X, Masri H, Laughlin M. Cord Blood Plasma Enhances Migration of Hematopoietic Stem and Progenitor Cells (HSPC). Blood 2011, 118 (21), 1277.
235. Ratajczak J, Liu R, Kucia M, Bartke A, Ratajczak M. Long-Term In Vivo Studies in Mice Unexpectedly Reveal That Prolonged Growth Hormone (GH) and Insulin/Insulin-Like Growth Factor-1 (IGF-1) Signaling Have a Negative Effect on Normal Bone Marrow Hematopoiesis – Implications for GH-Based “rejuvenation” Therapies. Blood 2011, 118 (21), 1463.

54th Annual Meeting of the American Society of Hematology, Atlanta, GA 2012
236. Mierzejewska K, Rodriguez C, Sharma V, Kucia M, Maciejewski J, Ratajczak J, Ratajczak M. Novel Evidence That PNH Affected Cells Residing in Bone Marrow (BM) Due to Impaired Incorporation of CXCR4 and VLA-4 Into Membrane Lipid Rafts Show Defective SDF-1- and VCAM-1-Mediated Retention in BM What Leads to Their Increased Motility and Impaired Interaction with the BM Stem Cell Niches. Blood, Nov 2012; 120: 1256.
237. Schneider G, ChiHwa K, Abdel-Latif A, Janowska-Wieczorek A, Ratajczak J, Ratajczak M. A Novel Perspective on Hematopoietic Stem/Progenitor Cell Homing – an Expanding Family of Bone Marrow Homing Factors That Can Support SDF-1-Mediated Homing or Even Replace SDF-1. Blood, Nov 2012; 120: 1247.
238. Janowska-Wieczorek A, Marquez-Curtis A, Leontyev D, Branch D, Ratajczak J, Ratajczak M. Studies in C4b-Deficient Mice Provide Further Evidence That Complement Cascade Orchestrates the Mobilization of Hematopoietic Stem/Progenitor Cells. Blood, Nov 2012; 120: 2316.
239. Schneider G, Serwin K, Bryndza E, Kucia M, Ratajczak J, Ratajczak M. Studies with Diluted Plasma Reveal the Presence of a Remarkably Potent Factor That Enhances the Motility of Cancer Cells and Is Quentched by Fibrinogen – a Novel View of Cancer Metastasis. Blood, Nov 2012; 120: 3431.
240. Wysoczynski M, Ratajczak J, Rokosh G, Bolli R, Ratajczak M. Further Evidence That HO-1 Regulates SDF-1 Expression in the Bone Marrow Microenvironment and That HO-1-Deficient Mice Show a Defect in the SDF-1–CXCR4 Retention Axis of Hematopoietic Stem/Progenitor Cells in Bone Marrow and Thus Are Easy Mobilizers – Studies in HO-1 Mutant Mice, Irradiation Chimeras, and the Effect of in Vivo Pharmacological Inhibition of HO-1. Blood, Nov 2012; 120: 344.
241. Ratajczak M, Mierzejewska K, Ratajczak J, Kucia M. Novel Evidence That a Quiescent Murine Population of Bone Marrow (BM)-Residing, Developmentally Early, Very Small Sca-1+Lin–CD45– Cells Is Highly Responsive to Prolonged Bleeding by in Vivo Proliferation and Differentiation Into CD45+ Hematopoietic Stem/Progenitor Cells (HSPCs). Blood, Nov 2012; 120: 1249.
242. Schneider G, Kim C, Ratajczak J, Ratajczak M. A Novel Perspective On Hematopoietic Stem/Progenitor Cell Migration and homing—evidence That Cationic Antimicrobial Peptides (C3a, LL-37, and β2-defensin) Prime (enhance) the Responsiveness of These Cells to a Low SDF-1 Gradient by Promoting Secretion of ATP, Indicating the Involvement of an Autocrine Purinergic Loop in Their Migration. Blood, Nov 2012; 120: 2989.
243. Mierzejewska K, Kucia M, Ratajczak J, Ratajczak M. Novel Evidence That Hematopoietic Stem/Progenitor Cells (HSPCs) Are Mobilized During Hemolysis in an Erythrocyte Lysis-Derived, Sphingosine-1-Phosphate (S1P)-Dependent manner—the Crucial Involvement of Complement Cascade (CC) Activation and Attenuation of CXCR4 Retention Signaling. Blood, Nov 2012; 120: 3189.
244. Grymula K, Tarnowski M, Suszynska M, Piotrowska K, Borkowska S, Mierzejewska K, Kucia M, Ratajczak M. A Novel View of Bone Marrow As a “stem Cell sensor” of Tissue/Organ Damage -Evidence That in Vivo Exposure to the Neurotoxin Kainic Acid (KA) Induces Proliferation and Neural Specification of Developmentally Early Stem Cells Directly in Bone Marrow before They Are Mobilized into Peripheral Blood. Blood, Nov 2012; 120: 1192.
245. Abdel Latif A, Karapetyan A, Klyachkin Y, Sunkara M, Smyth S, Ratajczak M, Morris A. Novel Role for Bioactive Lipids in Mobilization of Bone Marrow Stem Cells during Myocardial Ischemia: Sphingosine-1 Phosphate (S1P) As Potential Therapeutic Target. Blood, Nov 2012; 120: 1911.
246. Tarnowski M, Piotrowska K, Grymula K, Suszynska M, Poniewierska A, Ratajczak M. Prolonged Strenuous Exercise Expands the Population of Developmentally Early Stem Cells in Bone Marrow (BM) and Mobilizes Them Into Peripheral Blood – Novel Evidence That Strongly Supports a Positive Effect of Physical Activity On Extension of Life Span At the Level of Stem Cells. Blood, Nov 2012; 120: 584.
247. Mierzejewska K, Kucia M, Ratajczak J, Ratajczak M. Novel Evidence for the Presence of Potent, Paracrine, Pro-Angiopoietic Effects of Purified Human Umbilical Cord Blood-Derived CD133+ Cells – Implications for Adult Stem Cell Therapies in Regenerative Medicine. Blood, Nov 2012; 120: 4740.
248. Kucia M, Mierzejewska K, Shin D, Ma Y, Ratajczak M. Most Primitive Murine Bone Marrow Hematopoietic Stem Cells Express Several Primordial Germline Cells (PGCs) Markers, Including SALL4 – a Proposed Developmental Link Between Hematopoietic and Primordial Germ Cell Lineages. Blood, Nov 2012; 120: 4745.

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